PITA_203 megaCluster: 9 Residual: 0.20 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_203	9	0.20	15	0	0.927267	0

Members

Displaying 1 - 34 of 34

320528 vacuolar protein sorting 13C (yeast) Details for - - vacuolar protein sorting 13C (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320528 Tuberculist Genomic Region	66881 prenylcysteine oxidase 1 Details for - - prenylcysteine oxidase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66881 Tuberculist Genomic Region
101185 protection of telomeres 1A Details for - - protection of telomeres 1A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 101185 Tuberculist Genomic Region	11781 adaptor-related protein complex AP-4, mu 1 Details for - - adaptor-related protein complex AP-4, mu 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11781 Tuberculist Genomic Region
16498 potassium voltage-gated channel, shaker-related subfamily, beta member 2 Details for RP23-421E12.12-005 - potassium voltage-gated channel, shaker-related subfamily, beta member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16498 Tuberculist Genomic Region	17826 family with sequence similarity 89, member B Details for - - family with sequence similarity 89, member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17826 Tuberculist Genomic Region
20148 dehydrogenase/reductase (SDR family) member 3 Details for RP23-133N19.1 - dehydrogenase/reductase (SDR family) member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20148 Tuberculist Genomic Region	209815 TBC1 domain family, member 25 Details for RP23-27I6.9 - TBC1 domain family, member 25 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209815 Tuberculist Genomic Region
215201 TRM2 tRNA methyltransferase 2B Details for RP23-162B19.2 - TRM2 tRNA methyltransferase 2B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 215201 Tuberculist Genomic Region	216190 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 Details for - - adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216190 Tuberculist Genomic Region
22619 sialic acid acetylesterase Details for - - sialic acid acetylesterase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22619 Tuberculist Genomic Region	226744 consortin, connexin sorting protein Details for - - consortin, connexin sorting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226744 Tuberculist Genomic Region
228607 mitochondrial antiviral signaling protein Details for RP23-387C21.3 - mitochondrial antiviral signaling protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228607 Tuberculist Genomic Region	229521 synaptotagmin XI Details for - - synaptotagmin XI GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229521 Tuberculist Genomic Region
232984 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 Details for - - UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 232984 Tuberculist Genomic Region	330812 ring finger protein 150 Details for - - ring finger protein 150 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 330812 Tuberculist Genomic Region
333433 glycerol-3-phosphate dehydrogenase 1-like Details for - - glycerol-3-phosphate dehydrogenase 1-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 333433 Tuberculist Genomic Region	380912 zinc finger protein 395 Details for - - zinc finger protein 395 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 380912 Tuberculist Genomic Region
56541 hyaluronic acid binding protein 4 Details for - - hyaluronic acid binding protein 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56541 Tuberculist Genomic Region	66659 acid phosphatase 6, lysophosphatidic Details for - - acid phosphatase 6, lysophosphatidic GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66659 Tuberculist Genomic Region
66928 transmembrane protein 261 Details for RP24-200F10.1 - transmembrane protein 261 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66928 Tuberculist Genomic Region	68731 ribosome binding factor A Details for - - ribosome binding factor A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68731 Tuberculist Genomic Region
69024 sorting nexin 15 Details for - - sorting nexin 15 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69024 Tuberculist Genomic Region	69091 vacuolar protein sorting 26 homolog B (yeast) Details for - - vacuolar protein sorting 26 homolog B (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69091 Tuberculist Genomic Region
69769 tumor necrosis factor, alpha-induced protein 8-like 2 Details for - - tumor necrosis factor, alpha-induced protein 8-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69769 Tuberculist Genomic Region	70719 histocompatibility (minor) HA-1 Details for - - histocompatibility (minor) HA-1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70719 Tuberculist Genomic Region
70750 3-ketodihydrosphingosine reductase Details for - - 3-ketodihydrosphingosine reductase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70750 Tuberculist Genomic Region	71904 progestin and adipoQ receptor family member VII Details for - - progestin and adipoQ receptor family member VII GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71904 Tuberculist Genomic Region
71972 dynamin binding protein Details for - - dynamin binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71972 Tuberculist Genomic Region	72017 cytochrome b5 reductase 1 Details for - - cytochrome b5 reductase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72017 Tuberculist Genomic Region
74478 sorting nexin 29 Details for - - sorting nexin 29 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74478 Tuberculist Genomic Region	76467 methionine sulfoxide reductase B2 Details for RP23-34E4.2 - methionine sulfoxide reductase B2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76467 Tuberculist Genomic Region
76594 DnaJ (Hsp40) homolog, subfamily C, member 18 Details for - - DnaJ (Hsp40) homolog, subfamily C, member 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76594 Tuberculist Genomic Region	77219 prostaglandin reductase 2 Details for - - prostaglandin reductase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77219 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
NA

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000000000036	AARAAAAAAAM	NA	3.6	CCMCCCCCNCCC	Klf4_MA0039.2, SP1_MA0079.2, V$ZFP281_04_M02831, V$SP1_02_M01303, V$SP4_Q5_M01273, V$SP1_Q6_01_M00931, V$SP1_Q2_01_M00933, V$KLF7_03_M02773, V$SP1_Q4_01_M00932, V$MAZ_Q6_01_M02023, V$CACD_01_M01113, V$GKLF_02_M01588, V$ZFP281_01_M01597, V$KROX_Q6_M00982, V$GC_01_M00255, V$ZFP740_03_M02834, V$SP1_Q6_M00196, V$ZNF219_01_M01122, V$SP1SP3_Q4_M01219, V$UF1H3BETA_Q6_M01068, V$SP1_03_M02281, V$EKLF_Q5_M01874, V$ASCL2_04_M02841, V$CKROX_Q2_M01175, V$EGR1_Q6_M01873, V$BCL6B_04_M02844, V$FKLF_Q5_M01837, V$EGR1_06_M02744, V$MAZR_01_M00491, V$MAZ_Q6_M00649, V$MOVOB_01_M01104, V$NFE4_Q5_M02105, V$SMAD4_04_M02898, V$ZFP410_04_M02936, V$EGR2_Q6_M02092, V$CACCCBINDINGFACTOR_Q6_M00721, V$ZBP89_Q4_M01816, V$CACBINDINGPROTEIN_Q6_M00720, V$WT1_Q6_01_M02036, V$FPM315_01_M01587, Zfp281.2, Klf7.1, Zfp740.1, Bcl6b.2, Ascl2.2, Egr1.1, Zfp410.1, Smad3.1, Sp4.1, Sox13.2, Zif268.1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, Zfp740_C2H2_DBD_monomeric_10_1, ZNF740_C2H2_full_monomeric_10_1, SP8_C2H2_DBD_monomeric_12_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.08	CGCGTA	NA	1.17	TGGCGCGA	V$E2F_Q2_M00803, V$E2F1_Q3_01_M00938, V$E2F_03_M00516, V$E2F_Q6_01_M00920, V$E2F_Q4_01_M00919, V$E2F_Q4_02_M00939, V$SMAD4_04_M02898, V$E2F_Q3_01_M00918, V$E2F3_Q6_M02089, V$ZF5_01_M00716, Smad3.1

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.62	CCGGCA	NA	NA	0.74	CASGAGNG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-1982.1	0.387097	0.0000479

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