TargetScan_79 megaCluster: 4 Residual: 0.24 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_79	4	0.24	15	0	0.884918	0

Members

Displaying 1 - 34 of 34

100302498 small nucleolar RNA, H/ACA box 21 Details for - - small nucleolar RNA, H/ACA box 21 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100302498 Tuberculist Genomic Region	100503054 predicted gene, 19528 Details for - - predicted gene, 19528 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503054 Tuberculist Genomic Region
170758 membrane-spanning 4-domains, subfamily A, member 7 Details for - - membrane-spanning 4-domains, subfamily A, member 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109225 Tuberculist Genomic Region	192195 RAS-related C3 botulinum substrate 3 Details for RP23-84C12.18-001 - RAS-related C3 botulinum substrate 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170758 Tuberculist Genomic Region
19697 ash1 (absent, small, or homeotic)-like (Drosophila) Details for - - ash1 (absent, small, or homeotic)-like (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 192195 Tuberculist Genomic Region	20288 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Details for - - v-rel reticuloendotheliosis viral oncogene homolog A (avian) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19697 Tuberculist Genomic Region
20375 macrophage scavenger receptor 1 Details for - - macrophage scavenger receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20288 Tuberculist Genomic Region	237928 spleen focus forming virus (SFFV) proviral integration oncogene Details for RP23-20F9.1 - spleen focus forming virus (SFFV) proviral integration oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20375 Tuberculist Genomic Region
23983 phosphatase, orphan 1 Details for RP23-151M22.3 - phosphatase, orphan 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 237928 Tuberculist Genomic Region	434394 poly(rC) binding protein 1 Details for - - poly(rC) binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23983 Tuberculist Genomic Region
52348 ribosomal protein L36 pseudogene Details for - - ribosomal protein L36 pseudogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 434394 Tuberculist Genomic Region	623174 vacuolar protein sorting 37A (yeast) Details for - - vacuolar protein sorting 37A (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52348 Tuberculist Genomic Region
66889 predicted gene 6404 Details for - - predicted gene 6404 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 623174 Tuberculist Genomic Region	71398 ring finger protein 128 Details for MNCb-3816 - ring finger protein 128 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66889 Tuberculist Genomic Region
74277 RIKEN cDNA 5430427O19 gene Details for RP23-311G7.1 - RIKEN cDNA 5430427O19 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71398 Tuberculist Genomic Region	99334 cysteine-rich hydrophobic domain 2 Details for - - cysteine-rich hydrophobic domain 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74277 Tuberculist Genomic Region
100217461 zinc finger SCAN domains 29 Details for RP23-232N20.4 - zinc finger SCAN domains 29 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99334 Tuberculist Genomic Region	12042 small nucleolar RNA, C/D box 89 Details for - - small nucleolar RNA, C/D box 89 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100217461 Tuberculist Genomic Region
13000 B cell leukemia/lymphoma 10 Details for - - B cell leukemia/lymphoma 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12042 Tuberculist Genomic Region	17390 casein kinase 2, alpha prime polypeptide Details for - - casein kinase 2, alpha prime polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13000 Tuberculist Genomic Region
18689 matrix metallopeptidase 2 Details for - - matrix metallopeptidase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17390 Tuberculist Genomic Region	18787 per-hexamer repeat gene 4 Details for - - per-hexamer repeat gene 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18689 Tuberculist Genomic Region
192657 serine (or cysteine) peptidase inhibitor, clade E, member 1 Details for - - serine (or cysteine) peptidase inhibitor, clade E, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18787 Tuberculist Genomic Region	194744 elongation factor RNA polymerase II 2 Details for - - elongation factor RNA polymerase II 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 192657 Tuberculist Genomic Region
21353 solute carrier family 25, member 43 Details for RP23-100G16.4 - solute carrier family 25, member 43 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 194744 Tuberculist Genomic Region	216080 TRAF family member-associated Nf-kappa B activator Details for RP23-1O11.1 - TRAF family member-associated Nf-kappa B activator GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21353 Tuberculist Genomic Region
225929 ubiquitin-conjugating enzyme E2D 1 Details for - - ubiquitin-conjugating enzyme E2D 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216080 Tuberculist Genomic Region	228543 protein associated with topoisomerase II homolog 1 (yeast) Details for - - protein associated with topoisomerase II homolog 1 (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225929 Tuberculist Genomic Region
56274 ras homolog gene family, member V Details for RP23-46P4.4 - ras homolog gene family, member V GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228543 Tuberculist Genomic Region	67154 serine/threonine kinase 3 Details for - - serine/threonine kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56274 Tuberculist Genomic Region
94352 metadherin Details for - - metadherin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67154 Tuberculist Genomic Region	100502606 lysyl oxidase-like 2 Details for - - lysyl oxidase-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 94352 Tuberculist Genomic Region
102857 predicted gene, 19279 Details for - - predicted gene, 19279 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100502606 Tuberculist Genomic Region	Details for RP23-329M9.4 - solute carrier family 6 (neurotransmitter transporter, creatine), member 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 102857 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
NA

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0012	TTTTTTTTYNTG	NA	130000	GGKGGGCGGGGC	Klf4_MA0039.2, SP1_MA0079.2, V$SP4_Q5_M01273, V$GKLF_02_M01588, V$SP1_Q4_01_M00932, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$SP1_Q2_01_M00933, V$KLF7_03_M02773, V$SP1_03_M02281, V$ZFP281_01_M01597, V$GC_01_M00255, V$SP1_02_M01303, V$UF1H3BETA_Q6_M01068, V$MAZR_01_M00491, V$ZNF219_01_M01122, V$CKROX_Q2_M01175, V$ZBP89_Q4_M01816, V$SP2_01_M01783, V$EKLF_Q5_M01874, V$MAZ_Q6_M00649, V$CACD_01_M01113, V$ZFP281_04_M02831, V$SP1SP3_Q4_M01219, V$MAZ_Q6_01_M02023, V$ZFP740_03_M02834, V$GLI3_Q5_01_M01657, V$SP4_03_M02810, V$SMAD4_04_M02898, V$CACCCBINDINGFACTOR_Q6_M00721, V$EGR_Q6_M00807, V$E2F3_Q6_M02089, V$GLI3_01_M01596, V$EGR1_Q6_M01873, V$ZNF515_01_M01231, V$KLF15_Q2_M01714, V$SP1_01_M00008, V$WT1_Q6_M01118, V$KROX_Q6_M00982, V$EGR2_Q6_M02092, V$CACBINDINGPROTEIN_Q6_M00720, V$BCL6B_04_M02844, V$WT1_Q6_01_M02036, V$EGR1_06_M02744, V$FKLF_Q5_M01837, Klf7.1, Zfp281.2, Zfp740.1, Smad3.1, Sp4.1, Egr1.1, Bcl6b.2, Sox13.2, Ascl2.2, Egr1.2, Zbtb7b.1, Zfp410.1, Glis2.1, Zif268.1, SP1_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP8_C2H2_DBD_monomeric_12_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1, KLF14_C2H2_DBD_monomeric_14_1, Zfp740_C2H2_DBD_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
0.98	TCGCGG	NA	1.23	CCGCCGCG	V$ETF_Q6_M00695, Zfp410.1, Bcl6b.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.59	CGCTCG	NA	NA	0.78	CAAACTTT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-224	0.565217	0.00000146

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