TargetScan_22 megaCluster: 5 Residual: 0.24

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_22	5	0.24	15	0	0.903865	0

Members

Displaying 1 - 44 of 44

TFBS DB TF

TFs	percTargets	pValue
V_SP1_Q4_01_M00932	1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000044	AAAACAAAAAAA	NA	0.00077	TKGGGGGCGGGG	SP1_MA0079.2, Klf4_MA0039.2, V$ZFP281_01_M01597, V$SP1_03_M02281, V$SP1_Q2_01_M00933, V$SP1_Q6_M00196, V$SP4_Q5_M01273, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$KLF7_03_M02773, V$ZFP281_04_M02831, V$UF1H3BETA_Q6_M01068, V$SP1_02_M01303, V$GC_01_M00255, V$GKLF_02_M01588, V$EGR1_Q6_M01873, V$BCL6B_04_M02844, V$CKROX_Q2_M01175, V$ZBP89_Q4_M01816, V$SP4_03_M02810, V$KROX_Q6_M00982, V$ZFP740_03_M02834, V$CACD_01_M01113, V$MAZR_01_M00491, V$MAZ_Q6_M00649, V$ZFP410_04_M02936, V$ZNF219_01_M01122, V$EGR1_06_M02744, V$SP1SP3_Q4_M01219, V$SP1_01_M00008, V$WT1_Q6_01_M02036, V$MAZ_Q6_01_M02023, V$KLF15_Q2_M01714, V$CACBINDINGPROTEIN_Q6_M00720, V$SMAD4_04_M02898, V$SP2_01_M01783, V$E2F3_Q6_M02089, V$EKLF_Q5_M01874, V$EGR_Q6_M00807, V$ETF_Q6_M00695, V$MOVOB_01_M01104, V$LRF_Q2_M01100, V$FKLF_Q5_M01837, Klf7.1, Zfp281.2, Bcl6b.2, Sp4.1, Zfp740.1, Zfp410.1, Egr1.1, Smad3.1, Sox13.2, Ascl2.2, Zbtb7b.1, Zif268.1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, SP4_C2H2_full_monomeric_17_1, ZNF740_C2H2_full_monomeric_10_1, KLF14_C2H2_DBD_monomeric_14_1, Klf12_C2H2_DBD_monomeric_15_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.02	GCGGGT	V$GCM1_03_M02758, Gcm1.1, Smad3.1, GCM2_GCM_DBD_monomeric_10_1, GCM1_GCM_DBD_monomeric_10_1, GCM1_GCM_full_monomeric_11_1	1.06	CCCGCTTC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.65	CGCGAA	NA	NA	0.69	TAGCCNCG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

