TargetScan_194 megaCluster: 8 Residual: 0.22

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_194	8	0.22	15	0	0.906637	0

Members

Displaying 1 - 46 of 46

TFBS DB TF

TFs	percTargets	pValue
V_RNF96_01_M01199	0.826087	0.00000234

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000013	AAANAARCAAAA	NA	0.0021	GCCCCGCCCCY	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$SP4_Q5_M01273, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$GC_01_M00255, V$SP1_Q6_01_M00931, V$SP1_Q2_01_M00933, V$KLF7_03_M02773, V$SP1_02_M01303, V$GKLF_02_M01588, V$ZFP281_01_M01597, V$UF1H3BETA_Q6_M01068, V$SP1_03_M02281, V$CKROX_Q2_M01175, V$SP4_03_M02810, V$MAZR_01_M00491, V$ZFP281_04_M02831, V$SP1_01_M00008, V$MAZ_Q6_M00649, V$SP2_01_M01783, V$SMAD4_04_M02898, V$BCL6B_04_M02844, V$CACD_01_M01113, V$E2F3_Q6_M02089, V$KLF15_Q2_M01714, V$EGR1_06_M02744, V$KROX_Q6_M00982, V$ZFP410_04_M02936, V$EGR1_Q6_M01873, V$ZBP89_Q4_M01816, V$ZNF219_01_M01122, V$MAZ_Q6_01_M02023, V$ZFP740_03_M02834, V$SP1SP3_Q4_M01219, V$ETF_Q6_M00695, V$EKLF_Q5_M01874, V$WT1_Q6_01_M02036, V$SP4_04_M02914, Klf7.1, Sp4.1, Zfp281.2, Smad3.1, Bcl6b.2, Egr1.1, Zfp410.1, Zfp740.1, Sp4.2, Ascl2.2, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, KLF13_C2H2_full_monomeric_18_1, KLF14_C2H2_DBD_monomeric_14_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, Klf12_C2H2_DBD_monomeric_15_1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.23	CGGCGT	NA	1.25	CGGCAGTC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.46	CGCGGT	NA	NA	0.54	ACGCNGTC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-3097-3p	0.375	0.0000376

21991 triosephosphate isomerase 1 Details for - - triosephosphate isomerase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21991 Tuberculist Genomic Region	22390 WEE 1 homolog 1 (S. pombe) Details for - - WEE 1 homolog 1 (S. pombe) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22390 Tuberculist Genomic Region
109145 GINS complex subunit 4 (Sld5 homolog) Details for - - GINS complex subunit 4 (Sld5 homolog) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109145 Tuberculist Genomic Region	117591 solute carrier family 2 (facilitated glucose transporter), member 9 Details for - - solute carrier family 2 (facilitated glucose transporter), member 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 117591 Tuberculist Genomic Region
11920 ataxia telangiectasia mutated homolog (human) Details for - - ataxia telangiectasia mutated homolog (human) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11920 Tuberculist Genomic Region	13830 stomatin Details for RP23-186B18.3 - stomatin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13830 Tuberculist Genomic Region
13852 syntaxin 2 Details for - - syntaxin 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13852 Tuberculist Genomic Region	14894 gene trap locus 3 Details for - - gene trap locus 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14894 Tuberculist Genomic Region
16909 LIM domain only 2 Details for RP23-261L3.1 - LIM domain only 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16909 Tuberculist Genomic Region	17218 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) Details for - - minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17218 Tuberculist Genomic Region
17979 nuclear receptor coactivator 3 Details for RP23-120P1.1 - nuclear receptor coactivator 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17979 Tuberculist Genomic Region	18010 neuraminidase 1 Details for - - neuraminidase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18010 Tuberculist Genomic Region
19655 RNA binding motif protein, X chromosome Details for RP23-372E6.2 - RNA binding motif protein, X chromosome GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19655 Tuberculist Genomic Region	207425 WD repeat domain 11 Details for - - WD repeat domain 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 207425 Tuberculist Genomic Region
217666 L-2-hydroxyglutarate dehydrogenase Details for - - L-2-hydroxyglutarate dehydrogenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217666 Tuberculist Genomic Region	224014 FYVE, RhoGEF and PH domain containing 4 Details for - - FYVE, RhoGEF and PH domain containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 224014 Tuberculist Genomic Region
224617 TBC1 domain family, member 24 Details for - - TBC1 domain family, member 24 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 224617 Tuberculist Genomic Region	229615 protein inhibitor of activated STAT 3 Details for - - protein inhibitor of activated STAT 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229615 Tuberculist Genomic Region
232807 protein phosphatase 1, regulatory (inhibitor) subunit 12C Details for - - protein phosphatase 1, regulatory (inhibitor) subunit 12C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 232807 Tuberculist Genomic Region	26412 mitogen-activated protein kinase kinase kinase kinase 2 Details for - - mitogen-activated protein kinase kinase kinase kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26412 Tuberculist Genomic Region
56187 Rab geranylgeranyl transferase, a subunit Details for - - Rab geranylgeranyl transferase, a subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56187 Tuberculist Genomic Region	56218 POZ (BTB) and AT hook containing zinc finger 1 Details for RP23-191E3.5 - POZ (BTB) and AT hook containing zinc finger 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56218 Tuberculist Genomic Region
56462 mitochondrial carrier homolog 1 (C. elegans) Details for - - mitochondrial carrier homolog 1 (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56462 Tuberculist Genomic Region	60534 Fanconi anemia, complementation group G Details for RP23-124L1.6 - Fanconi anemia, complementation group G GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 60534 Tuberculist Genomic Region
66522 pyroglutamyl-peptidase I Details for - - pyroglutamyl-peptidase I GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66522 Tuberculist Genomic Region	67278 PAXIP1 associated glutamate rich protein 1A Details for - - PAXIP1 associated glutamate rich protein 1A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67278 Tuberculist Genomic Region
67698 family with sequence similarity 174, member A Details for - - family with sequence similarity 174, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67698 Tuberculist Genomic Region	68041 Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) Details for RP23-130J1.1 - Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68041 Tuberculist Genomic Region
68240 replication protein A3 Details for - - replication protein A3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68240 Tuberculist Genomic Region	68845 PIH1 domain containing 1 Details for - - PIH1 domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68845 Tuberculist Genomic Region
69683 ER membrane protein complex subunit 10 Details for - - ER membrane protein complex subunit 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69683 Tuberculist Genomic Region	71778 kelch-like 5 Details for - - kelch-like 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71778 Tuberculist Genomic Region
72181 NOL1/NOP2/Sun domain family, member 4 Details for RP23-383D12.4 - NOL1/NOP2/Sun domain family, member 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72181 Tuberculist Genomic Region	72549 receptor accessory protein 4 Details for - - receptor accessory protein 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72549 Tuberculist Genomic Region
72568 lin-9 homolog (C. elegans) Details for - - lin-9 homolog (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72568 Tuberculist Genomic Region	76773 WDYHV motif containing 1 Details for - - WDYHV motif containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76773 Tuberculist Genomic Region
76795 TBC1 domain family, member 9B Details for RP23-319B15.5 - TBC1 domain family, member 9B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76795 Tuberculist Genomic Region	13433 DNA methyltransferase (cytosine-5) 1 Details for - - DNA methyltransferase (cytosine-5) 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13433 Tuberculist Genomic Region
16443 intersectin 1 (SH3 domain protein 1A) Details for - - intersectin 1 (SH3 domain protein 1A) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16443 Tuberculist Genomic Region	216527 cerebral cavernous malformation 2 Details for RP23-169J19.3 - cerebral cavernous malformation 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216527 Tuberculist Genomic Region
241303 family with sequence similarity 78, member A Details for RP23-55I14.8 - family with sequence similarity 78, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241303 Tuberculist Genomic Region	56249 ARP8 actin-related protein 8 Details for - - ARP8 actin-related protein 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56249 Tuberculist Genomic Region
70650 zinc finger, CCHC domain containing 8 Details for - - zinc finger, CCHC domain containing 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70650 Tuberculist Genomic Region	26406 mitogen-activated protein kinase kinase kinase 3 Details for RP23-81G14.5 - mitogen-activated protein kinase kinase kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26406 Tuberculist Genomic Region
14247 Friend leukemia integration 1 Details for - - Friend leukemia integration 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14247 Tuberculist Genomic Region	12566 cyclin-dependent kinase 2 Details for - - cyclin-dependent kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12566 Tuberculist Genomic Region

