TargetScan_21 megaCluster: 11 Residual: 0.16

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_21 11 0.16 15 0 0.94754 0

Members

Displaying 1 - 55 of 55
107435 histone aminotransferase 1

Details for - - histone aminotransferase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 107435

Tuberculist Genomic Region

110196 farnesyl diphosphate synthetase

Details for - - farnesyl diphosphate synthetase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 110196

Tuberculist Genomic Region

11799 baculoviral IAP repeat-containing 5

Details for RP23-268N22.2 - baculoviral IAP repeat-containing 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11799

Tuberculist Genomic Region

12442 cyclin B2

Details for - - cyclin B2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12442

Tuberculist Genomic Region

12532 cell division cycle 25C

Details for - - cell division cycle 25C

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12532

Tuberculist Genomic Region

12580 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)

Details for RP23-320F19.3 - cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12580

Tuberculist Genomic Region

14087 Fanconi anemia, complementation group A

Details for - - Fanconi anemia, complementation group A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14087

Tuberculist Genomic Region

15270 H2A histone family, member X

Details for - - H2A histone family, member X

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15270

Tuberculist Genomic Region

16907 lamin B2

Details for - - lamin B2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16907

Tuberculist Genomic Region

170459 StAR-related lipid transfer (START) domain containing 4

Details for - - StAR-related lipid transfer (START) domain containing 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 170459

Tuberculist Genomic Region

17219 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)

Details for - - minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17219

Tuberculist Genomic Region

19362 RAD51 associated protein 1

Details for - - RAD51 associated protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19362

Tuberculist Genomic Region

208836 Fanconi anemia, complementation group I

Details for - - Fanconi anemia, complementation group I

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 208836

Tuberculist Genomic Region

21877 thymidine kinase 1

Details for RP23-151N19.8 - thymidine kinase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 21877

Tuberculist Genomic Region

22171 thymidylate synthase

Details for - - thymidylate synthase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22171

Tuberculist Genomic Region

404710 IQ motif containing GTPase activating protein 3

Details for - - IQ motif containing GTPase activating protein 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 404710

Tuberculist Genomic Region

52033 PDZ binding kinase

Details for - - PDZ binding kinase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 52033

Tuberculist Genomic Region

52276 cell division cycle associated 8

Details for RP23-168M5.8 - cell division cycle associated 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 52276

Tuberculist Genomic Region

56702 histone cluster 1, H1b

Details for RP23-138F20.13-001 - histone cluster 1, H1b

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56702

Tuberculist Genomic Region

59001 polymerase (DNA directed), epsilon 3 (p17 subunit)

Details for RP24-189G18.8 - polymerase (DNA directed), epsilon 3 (p17 subunit)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 59001

Tuberculist Genomic Region

66336 centromere protein P

Details for - - centromere protein P

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66336

Tuberculist Genomic Region

66447 microsomal glutathione S-transferase 3

Details for - - microsomal glutathione S-transferase 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66447

Tuberculist Genomic Region

66570 centromere protein M

Details for - - centromere protein M

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66570

Tuberculist Genomic Region

70024 minichromosome maintenance deficient 10 (S. cerevisiae)

Details for RP23-379M5.1 - minichromosome maintenance deficient 10 (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70024

Tuberculist Genomic Region

70235 POC1 centriolar protein homolog A (Chlamydomonas)

Details for - - POC1 centriolar protein homolog A (Chlamydomonas)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70235

Tuberculist Genomic Region

70454 centromere protein L

Details for - - centromere protein L

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70454

Tuberculist Genomic Region

70466 cytoskeleton associated protein 2-like

Details for RP23-160G19.6 - cytoskeleton associated protein 2-like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70466

Tuberculist Genomic Region

70645 Opa interacting protein 5

Details for RP23-22A15.3 - Opa interacting protein 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70645

Tuberculist Genomic Region

72119 TPX2, microtubule-associated protein homolog (Xenopus laevis)

Details for RP23-414F8.1 - TPX2, microtubule-associated protein homolog (Xenopus laevis)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72119

Tuberculist Genomic Region

77782 polymerase (DNA directed), theta

Details for - - polymerase (DNA directed), theta

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 77782

Tuberculist Genomic Region

107995 cell division cycle 20

Details for RP23-145E1.5 - cell division cycle 20

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 107995

Tuberculist Genomic Region

108912 cell division cycle associated 2

Details for - - cell division cycle associated 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 108912

