PITA_186 megaCluster: 3 Residual: 0.18 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_186	3	0.18	15	0	0.929541	0

Members

Displaying 1 - 25 of 25

14011 ets variant gene 6 (TEL oncogene) Details for - - ets variant gene 6 (TEL oncogene) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14011 Tuberculist Genomic Region	14086 fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) Details for - - fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14086 Tuberculist Genomic Region
170829 translocating chain-associating membrane protein 2 Details for - - translocating chain-associating membrane protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170829 Tuberculist Genomic Region	19108 protein kinase, X-linked Details for RP23-91C19.5 - protein kinase, X-linked GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19108 Tuberculist Genomic Region
19663 RNA binding protein gene with multiple splicing Details for - - RNA binding protein gene with multiple splicing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19663 Tuberculist Genomic Region	20656 superoxide dismutase 2, mitochondrial Details for - - superoxide dismutase 2, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20656 Tuberculist Genomic Region
210106 PAP associated domain containing 7 Details for - - PAP associated domain containing 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 210106 Tuberculist Genomic Region	21887 transducin-like enhancer of split 3, homolog of Drosophila E(spl) Details for - - transducin-like enhancer of split 3, homolog of Drosophila E(spl) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21887 Tuberculist Genomic Region
227449 zinc finger, CCHC domain containing 2 Details for - - zinc finger, CCHC domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 227449 Tuberculist Genomic Region	228994 YTH domain family 1 Details for RP23-359C15.7 - YTH domain family 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228994 Tuberculist Genomic Region
100034251 WAP four-disulfide core domain 17 Details for RP23-430I21.1 - WAP four-disulfide core domain 17 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100034251 Tuberculist Genomic Region	100504453 predicted gene, 20236 Details for - - predicted gene, 20236 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504453 Tuberculist Genomic Region
11787 amyloid beta (A4) precursor protein-binding, family B, member 2 Details for - - amyloid beta (A4) precursor protein-binding, family B, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11787 Tuberculist Genomic Region	14284 fos-like antigen 2 Details for - - fos-like antigen 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14284 Tuberculist Genomic Region
15957 interferon-induced protein with tetratricopeptide repeats 1 Details for - - interferon-induced protein with tetratricopeptide repeats 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15957 Tuberculist Genomic Region	16634 killer cell lectin-like receptor, subfamily A, member 3 Details for - - killer cell lectin-like receptor, subfamily A, member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16634 Tuberculist Genomic Region
170676 paternally expressed 10 Details for - - paternally expressed 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170676 Tuberculist Genomic Region	18578 phosphodiesterase 4B, cAMP specific Details for RP23-57D24.1 - phosphodiesterase 4B, cAMP specific GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18578 Tuberculist Genomic Region
20310 chemokine (C-X-C motif) ligand 2 Details for - - chemokine (C-X-C motif) ligand 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20310 Tuberculist Genomic Region	231130 TNFAIP3 interacting protein 2 Details for - - TNFAIP3 interacting protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231130 Tuberculist Genomic Region
269181 mannoside acetylglucosaminyltransferase 4, isoenzyme A Details for - - mannoside acetylglucosaminyltransferase 4, isoenzyme A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269181 Tuberculist Genomic Region	320975 RIKEN cDNA D330050G23 gene Details for - - RIKEN cDNA D330050G23 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320975 Tuberculist Genomic Region
55935 formin binding protein 4 Details for RP23-322I11.2 - formin binding protein 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 55935 Tuberculist Genomic Region	56382 RAB9, member RAS oncogene family Details for RP23-408K4.3 - RAB9, member RAS oncogene family GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56382 Tuberculist Genomic Region
73158 La ribonucleoprotein domain family, member 1 Details for RP23-293I3.7 - La ribonucleoprotein domain family, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73158 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_CEBPB_Q6_M01896	0.26087	0.00000671

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0048	TTTNTTTTTYTT	NA	1600	CSGCCCCTCCCC	SP1_MA0079.2, Klf4_MA0039.2, V$CKROX_Q2_M01175, V$SP4_Q5_M01273, V$UF1H3BETA_Q6_M01068, V$ZFP281_01_M01597, V$MAZ_Q6_M00649, V$SP1_Q6_01_M00931, V$SP1_02_M01303, V$SP1_03_M02281, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$MAZR_01_M00491, V$SP1_Q2_01_M00933, V$GC_01_M00255, V$MAZ_Q6_01_M02023, V$ZNF219_01_M01122, V$KLF7_03_M02773, V$ZBP89_Q4_M01816, V$GKLF_02_M01588, V$KLF15_Q2_M01714, V$ZFP281_04_M02831, V$KROX_Q6_M00982, V$NFE4_Q5_M02105, V$ZFP410_04_M02936, V$ZFP740_03_M02834, V$FPM315_01_M01587, V$BCL6B_04_M02844, V$MZF1_02_M00084, V$SP1SP3_Q4_M01219, V$CACD_01_M01113, V$SP2_01_M01783, V$EGR1_Q6_M01873, V$SMAD4_04_M02898, V$FKLF_Q5_M01837, V$ETF_Q6_M00695, V$CACBINDINGPROTEIN_Q6_M00720, V$EGR1_06_M02744, Klf7.1, Zfp281.2, Zfp410.1, Zfp740.1, Bcl6b.2, Smad3.1, Egr1.1, Sp4.1, Ascl2.2, Glis2.1, Gcm1.2, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.11	CCGCGT	NA	1.26	GCGGNCCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.6	CGTGTC	NA	NA	0.91	TTTTCNCN	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-871	0.857143	0.0000099

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-3073-3p	0.454545	0.00000847

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