Methanococcus maripaludis S2 Module 1 Residual: 0.42

Residual: 0.42 Score: -10.8624 version: mmp_cmonkey_11_Oct_11
MMP0153 2-oxosuberate synthase, first step (NCBI)

Details for MMP0153 - 2-oxosuberate synthase, first step (NCBI)

GO Terms: GO:0019752, GO:0003852, GO:0046912

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0153

Tuberculist Genomic Region

MMP1140 ferredoxin (NCBI)

Details for MMP1140 - ferredoxin (NCBI)

GO Terms: GO:0006118, GO:0051536, GO:0009055

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1140

Tuberculist Genomic Region

MMP0154 conserved hypothetical archaeal protein (NCBI)

Details for MMP0154 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0154

Tuberculist Genomic Region

MMP1185 Hydrogen uptake protein:Hydrogenase maturation protease HycI (NCBI)

Details for MMP1185 - Hydrogen uptake protein:Hydrogenase maturation protease HycI (NCBI)

GO Terms: GO:0008047, GO:0008233

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1185

Tuberculist Genomic Region

MMP0166 MatE family member (drug/sodium antiporters) (NCBI)

Details for MMP0166 - MatE family member (drug/sodium antiporters) (NCBI)

GO Terms: GO:0006855, GO:0016020, GO:0015238, GO:0015297

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0166

Tuberculist Genomic Region

MMP1238 TonB-dependent receptor protein:Biotin synthase (NCBI)

Details for MMP1238 - TonB-dependent receptor protein:Biotin synthase (NCBI)

GO Terms: GO:0009102, GO:0051536, GO:0004076

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1238

Tuberculist Genomic Region

MMP0167 ABC transporter ATP binding protein family member (NCBI)

Details for MMP0167 - ABC transporter ATP binding protein family member (NCBI)

GO Terms: GO:0005524, GO:0016887

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0167

Tuberculist Genomic Region

MMP1240 conserved hypothetical protein (NCBI)

Details for MMP1240 - conserved hypothetical protein (NCBI)

GO Terms: GO:0009058, GO:0030170, GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1240

Tuberculist Genomic Region

MMP0168 Transcriptional regulator PadR-like family (NCBI)

Details for MMP0168 - Transcriptional regulator PadR-like family (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0168

Tuberculist Genomic Region

MMP1550 NADP oxidoreductase, coenzyme F420-dependent (NCBI)

Details for MMP1550 - NADP oxidoreductase, coenzyme F420-dependent (NCBI)

GO Terms: GO:0006118

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1550

Tuberculist Genomic Region

MMP0176 CDC48 cell division cycle protein family member (NCBI)

Details for MMP0176 - CDC48 cell division cycle protein family member (NCBI)

GO Terms: GO:0001906, GO:0006310, GO:0006281, GO:0005634, GO:0005524, GO:0009378, GO:0017111

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0176

Tuberculist Genomic Region

MMP1606 Flavoprotein:DNA/pantothenate metabolism flavoprotein (NCBI)

Details for MMP1606 - Flavoprotein:DNA/pantothenate metabolism flavoprotein (NCBI)

GO Terms: GO:0004633, GO:0004632

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1606

Tuberculist Genomic Region

MMP0239 conserved hypothetical archaeal protein (NCBI)

Details for MMP0239 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0239

Tuberculist Genomic Region

MMP0180 riboflavin synthase (NCBI)

Details for MMP0180 - riboflavin synthase (NCBI)

GO Terms: GO:0009231, GO:0009349, GO:0004746

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0180

Tuberculist Genomic Region

MMP0450 ferredoxin (NCBI)

Details for MMP0450 - ferredoxin (NCBI)

GO Terms: GO:0006118, GO:0009236, GO:0051536, GO:0009055, GO:0042242

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0450

Tuberculist Genomic Region

MMP1071 conserved hypothetical archaeal protein (NCBI)

Details for MMP1071 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1071

Tuberculist Genomic Region

MMP0451 conserved hypothetical protein (NCBI)

Details for MMP0451 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0451

Tuberculist Genomic Region

MMP1072 Aminotransferase (subgroup I) similar to Aromatic Aminotransferase (NCBI)

Details for MMP1072 - Aminotransferase (subgroup I) similar to Aromatic Aminotransferase (NCBI)

GO Terms: GO:0009058, GO:0004069, GO:0016847, GO:0030170

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1072

Tuberculist Genomic Region

MMP0536 conserved hypothetical protein (NCBI)

Details for MMP0536 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0536

Tuberculist Genomic Region

MMP0119 Biotin--protein ligase (NCBI)

Details for MMP0119 - Biotin--protein ligase (NCBI)

GO Terms: GO:0006464, GO:0004077

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0119

Tuberculist Genomic Region

MMP0608 2-hydroxyglutaryl-CoA dehydratase (Component A) related protein (NCBI)

Details for MMP0608 - 2-hydroxyglutaryl-CoA dehydratase (Component A) related protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0608

Tuberculist Genomic Region

MMP1241 conserved hypothetical protein (NCBI)

Details for MMP1241 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1241

Tuberculist Genomic Region

MMP0685 SAM (and some other nucleotide) binding motif:N-6 Adenine-specific DNA methylase (NCBI)

Details for MMP0685 - SAM (and some other nucleotide) binding motif:N-6 Adenine-specific DNA methylase (NCBI)

GO Terms: GO:0006479, GO:0005737, GO:0008276, GO:0003676

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0685

Tuberculist Genomic Region

MMP1549 AP endonuclease, family 2 (NCBI)

Details for MMP1549 - AP endonuclease, family 2 (NCBI)

GO Terms: GO:0006281, GO:0005622, GO:0003677, GO:0004519

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1549

Tuberculist Genomic Region

MMP0876 FO synthase, subunit CofG (NCBI)

Details for MMP0876 - FO synthase, subunit CofG (NCBI)

GO Terms: GO:0008152, GO:0003824, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0876

Tuberculist Genomic Region

MMP1605 Pyruvate kinase (NCBI)

Details for MMP1605 - Pyruvate kinase (NCBI)

GO Terms: GO:0006096, GO:0030955, GO:0000287, GO:0004743

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1605

Tuberculist Genomic Region

Motif 1: e-value: 30 e-value: 7600
Regulator Interaction Influence Weight Other Influences
ArsR family member (NCBI)
TATA-binding protein (TBP) (NCBI)
up-regulates 0.25
Cro repressor family Helix-turn-helix motif containing protein (NCBI)
up-regulates 0.18
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0051536 iron-sulfur cluster binding 67 1.13 4 0.0200
MF GO:0051540 metal cluster binding 67 1.13 4 0.0200
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