102122 family with sequence similarity 192, member A Details for - - family with sequence similarity 192, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 102122 Tuberculist Genomic Region	103742 migration and invasion enhancer 1 Details for RP23-355L10.9 - migration and invasion enhancer 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 103742 Tuberculist Genomic Region
106025 SHANK-associated RH domain interacting protein Details for - - SHANK-associated RH domain interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106025 Tuberculist Genomic Region	110558 histocompatibility 2, Q region locus 9 Details for - - histocompatibility 2, Q region locus 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110558 Tuberculist Genomic Region
11432 acid phosphatase 2, lysosomal Details for RP23-20F9.7 - acid phosphatase 2, lysosomal GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11432 Tuberculist Genomic Region	12843 collagen, type I, alpha 2 Details for - - collagen, type I, alpha 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12843 Tuberculist Genomic Region
12982 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) Details for - - colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12982 Tuberculist Genomic Region	13179 decorin Details for - - decorin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13179 Tuberculist Genomic Region
13544 dishevelled 3, dsh homolog (Drosophila) Details for - - dishevelled 3, dsh homolog (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13544 Tuberculist Genomic Region	15040 histocompatibility 2, T region locus 23 Details for - - histocompatibility 2, T region locus 23 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15040 Tuberculist Genomic Region
16658 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) Details for RP23-333A18.1 - v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16658 Tuberculist Genomic Region	19018 SCAN domain-containing 1 Details for - - SCAN domain-containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19018 Tuberculist Genomic Region
19158 cytohesin 2 Details for - - cytohesin 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19158 Tuberculist Genomic Region	212772 ADP-ribosylation factor-like 14 effector protein Details for RP23-12N7.2 - ADP-ribosylation factor-like 14 effector protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 212772 Tuberculist Genomic Region
213811 cDNA sequence BC002059 Details for - - cDNA sequence BC002059 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 213811 Tuberculist Genomic Region	21826 thrombospondin 2 Details for - - thrombospondin 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21826 Tuberculist Genomic Region
22318 vesicle-associated membrane protein 2 Details for RP23-26L6.8 - vesicle-associated membrane protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22318 Tuberculist Genomic Region	223774 asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase) Details for - - asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 223774 Tuberculist Genomic Region
225010 lysocardiolipin acyltransferase 1 Details for RP23-294D3.1 - lysocardiolipin acyltransferase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225010 Tuberculist Genomic Region	233065 alkB, alkylation repair homolog 6 (E. coli) Details for - - alkB, alkylation repair homolog 6 (E. coli) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 233065 Tuberculist Genomic Region
233900 ring finger protein 40 Details for - - ring finger protein 40 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 233900 Tuberculist Genomic Region	243371 leucine rich repeat containing 61 Details for - - leucine rich repeat containing 61 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 243371 Tuberculist Genomic Region
26446 proteasome (prosome, macropain) subunit, beta type 3 Details for RP23-94N18.8 - proteasome (prosome, macropain) subunit, beta type 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26446 Tuberculist Genomic Region	30839 F-box and WD-40 domain protein 5 Details for RP23-47P18.14-001 - F-box and WD-40 domain protein 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 30839 Tuberculist Genomic Region
320634 oculocerebrorenal syndrome of Lowe Details for RP23-455F14.2 - oculocerebrorenal syndrome of Lowe GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320634 Tuberculist Genomic Region	328833 triggering receptor expressed on myeloid cells-like 2 Details for - - triggering receptor expressed on myeloid cells-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 328833 Tuberculist Genomic Region
66079 transmembrane protein 42 Details for - - transmembrane protein 42 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66079 Tuberculist Genomic Region	66218 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9 Details for - - NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66218 Tuberculist Genomic Region
66278 small integral membrane protein 20 Details for - - small integral membrane protein 20 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66278 Tuberculist Genomic Region	66610 ABI gene family, member 3 Details for RP23-151M22.4 - ABI gene family, member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66610 Tuberculist Genomic Region
72324 plexin domain containing 1 Details for RP23-309H19.1 - plexin domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72324 Tuberculist Genomic Region	74211 RIKEN cDNA 1700017B05 gene Details for - - RIKEN cDNA 1700017B05 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74211 Tuberculist Genomic Region
74257 tetraspanin 17 Details for - - tetraspanin 17 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74257 Tuberculist Genomic Region	76633 RIKEN cDNA 1700112E06 gene Details for - - RIKEN cDNA 1700112E06 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76633 Tuberculist Genomic Region
78611 BTB (POZ) domain containing 19 Details for RP23-59L24.3 - BTB (POZ) domain containing 19 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78611 Tuberculist Genomic Region	80517 HERPUD family member 2 Details for MNCb-2040 - HERPUD family member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80517 Tuberculist Genomic Region
81897 toll-like receptor 9 Details for - - toll-like receptor 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 81897 Tuberculist Genomic Region	27226 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) Details for - - phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27226 Tuberculist Genomic Region
70240 UFM1-specific peptidase 1 Details for - - UFM1-specific peptidase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70240 Tuberculist Genomic Region	99543 olfactomedin-like 3 Details for DN-252N9.4 - olfactomedin-like 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99543 Tuberculist Genomic Region
106338 NOL1/NOP2/Sun domain family member 3 Details for - - NOL1/NOP2/Sun domain family member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106338 Tuberculist Genomic Region	20304 chemokine (C-C motif) ligand 5 Details for RP23-320E6.2 - chemokine (C-C motif) ligand 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20304 Tuberculist Genomic Region
217119 xylosyltransferase II Details for RP23-290B5.5 - xylosyltransferase II GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217119 Tuberculist Genomic Region	71772 phospholipase B domain containing 2 Details for - - phospholipase B domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71772 Tuberculist Genomic Region

TargetScan_22 megaCluster: 5 Residual: 0.24

Summary

Members

Details for - - family with sequence similarity 192, member A

Details for RP23-355L10.9 - migration and invasion enhancer 1

Details for - - SHANK-associated RH domain interacting protein

Details for - - histocompatibility 2, Q region locus 9

Details for RP23-20F9.7 - acid phosphatase 2, lysosomal

Details for - - collagen, type I, alpha 2

Details for - - colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)

Details for - - decorin

Details for - - dishevelled 3, dsh homolog (Drosophila)

Details for - - histocompatibility 2, T region locus 23

Details for RP23-333A18.1 - v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)

Details for - - SCAN domain-containing 1

Details for - - cytohesin 2

Details for RP23-12N7.2 - ADP-ribosylation factor-like 14 effector protein

Details for - - cDNA sequence BC002059

Details for - - thrombospondin 2

Details for RP23-26L6.8 - vesicle-associated membrane protein 2

Details for - - asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase)

Details for RP23-294D3.1 - lysocardiolipin acyltransferase 1

Details for - - alkB, alkylation repair homolog 6 (E. coli)

Details for - - ring finger protein 40

Details for - - leucine rich repeat containing 61

Details for RP23-94N18.8 - proteasome (prosome, macropain) subunit, beta type 3

Details for RP23-47P18.14-001 - F-box and WD-40 domain protein 5

Details for RP23-455F14.2 - oculocerebrorenal syndrome of Lowe

Details for - - triggering receptor expressed on myeloid cells-like 2

Details for - - transmembrane protein 42

Details for - - NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9

Details for - - small integral membrane protein 20

Details for RP23-151M22.4 - ABI gene family, member 3

Details for RP23-309H19.1 - plexin domain containing 1

Details for - - RIKEN cDNA 1700017B05 gene

Details for - - tetraspanin 17

Details for - - RIKEN cDNA 1700112E06 gene

Details for RP23-59L24.3 - BTB (POZ) domain containing 19

Details for MNCb-2040 - HERPUD family member 2

Details for - - toll-like receptor 9

Details for - - phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

Details for - - UFM1-specific peptidase 1

Details for DN-252N9.4 - olfactomedin-like 3

Details for - - NOL1/NOP2/Sun domain family member 3

Details for RP23-320E6.2 - chemokine (C-C motif) ligand 5

Details for RP23-290B5.5 - xylosyltransferase II

Details for - - phospholipase B domain containing 2

GO Terms

3p UTR PITA