TargetScan_5 megaCluster: 2 Residual: 0.11 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_5	2	0.11	15	0.003	0.977474	0

Members

Displaying 1 - 28 of 28

11541 adenosine A2b receptor Details for RP23-330N10.1 - adenosine A2b receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11541 Tuberculist Genomic Region	12515 CD69 antigen Details for - - CD69 antigen GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12515 Tuberculist Genomic Region
13163 Fas death domain-associated protein Details for - - Fas death domain-associated protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13163 Tuberculist Genomic Region	14469 guanylate binding protein 2 Details for - - guanylate binding protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14469 Tuberculist Genomic Region
14745 lysophosphatidic acid receptor 1 Details for RP23-170A3.2 - lysophosphatidic acid receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14745 Tuberculist Genomic Region	17295 met proto-oncogene Details for - - met proto-oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17295 Tuberculist Genomic Region
22035 tumor necrosis factor (ligand) superfamily, member 10 Details for - - tumor necrosis factor (ligand) superfamily, member 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22035 Tuberculist Genomic Region	230779 serine incorporator 2 Details for RP23-12J1.7 - serine incorporator 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230779 Tuberculist Genomic Region
234311 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 Details for - - DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234311 Tuberculist Genomic Region	245126 T cell-interacting, activating receptor on myeloid cells 1 Details for - - T cell-interacting, activating receptor on myeloid cells 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245126 Tuberculist Genomic Region
30805 solute carrier family 22 (organic cation transporter), member 4 Details for RP23-354D12.1 - solute carrier family 22 (organic cation transporter), member 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 30805 Tuberculist Genomic Region	66674 SPRY domain containing 7 Details for RP23-38F20.1 - SPRY domain containing 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66674 Tuberculist Genomic Region
666907 membrane-spanning 4-domains, subfamily A, member 4A Details for - - membrane-spanning 4-domains, subfamily A, member 4A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 666907 Tuberculist Genomic Region	71371 AT rich interactive domain 5B (MRF1-like) Details for - - AT rich interactive domain 5B (MRF1-like) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71371 Tuberculist Genomic Region
74646 splA/ryanodine receptor domain and SOCS box containing 1 Details for RP23-169H13.1 - splA/ryanodine receptor domain and SOCS box containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74646 Tuberculist Genomic Region	80285 poly (ADP-ribose) polymerase family, member 9 Details for - - poly (ADP-ribose) polymerase family, member 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80285 Tuberculist Genomic Region
100043424 predicted gene 14005 Details for - - predicted gene 14005 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100043424 Tuberculist Genomic Region	11988 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 Details for - - solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11988 Tuberculist Genomic Region
14733 glypican 1 Details for - - glypican 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14733 Tuberculist Genomic Region	17857 myxovirus (influenza virus) resistance 1 Details for - - myxovirus (influenza virus) resistance 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17857 Tuberculist Genomic Region
18037 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18037 Tuberculist Genomic Region	22782 solute carrier family 30 (zinc transporter), member 1 Details for - - solute carrier family 30 (zinc transporter), member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22782 Tuberculist Genomic Region
229003 helicase with zinc finger 2, transcriptional coactivator Details for RP23-401M24.3 - helicase with zinc finger 2, transcriptional coactivator GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229003 Tuberculist Genomic Region	229900 guanylate binding protein 7 Details for - - guanylate binding protein 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229900 Tuberculist Genomic Region
55932 guanylate binding protein 3 Details for - - guanylate binding protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 55932 Tuberculist Genomic Region	628693 predicted gene 6904 Details for mCG_6143 - predicted gene 6904 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 628693 Tuberculist Genomic Region
70617 RIKEN cDNA 5730508B09 gene Details for - - RIKEN cDNA 5730508B09 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70617 Tuberculist Genomic Region	99382 ankyrin repeat and BTB (POZ) domain containing 2 Details for RP23-338B23.1 - ankyrin repeat and BTB (POZ) domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99382 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_ISGF3G_03_M02771	0.423077	0.00000000000595

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000014	AGTTTCNNTTTC	STAT1_MA0137.1, IRF1_MA0050.1, IRF2_MA0051.1, V$ISRE_01_M00258, V$ICSBP_Q6_M00699, V$IRF_Q6_M00772, V$IRF2_Q6_M01882, V$IRF_Q6_01_M00972, V$ISGF3G_03_M02771, V$IRF1_Q6_01_M01881, V$IRF1_01_M00062, V$IRF8_Q6_M01665, V$IRF2_01_M00063, V$IRF3_05_M02767, V$IRF7_01_M00453, V$IRF3_Q3_M01279, V$IRF5_03_M02769, V$BLIMP1_Q6_M01066, Isgf3g.1, Irf3.1, Irf5.2, IRF7_IRF_DBD_dimeric_14_1, IRF8_IRF_full_dimeric_14_1, IRF9_IRF_full_trimeric_15_1, IRF4_IRF_full_dimeric_15_1, IRF3_IRF_full_trimeric_21_1, PRDM1_C2H2_full_monomeric-or-dimeric_15_1, IRF5_IRF_full_dimeric_14_1, IRF7_IRF_DBD_trimeric_17_1	0.13	CTTTYYCTTYTC	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
0.84	GCGGTC	NA	1.03	AGCGGCTT	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.56	ATCAAC	NA	NA	0.7	AANGACTG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-669m-3p	0.571429	0.0000192

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