TargetScan_223 megaCluster: 1 Residual: 0.30 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_223	1	0.30	12	0	0.809184	0.003

Members

Displaying 1 - 33 of 33

100019 midasin homolog (yeast) Details for - - midasin homolog (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100019 Tuberculist Genomic Region	16153 ras homolog gene family, member C Details for - - ras homolog gene family, member C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11853 Tuberculist Genomic Region
20529 PR domain containing 1, with ZNF domain Details for - - PR domain containing 1, with ZNF domain GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12142 Tuberculist Genomic Region	20715 interleukin 10 Details for AL513351.1 - interleukin 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16153 Tuberculist Genomic Region
208449 solute carrier family 31, member 1 Details for RP24-145P21.1 - solute carrier family 31, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20529 Tuberculist Genomic Region	209645 serine (or cysteine) peptidase inhibitor, clade A, member 3G Details for - - serine (or cysteine) peptidase inhibitor, clade A, member 3G GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20715 Tuberculist Genomic Region
21426 sphingomyelin synthase 1 Details for - - sphingomyelin synthase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 208449 Tuberculist Genomic Region	21817 BEN domain containing 7 Details for RP23-198G1.1 - BEN domain containing 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209645 Tuberculist Genomic Region
22793 transcription factor EC Details for - - transcription factor EC GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21426 Tuberculist Genomic Region	230157 transglutaminase 2, C polypeptide Details for RP23-396G1.2 - transglutaminase 2, C polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21817 Tuberculist Genomic Region
234135 zyxin Details for - - zyxin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22793 Tuberculist Genomic Region	23959 transmembrane protein with EGF-like and two follistatin-like domains 1 Details for RP23-141C15.2 - transmembrane protein with EGF-like and two follistatin-like domains 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230157 Tuberculist Genomic Region
240672 Wolf-Hirschhorn syndrome candidate 1-like 1 (human) Details for - - Wolf-Hirschhorn syndrome candidate 1-like 1 (human) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234135 Tuberculist Genomic Region	241694 5' nucleotidase, ecto Details for - - 5' nucleotidase, ecto GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23959 Tuberculist Genomic Region
246198 dual specificity phosphatase 5 Details for - - dual specificity phosphatase 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240672 Tuberculist Genomic Region	26921 Ral GTPase activating protein, alpha subunit 2 (catalytic) Details for RP23-185F7.2 - Ral GTPase activating protein, alpha subunit 2 (catalytic) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241694 Tuberculist Genomic Region
320509 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 Details for RP23-94N18.5 - myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 246198 Tuberculist Genomic Region	52398 mitogen-activated protein kinase kinase kinase kinase 4 Details for - - mitogen-activated protein kinase kinase kinase kinase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26921 Tuberculist Genomic Region
71648 RIKEN cDNA 9930022D16 gene Details for RP23-465A12.2 - RIKEN cDNA 9930022D16 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320509 Tuberculist Genomic Region	72925 septin 11 Details for - - septin 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52398 Tuberculist Genomic Region
80914 optineurin Details for RP23-379M5.2 - optineurin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71648 Tuberculist Genomic Region	93730 membrane-associated ring finger (C3HC4) 1 Details for - - membrane-associated ring finger (C3HC4) 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72925 Tuberculist Genomic Region
98402 uridine-cytidine kinase 2 Details for - - uridine-cytidine kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80914 Tuberculist Genomic Region	17295 leucine zipper transcription factor-like 1 Details for - - leucine zipper transcription factor-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 93730 Tuberculist Genomic Region
239122 SH3-domain binding protein 4 Details for - - SH3-domain binding protein 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 98402 Tuberculist Genomic Region	240665 met proto-oncogene Details for - - met proto-oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17295 Tuberculist Genomic Region
434204 SET domain, bifurcated 2 Details for mCG_13852 - SET domain, bifurcated 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 239122 Tuberculist Genomic Region	55932 cyclin J Details for - - cyclin J GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240665 Tuberculist Genomic Region
17948 WAS protein homolog associated with actin, golgi membranes and microtubules Details for - - WAS protein homolog associated with actin, golgi membranes and microtubules GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 434204 Tuberculist Genomic Region	245126 guanylate binding protein 3 Details for - - guanylate binding protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 55932 Tuberculist Genomic Region
68732 NLR family, apoptosis inhibitory protein 2 Details for RP23-333E24.2 - NLR family, apoptosis inhibitory protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17948 Tuberculist Genomic Region	Details for - - T cell-interacting, activating receptor on myeloid cells 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245126 Tuberculist Genomic Region
Details for RP23-462P2.7 - leucine rich repeat containing 16A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68732 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
RELA_MA0107.1	0.4375	0.000000273

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
150	GGGGGGNGGGG	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$ZFP281_01_M01597, V$SP4_Q5_M01273, V$SP1_02_M01303, V$SP1_Q2_01_M00933, V$SP1_03_M02281, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$ZFP281_04_M02831, V$UF1H3BETA_Q6_M01068, V$GKLF_02_M01588, V$MAZR_01_M00491, V$KLF7_03_M02773, V$CKROX_Q2_M01175, V$ZBP89_Q4_M01816, V$GC_01_M00255, V$SP1SP3_Q4_M01219, V$ZNF219_01_M01122, V$MAZ_Q6_M00649, V$MAZ_Q6_01_M02023, V$SP4_03_M02810, V$CACD_01_M01113, V$ZFP740_03_M02834, V$KROX_Q6_M00982, V$KLF15_Q2_M01714, V$EKLF_Q5_M01874, V$SP1_01_M00008, V$BCL6B_04_M02844, V$FKLF_Q5_M01837, V$EGR1_Q6_M01873, V$ETF_Q6_M00695, V$EGR1_06_M02744, V$CACBINDINGPROTEIN_Q6_M00720, V$SMAD4_04_M02898, V$SP2_01_M01783, V$WT1_Q6_01_M02036, V$E2F3_Q6_M02089, V$CACCCBINDINGFACTOR_Q6_M00721, V$WT1_Q6_M01118, V$ZFP410_04_M02936, V$MZF1_01_M00083, V$EGR2_Q6_M02092, Zfp281.2, Klf7.1, Sp4.1, Zfp740.1, Bcl6b.2, Egr1.1, Smad3.1, Zfp410.1, Ascl2.2, Zbtb7b.1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, SP8_C2H2_DBD_monomeric_12_1, SP4_C2H2_full_monomeric_17_1, SP3_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, Klf12_C2H2_DBD_monomeric_15_1, Zfp740_C2H2_DBD_monomeric_10_1	4.6	GCSSCGSGCTSC	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.43	GNCGCG	Zfp161.2, Max.2	1.51	NCGGCGCC	V$E2F2_04_M02846, V$E2F4_04_M02847, E2F2.2, E2F3.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.82	ANNTAAGA	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-193b, mmu-miR-193	0.703704	0.00000163

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-329	0.407407	0.0000421

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