TargetScan_28 megaCluster: 10 Residual: 0.15 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_28	10	0.15	15	0	0.961676	0

Members

Displaying 1 - 25 of 25

106344 replication factor C (activator 1) 4 Details for - - replication factor C (activator 1) 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106344 Tuberculist Genomic Region	12419 chromobox 5 Details for - - chromobox 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12419 Tuberculist Genomic Region
12566 cyclin-dependent kinase 2 Details for - - cyclin-dependent kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12566 Tuberculist Genomic Region	13006 structural maintenance of chromosomes 3 Details for - - structural maintenance of chromosomes 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13006 Tuberculist Genomic Region
170439 ELOVL family member 6, elongation of long chain fatty acids (yeast) Details for - - ELOVL family member 6, elongation of long chain fatty acids (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170439 Tuberculist Genomic Region	18969 polymerase (DNA directed), alpha 2 Details for - - polymerase (DNA directed), alpha 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18969 Tuberculist Genomic Region
207818 small cell adhesion glycoprotein Details for - - small cell adhesion glycoprotein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 207818 Tuberculist Genomic Region	217653 MIS18 binding protein 1 Details for - - MIS18 binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217653 Tuberculist Genomic Region
219072 HAUS augmin-like complex, subunit 4 Details for - - HAUS augmin-like complex, subunit 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 219072 Tuberculist Genomic Region	22017 thiopurine methyltransferase Details for - - thiopurine methyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22017 Tuberculist Genomic Region
269702 M-phase phosphoprotein 9 Details for - - M-phase phosphoprotein 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269702 Tuberculist Genomic Region	66531 COX assembly mitochondrial protein 2 Details for - - COX assembly mitochondrial protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66531 Tuberculist Genomic Region
67276 exoribonuclease 1 Details for - - exoribonuclease 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67276 Tuberculist Genomic Region	69723 RPA interacting protein Details for DN-393H17.1 - RPA interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69723 Tuberculist Genomic Region
72787 NDC1 transmembrane nucleoporin Details for RP23-392J14.4 - NDC1 transmembrane nucleoporin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72787 Tuberculist Genomic Region	78658 non-SMC condensin II complex, subunit D3 Details for - - non-SMC condensin II complex, subunit D3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78658 Tuberculist Genomic Region
109232 saccharopine dehydrogenase (putative) Details for - - saccharopine dehydrogenase (putative) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109232 Tuberculist Genomic Region	14056 enhancer of zeste homolog 2 (Drosophila) Details for - - enhancer of zeste homolog 2 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14056 Tuberculist Genomic Region
17216 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) Details for - - minichromosome maintenance deficient 2 mitotin (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17216 Tuberculist Genomic Region	17864 myeloblastosis oncogene-like 1 Details for - - myeloblastosis oncogene-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17864 Tuberculist Genomic Region
18968 polymerase (DNA directed), alpha 1 Details for RP23-53K18.2 - polymerase (DNA directed), alpha 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18968 Tuberculist Genomic Region	218973 WD repeat and HMG-box DNA binding protein 1 Details for - - WD repeat and HMG-box DNA binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 218973 Tuberculist Genomic Region
328186 predicted gene 10336 Details for - - predicted gene 10336 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 328186 Tuberculist Genomic Region	70472 ATPase family, AAA domain containing 2 Details for - - ATPase family, AAA domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70472 Tuberculist Genomic Region
75216 centrosomal protein 128 Details for - - centrosomal protein 128 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75216 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_SP1_Q6_01_M00931, V_GC_01_M00255, V_SP4_Q5_M01273, V_ZFP281_01_M01597, V_SP1_Q2_01_M00933, V_SP1_Q4_01_M00932	1, 1, 1, 1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000047	AAARAAAGAAAA	NA	0.75	RGGCCCCGCCC	Klf4_MA0039.2, SP1_MA0079.2, V$SP4_Q5_M01273, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$KLF7_03_M02773, V$SP1_02_M01303, V$GC_01_M00255, V$GKLF_02_M01588, V$SP1_Q2_01_M00933, V$MAZR_01_M00491, V$CKROX_Q2_M01175, V$SP2_01_M01783, V$SP4_03_M02810, V$ZFP281_01_M01597, V$UF1H3BETA_Q6_M01068, V$E2F3_Q6_M02089, V$SP1_01_M00008, V$CACD_01_M01113, V$SP1_03_M02281, V$SMAD4_04_M02898, V$MAZ_Q6_M00649, V$SP4_04_M02914, V$EGR1_06_M02744, V$KROX_Q6_M00982, V$EGR1_Q6_M01873, V$ZFP281_04_M02831, V$BCL6B_04_M02844, V$CACCCBINDINGFACTOR_Q6_M00721, V$ZBP89_Q4_M01816, V$EKLF_Q5_M01874, V$ZFP740_03_M02834, Klf7.1, Sp4.1, Smad3.1, Egr1.1, Sp4.2, Zfp281.2, Bcl6b.2, Zfp740.1, Zif268.1, Zfp410.1, Klf7.2, Ascl2.2, Sox13.2, Zbtb7b.1, Glis2.1, Zfp740.2, E2F3.1, Klf12_C2H2_DBD_monomeric_15_1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, KLF13_C2H2_full_monomeric_18_1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.57	TCCCGC	V$SP2_01_M01783, V$E2F4_Q6_M02090, Smad3.1	1.91	GCGGGAAC	GCM1_GCM_full_monomeric_11_1

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.6	TATAAC	NA	NA	0.84	ANNACTAA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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