TargetScan_209 megaCluster: 3 Residual: 0.19

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_209 3 0.19 13 0 0.875302 0

Members

Displaying 1 - 25 of 25
11787 amyloid beta (A4) precursor protein-binding, family B, member 2

Details for - - amyloid beta (A4) precursor protein-binding, family B, member 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11787

Tuberculist Genomic Region

12289 calcium channel, voltage-dependent, L type, alpha 1D subunit

Details for - - calcium channel, voltage-dependent, L type, alpha 1D subunit

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12289

Tuberculist Genomic Region

12870 ceruloplasmin

Details for - - ceruloplasmin

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12870

Tuberculist Genomic Region

170768 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Details for RP23-428M4.3 - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 170768

Tuberculist Genomic Region

17130 SMAD family member 6

Details for - - SMAD family member 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17130

Tuberculist Genomic Region

17131 SMAD family member 7

Details for - - SMAD family member 7

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17131

Tuberculist Genomic Region

17329 chemokine (C-X-C motif) ligand 9

Details for - - chemokine (C-X-C motif) ligand 9

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17329

Tuberculist Genomic Region

17342 microphthalmia-associated transcription factor

Details for - - microphthalmia-associated transcription factor

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17342

Tuberculist Genomic Region

17936 Ngfi-A binding protein 1

Details for - - Ngfi-A binding protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17936

Tuberculist Genomic Region

17937 Ngfi-A binding protein 2

Details for - - Ngfi-A binding protein 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17937

Tuberculist Genomic Region

17940 NLR family, apoptosis inhibitory protein 1

Details for - - NLR family, apoptosis inhibitory protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17940

Tuberculist Genomic Region

17948 NLR family, apoptosis inhibitory protein 2

Details for RP23-333E24.2 - NLR family, apoptosis inhibitory protein 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17948

Tuberculist Genomic Region

18227 nuclear receptor subfamily 4, group A, member 2

Details for RP23-271B15.1 - nuclear receptor subfamily 4, group A, member 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18227

Tuberculist Genomic Region

19108 protein kinase, X-linked

Details for RP23-91C19.5 - protein kinase, X-linked

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19108

Tuberculist Genomic Region

226562 proline-rich coiled-coil 2C

Details for - - proline-rich coiled-coil 2C

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 226562

Tuberculist Genomic Region

227449 zinc finger, CCHC domain containing 2

Details for - - zinc finger, CCHC domain containing 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 227449

Tuberculist Genomic Region

246728 2'-5' oligoadenylate synthetase 2

Details for - - 2'-5' oligoadenylate synthetase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 246728

Tuberculist Genomic Region

269966 nucleoporin 98

Details for - - nucleoporin 98

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 269966

Tuberculist Genomic Region

545384 cDNA sequence BC094916

Details for - - cDNA sequence BC094916

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 545384

Tuberculist Genomic Region

546325 predicted gene 5936

Details for RP23-459K15.9 - predicted gene 5936

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 546325

Tuberculist Genomic Region

54711 pleiomorphic adenoma gene-like 2

Details for RP23-192G18.4 - pleiomorphic adenoma gene-like 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 54711

Tuberculist Genomic Region

67434 ankyrin repeat domain 33B

Details for - - ankyrin repeat domain 33B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67434

Tuberculist Genomic Region

70675 valosin containing protein (p97)/p47 complex interacting protein 1

Details for - - valosin containing protein (p97)/p47 complex interacting protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70675

Tuberculist Genomic Region

19271 protein tyrosine phosphatase, receptor type, J

Details for RP24-113P16.2 - protein tyrosine phosphatase, receptor type, J

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19271

Tuberculist Genomic Region

20656 superoxide dismutase 2, mitochondrial

Details for - - superoxide dismutase 2, mitochondrial

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20656

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
SOX21_HMG_DBD_dimeric_16_1 0.2 0.00000756

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.042 AAGAAAGATNAA NA 190 AAAAGSANTTTC NA

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.22 GCGGAC HINFP1_C2H2_full_monomeric_12_1 1.16 GMCGCGCG Zfp161.1, E2F2.1, E2F3.1, Zfp161.2

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.74 ATGGTGNG mmu-mir-767 7mer_a1 NA NA NA

3p UTR PITA

miRNAs percTargets pValue
mmu-miR-32, mmu-miR-92b, mmu-miR-363, mmu-miR-367, mmu-miR-25, mmu-miR-92a 0.681818 0.0000246

3p UTR TargetScan

miRNAs percTargets pValue
0.26087 0.00000311

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