TargetScan_194 megaCluster: 8 Residual: 0.22

Summary

Members

Details for - - triosephosphate isomerase 1

Details for - - WEE 1 homolog 1 (S. pombe)

Details for - - GINS complex subunit 4 (Sld5 homolog)

Details for - - solute carrier family 2 (facilitated glucose transporter), member 9

Details for - - ataxia telangiectasia mutated homolog (human)

Details for RP23-186B18.3 - stomatin

Details for - - syntaxin 2

Details for - - gene trap locus 3

Details for RP23-261L3.1 - LIM domain only 2

Details for - - minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)

Details for RP23-120P1.1 - nuclear receptor coactivator 3

Details for - - neuraminidase 1

Details for RP23-372E6.2 - RNA binding motif protein, X chromosome

Details for - - WD repeat domain 11

Details for - - L-2-hydroxyglutarate dehydrogenase

Details for - - FYVE, RhoGEF and PH domain containing 4

Details for - - TBC1 domain family, member 24

Details for - - protein inhibitor of activated STAT 3

Details for - - protein phosphatase 1, regulatory (inhibitor) subunit 12C

Details for - - mitogen-activated protein kinase kinase kinase kinase 2

Details for - - Rab geranylgeranyl transferase, a subunit

Details for RP23-191E3.5 - POZ (BTB) and AT hook containing zinc finger 1

Details for - - mitochondrial carrier homolog 1 (C. elegans)

Details for RP23-124L1.6 - Fanconi anemia, complementation group G

Details for - - pyroglutamyl-peptidase I

Details for - - PAXIP1 associated glutamate rich protein 1A

Details for - - family with sequence similarity 174, member A

Details for RP23-130J1.1 - Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

Details for - - replication protein A3

Details for - - PIH1 domain containing 1

Details for - - ER membrane protein complex subunit 10

Details for - - kelch-like 5

Details for RP23-383D12.4 - NOL1/NOP2/Sun domain family, member 4

Details for - - receptor accessory protein 4

Details for - - lin-9 homolog (C. elegans)

Details for - - WDYHV motif containing 1

Details for RP23-319B15.5 - TBC1 domain family, member 9B

Details for - - DNA methyltransferase (cytosine-5) 1

Details for - - intersectin 1 (SH3 domain protein 1A)

Details for RP23-169J19.3 - cerebral cavernous malformation 2

Details for RP23-55I14.8 - family with sequence similarity 78, member A

Details for - - ARP8 actin-related protein 8

Details for - - zinc finger, CCHC domain containing 8

Details for RP23-81G14.5 - mitogen-activated protein kinase kinase kinase 3

Details for - - Friend leukemia integration 1

Details for - - cyclin-dependent kinase 2

GO Terms

3p UTR PITA