TargetScan_106 megaCluster: 11 Residual: 0.23 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_106	11	0.23	12	0	0.841017	0

Members

Displaying 1 - 38 of 38

100038519 predicted gene 9900 Details for - - predicted gene 9900 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100038519 Tuberculist Genomic Region	101513 MOB kinase activator 2 Details for - - MOB kinase activator 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 101513 Tuberculist Genomic Region
109785 phosphoglucomutase 3 Details for - - phosphoglucomutase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109785 Tuberculist Genomic Region	11792 apurinic/apyrimidinic endonuclease 1 Details for - - apurinic/apyrimidinic endonuclease 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11792 Tuberculist Genomic Region
12367 caspase 3 Details for - - caspase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12367 Tuberculist Genomic Region	12785 cellular nucleic acid binding protein Details for - - cellular nucleic acid binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12785 Tuberculist Genomic Region
16019 immunoglobulin heavy constant mu Details for - - immunoglobulin heavy constant mu GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16019 Tuberculist Genomic Region	17122 Max dimerization protein 4 Details for - - Max dimerization protein 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17122 Tuberculist Genomic Region
17846 COMM domain containing 1 Details for RP23-242C19.3 - COMM domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17846 Tuberculist Genomic Region	19769 Ras-like without CAAX 1 Details for - - Ras-like without CAAX 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19769 Tuberculist Genomic Region
20088 ribosomal protein S24 Details for - - ribosomal protein S24 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20088 Tuberculist Genomic Region	216987 UTP6, small subunit (SSU) processome component, homolog (yeast) Details for RP23-253E9.3 - UTP6, small subunit (SSU) processome component, homolog (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216987 Tuberculist Genomic Region
22027 heat shock protein 90, beta (Grp94), member 1 Details for - - heat shock protein 90, beta (Grp94), member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22027 Tuberculist Genomic Region	22083 Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) Details for - - Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22083 Tuberculist Genomic Region
52502 calcium regulated heat stable protein 1 Details for - - calcium regulated heat stable protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52502 Tuberculist Genomic Region	52653 NudC domain containing 2 Details for RP23-382C18.4 - NudC domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52653 Tuberculist Genomic Region
52713 coiled-coil domain containing 59 Details for - - coiled-coil domain containing 59 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52713 Tuberculist Genomic Region	56095 FtsJ homolog 3 (E. coli) Details for RP23-418O11.2 - FtsJ homolog 3 (E. coli) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56095 Tuberculist Genomic Region
56464 cathepsin F Details for - - cathepsin F GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56464 Tuberculist Genomic Region	66469 family with sequence similarity 213, member B Details for RP23-15L19.6 - family with sequence similarity 213, member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66469 Tuberculist Genomic Region
68015 TNF receptor-associated protein 1 Details for - - TNF receptor-associated protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68015 Tuberculist Genomic Region	68347 RIKEN cDNA 0610011F06 gene Details for - - RIKEN cDNA 0610011F06 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68347 Tuberculist Genomic Region
68475 Sjogren's syndrome nuclear autoantigen 1 Details for RP23-132N23.16-003 - Sjogren's syndrome nuclear autoantigen 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68475 Tuberculist Genomic Region	69151 leucine zipper and CTNNBIP1 domain containing Details for RP23-153G17.1 - leucine zipper and CTNNBIP1 domain containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69151 Tuberculist Genomic Region
71340 RIO kinase 1 (yeast) Details for - - RIO kinase 1 (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71340 Tuberculist Genomic Region	99889 ADP-ribosylation factor interacting protein 1 Details for - - ADP-ribosylation factor interacting protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99889 Tuberculist Genomic Region
19139 neural precursor cell expressed, developmentally down-regulated gene 8 Details for - - neural precursor cell expressed, developmentally down-regulated gene 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18002 Tuberculist Genomic Region	67487 phosphoribosyl pyrophosphate synthetase 1 Details for RP23-137E3.3 - phosphoribosyl pyrophosphate synthetase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19139 Tuberculist Genomic Region
67510 DEAH (Asp-Glu-Ala-His) box polypeptide 40 Details for RP23-366M19.4 - DEAH (Asp-Glu-Ala-His) box polypeptide 40 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67487 Tuberculist Genomic Region	72284 trans-golgi network vesicle protein 23B Details for RP23-428I5.3 - trans-golgi network vesicle protein 23B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67510 Tuberculist Genomic Region
18634 oral cancer overexpressed 1 Details for - - oral cancer overexpressed 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72284 Tuberculist Genomic Region	27398 peroxisomal biogenesis factor 7 Details for - - peroxisomal biogenesis factor 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18634 Tuberculist Genomic Region
54638 mitochondrial ribosomal protein L2 Details for RP23-76I16.2 - mitochondrial ribosomal protein L2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27398 Tuberculist Genomic Region	56451 coiled-coil domain containing 22 Details for - - coiled-coil domain containing 22 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54638 Tuberculist Genomic Region
107197 succinate-CoA ligase, GDP-forming, alpha subunit Details for - - succinate-CoA ligase, GDP-forming, alpha subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56451 Tuberculist Genomic Region	69125 expressed sequence AI462493 Details for - - expressed sequence AI462493 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107197 Tuberculist Genomic Region
104112 CCR4-NOT transcription complex, subunit 8 Details for RP23-293I3.1 - CCR4-NOT transcription complex, subunit 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69125 Tuberculist Genomic Region	Details for RP23-392I3.9 - ATP citrate lyase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104112 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
Etv6.1	0.388889	0.00000369

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000000000000018	AAAAAAAAAAAA	NA	0.0011	GCCCCGCCCMC	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$GC_01_M00255, V$SP1_Q6_01_M00931, V$KLF7_03_M02773, V$SP1_Q2_01_M00933, V$SP4_Q5_M01273, V$GKLF_02_M01588, V$SP1_03_M02281, V$SP2_01_M01783, V$MAZR_01_M00491, V$SMAD4_04_M02898, V$ZFP281_01_M01597, V$E2F3_Q6_M02089, V$SP1_01_M00008, V$SP4_03_M02810, V$UF1H3BETA_Q6_M01068, V$SP1_02_M01303, V$CKROX_Q2_M01175, V$KROX_Q6_M00982, V$CACD_01_M01113, V$ZFP740_03_M02834, V$MAZ_Q6_01_M02023, V$ZNF219_01_M01122, V$ZFP281_04_M02831, V$EGR1_06_M02744, V$EGR1_Q6_M01873, V$SP4_04_M02914, V$MAZ_Q6_M00649, V$EGR_Q6_M00807, V$SP1SP3_Q4_M01219, V$ZBP89_Q4_M01816, V$EKLF_Q5_M01874, V$E2F_Q2_M00803, V$EGR1_02_M01972, V$NGFIC_01_M00244, V$BCL6B_04_M02844, Klf7.1, Smad3.1, Sp4.1, Zfp740.1, Egr1.1, Zfp281.2, Zif268.1, Sp4.2, Bcl6b.2, Zfp410.1, Ascl2.2, SP4_C2H2_full_monomeric_17_1, SP1_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, KLF16_C2H2_DBD_monomeric_11_1, KLF13_C2H2_full_monomeric_18_1, Klf12_C2H2_DBD_monomeric_15_1, ZNF740_C2H2_full_monomeric_10_1, Zfp740_C2H2_DBD_monomeric_10_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, EGR2_C2H2_full_monomeric_15_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.46	ATCGCG	NA	1.36	CCGNCGCG	Max.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.69	AGNAGGAC	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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