TargetScan_208 megaCluster: 2 Residual: 0.17

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_208 2 0.17 15 0 0.942604 0

Members

Displaying 1 - 33 of 33
107607 nucleotide-binding oligomerization domain containing 1

Details for - - nucleotide-binding oligomerization domain containing 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 107607

Tuberculist Genomic Region

20715 serine (or cysteine) peptidase inhibitor, clade A, member 3G

Details for - - serine (or cysteine) peptidase inhibitor, clade A, member 3G

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20715

Tuberculist Genomic Region

22793 zyxin

Details for - - zyxin

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22793

Tuberculist Genomic Region

100504219 predicted gene, 20117

Details for - - predicted gene, 20117

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100504219

Tuberculist Genomic Region

11492 a disintegrin and metallopeptidase domain 19 (meltrin beta)

Details for RP23-29H5.4 - a disintegrin and metallopeptidase domain 19 (meltrin beta)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11492

Tuberculist Genomic Region

11540 adenosine A2a receptor

Details for - - adenosine A2a receptor

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11540

Tuberculist Genomic Region

12822 collagen, type XVIII, alpha 1

Details for - - collagen, type XVIII, alpha 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12822

Tuberculist Genomic Region

13614 endothelin 1

Details for - - endothelin 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13614

Tuberculist Genomic Region

16169 interleukin 15 receptor, alpha chain

Details for RP23-114B13.4 - interleukin 15 receptor, alpha chain

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16169

Tuberculist Genomic Region

170755 serum/glucocorticoid regulated kinase 3

Details for - - serum/glucocorticoid regulated kinase 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 170755

Tuberculist Genomic Region

18126 nitric oxide synthase 2, inducible

Details for RP23-341J22.2 - nitric oxide synthase 2, inducible

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18126

Tuberculist Genomic Region

18950 purine-nucleoside phosphorylase

Details for - - purine-nucleoside phosphorylase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18950

Tuberculist Genomic Region

20351 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

Details for - - sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20351

Tuberculist Genomic Region

22271 uridine phosphorylase 1

Details for RP23-104F14.1 - uridine phosphorylase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22271

Tuberculist Genomic Region

227659 solute carrier family 2 (facilitated glucose transporter), member 6

Details for RP23-449M10.2 - solute carrier family 2 (facilitated glucose transporter), member 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 227659

Tuberculist Genomic Region

240047 matrix metallopeptidase 25

Details for - - matrix metallopeptidase 25

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 240047

Tuberculist Genomic Region

243197 major facilitator superfamily domain containing 7A

Details for - - major facilitator superfamily domain containing 7A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 243197

Tuberculist Genomic Region

246779 interleukin 27

Details for - - interleukin 27

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 246779

Tuberculist Genomic Region

269356 solute carrier family 4, sodium bicarbonate transporter-like, member 11

Details for - - solute carrier family 4, sodium bicarbonate transporter-like, member 11

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 269356

Tuberculist Genomic Region

27416 ATP-binding cassette, sub-family C (CFTR/MRP), member 5

Details for - - ATP-binding cassette, sub-family C (CFTR/MRP), member 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 27416

Tuberculist Genomic Region

329795 transmembrane protein 67

Details for RP23-203A12.5 - transmembrane protein 67

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 329795

Tuberculist Genomic Region

330723 HtrA serine peptidase 4

Details for - - HtrA serine peptidase 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 330723

Tuberculist Genomic Region

381560 X Kell blood group precursor related family member 8 homolog

Details for RP23-442A20.2 - X Kell blood group precursor related family member 8 homolog

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 381560

Tuberculist Genomic Region

434204 WAS protein homolog associated with actin, golgi membranes and microtubules

Details for - - WAS protein homolog associated with actin, golgi membranes and microtubules

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 434204

Tuberculist Genomic Region

620913 predicted gene 12185

Details for RP23-14F5.7 - predicted gene 12185

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 620913

Tuberculist Genomic Region

652925 transmembrane protein 243, mitochondrial

Details for - - transmembrane protein 243, mitochondrial

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 652925

Tuberculist Genomic Region

671535 poly (ADP-ribose) polymerase family, member 10

Details for - - poly (ADP-ribose) polymerase family, member 10

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 671535

Tuberculist Genomic Region

69104 membrane-associated ring finger (C3HC4) 5

Details for - - membrane-associated ring finger (C3HC4) 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69104

Tuberculist Genomic Region

69217 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

Details for - - pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69217

Tuberculist Genomic Region

71704 Rho guanine nucleotide exchange factor (GEF) 3

Details for - - Rho guanine nucleotide exchange factor (GEF) 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71704

Tuberculist Genomic Region

74096 hydrogen voltage-gated channel 1

Details for - - hydrogen voltage-gated channel 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74096

Tuberculist Genomic Region

74123 forkhead box P4

Details for - - forkhead box P4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74123

Tuberculist Genomic Region

74481 basic leucine zipper transcription factor, ATF-like 2

Details for - - basic leucine zipper transcription factor, ATF-like 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74481

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
IRF9_IRF_full_trimeric_15_1 0.34375 0.000000324

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.0000014 TNTTTTSTTYT NA 8.5 CTCCTNCTCTCT NA

Upstream Weeder Motif

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.7 CCGCTA NA NA 0.8 CCGCGCCG mmu-mir-1893 7mer_m8

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-5124 0.461538 0.0000149

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