Tuberculist Genomic Region

110033 kinesin family member 22

Details for - - kinesin family member 22

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 110033

Tuberculist Genomic Region

12449 cyclin F

Details for - - cyclin F

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12449

Tuberculist Genomic Region

14793 cell division cycle associated 3

Details for - - cell division cycle associated 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14793

Tuberculist Genomic Region

16571 kinesin family member 4

Details for RP23-213F21.3 - kinesin family member 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16571

Tuberculist Genomic Region

16906 lamin B1

Details for - - lamin B1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16906

Tuberculist Genomic Region

17279 maternal embryonic leucine zipper kinase

Details for RP23-382O11.1 - maternal embryonic leucine zipper kinase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17279

Tuberculist Genomic Region

18005 NIMA (never in mitosis gene a)-related expressed kinase 2

Details for - - NIMA (never in mitosis gene a)-related expressed kinase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18005

Tuberculist Genomic Region

19348 kinesin family member 20A

Details for - - kinesin family member 20A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19348

Tuberculist Genomic Region

208628 kinetochore associated 1

Details for - - kinetochore associated 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 208628

Tuberculist Genomic Region

20878 aurora kinase A

Details for - - aurora kinase A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20878

Tuberculist Genomic Region

218977 discs, large (Drosophila) homolog-associated protein 5

Details for - - discs, large (Drosophila) homolog-associated protein 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 218977

Tuberculist Genomic Region

22137 Ttk protein kinase

Details for - - Ttk protein kinase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22137

Tuberculist Genomic Region

224171 RIKEN cDNA C330027C09 gene

Details for - - RIKEN cDNA C330027C09 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 224171

Tuberculist Genomic Region

228421 kinesin family member 18A

Details for RP23-206C1.1 - kinesin family member 18A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 228421

Tuberculist Genomic Region

269224 PAS domain containing serine/threonine kinase

Details for - - PAS domain containing serine/threonine kinase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 269224

Tuberculist Genomic Region

56419 diaphanous homolog 3 (Drosophila)

Details for - - diaphanous homolog 3 (Drosophila)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56419

Tuberculist Genomic Region

623474 RAD54 homolog B (S. cerevisiae)

Details for RP23-242O9.3 - RAD54 homolog B (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 623474

Tuberculist Genomic Region

67121 microtubule associated serine/threonine kinase-like

Details for - - microtubule associated serine/threonine kinase-like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67121

Tuberculist Genomic Region

67849 cell division cycle associated 5

Details for - - cell division cycle associated 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67849

Tuberculist Genomic Region

68026 RIKEN cDNA 2810417H13 gene

Details for - - RIKEN cDNA 2810417H13 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68026

Tuberculist Genomic Region

71819 kinesin family member 23

Details for - - kinesin family member 23

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71819

Tuberculist Genomic Region

73804 kinesin family member 2C

Details for RP23-59L24.10-001 - kinesin family member 2C

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 73804

Tuberculist Genomic Region

80986 cytoskeleton associated protein 2

Details for - - cytoskeleton associated protein 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 80986

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
V_NFYA_Q5_M02106 0.6 0.0000000000058

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
2.4e-29 AAAAAAMAAAAA NA 2.8e-21 ARCCAATCASMR NFYA_MA0060.1, Gfi_MA0038.1, V$NFYA_Q5_M02106, V$NFY_01_M00287, V$NFYC_Q5_M02107, V$NFY_Q6_M00185, V$NFY_C_M00209, V$NFY_Q6_01_M00775, V$CAAT_01_M00254, V$ALPHACP1_01_M00687, V$CAAT_C_M00200, V$ACAAT_B_M00309, V$IPF1_02_M01234

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.45 AACGCG NA 1.35 TTGGCGCG V$E2F_Q4_02_M00939, V$E2F_Q3_01_M00918, V$E2F1_Q3_01_M00938, V$E2F_Q2_M00803, V$E2F_Q6_01_M00920, V$E2F_Q4_01_M00919, V$E2F_03_M00516, V$SMAD4_04_M02898, V$E2F2_04_M02846, Smad3.1, E2F2.2, E2F3.2, E2F2.1, Zfp161.1, Bcl6b.2, E2F3.1, Zfp410.1

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.4 CGCGAG NA NA 0.53 GNGACCGG NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
NA

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