Methanococcus maripaludis S2 Module 7 Residual: 0.32

Residual: 0.32 Score: -15.7219 version: mmp_cmonkey_11_Oct_11
MMP0080 glutamate synthase; large subunit; archaeal subunit 1 (NCBI)

Details for MMP0080 - glutamate synthase; large subunit; archaeal subunit 1 (NCBI)

GO Terms: GO:0009113, GO:0009342, GO:0004044, GO:0004355

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0080

Tuberculist Genomic Region

MMP0947 ATP phosphoribosyltransferase (NCBI)

Details for MMP0947 - ATP phosphoribosyltransferase (NCBI)

GO Terms: GO:0000105, GO:0003879

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0947

Tuberculist Genomic Region

MMP0282 Phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI)

Details for MMP0282 - Phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI)

GO Terms: GO:0006189, GO:0009320, GO:0004638

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0282

Tuberculist Genomic Region

MMP1018 (R)-citramalate synthase (NCBI)

Details for MMP1018 - (R)-citramalate synthase (NCBI)

GO Terms: GO:0019752, GO:0046912

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1018

Tuberculist Genomic Region

MMP0308 conserved hypothetical archaeal protein (NCBI)

Details for MMP0308 - conserved hypothetical archaeal protein (NCBI)

GO Terms: GO:0008033, GO:0005737, GO:0005515, GO:0016783

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0308

Tuberculist Genomic Region

MMP1266 Glutamyl-tRNA(Gln) amidotransferase subunit D (NCBI)

Details for MMP1266 - Glutamyl-tRNA(Gln) amidotransferase subunit D (NCBI)

GO Terms: GO:0006520, GO:0006450, GO:0050567, GO:0004067

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1266

Tuberculist Genomic Region

MMP0318 Dihydroxy-acid dehydratase (NCBI)

Details for MMP0318 - Dihydroxy-acid dehydratase (NCBI)

GO Terms: GO:0009082, GO:0004160

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0318

Tuberculist Genomic Region

MMP1315 2-oxoglutarate oxidoreductase gamma subunit (NCBI)

Details for MMP1315 - 2-oxoglutarate oxidoreductase gamma subunit (NCBI)

GO Terms: GO:0006118, GO:0047553

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1315

Tuberculist Genomic Region

MMP0326 Methionyl-tRNA synthetase (NCBI)

Details for MMP0326 - Methionyl-tRNA synthetase (NCBI)

GO Terms: GO:0006431, GO:0005737, GO:0000049, GO:0004825, GO:0004869, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0326

Tuberculist Genomic Region

MMP1352 NAD binding site:TonB-dependent receptor protein:Thiamine biosynthesis Thi4 protein (NCBI)

Details for MMP1352 - NAD binding site:TonB-dependent receptor protein:Thiamine biosynthesis Thi4 protein (NCBI)

GO Terms: GO:0006118, GO:0009228, GO:0016491

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1352

Tuberculist Genomic Region

MMP0345 Conserved hypothetical protein (NCBI)

Details for MMP0345 - Conserved hypothetical protein (NCBI)

GO Terms: GO:0006810

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0345

Tuberculist Genomic Region

MMP1470 Prefoldin alpha subunit (GimC alpha subunit). (NCBI)

Details for MMP1470 - Prefoldin alpha subunit (GimC alpha subunit). (NCBI)

GO Terms: GO:0006457, GO:0016272, GO:0051082

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1470

Tuberculist Genomic Region

MMP0346 2-hydroxyglutaryl-CoA dehydratase (Component D) related protein (NCBI)

Details for MMP0346 - 2-hydroxyglutaryl-CoA dehydratase (Component D) related protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0346

Tuberculist Genomic Region

MMP1587 conserved hypothetical archaeal protein (NCBI)

Details for MMP1587 - conserved hypothetical archaeal protein (NCBI)

GO Terms: GO:0016020, GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1587

Tuberculist Genomic Region

MMP0359 Glycosyl transferase, family 2 (NCBI)

Details for MMP0359 - Glycosyl transferase, family 2 (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0359

Tuberculist Genomic Region

MMP1588 D-3-phosphoglycerate dehydrogenase (NCBI)

Details for MMP1588 - D-3-phosphoglycerate dehydrogenase (NCBI)

GO Terms: GO:0006564, GO:0016597, GO:0004617, GO:0051287

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1588

Tuberculist Genomic Region

MMP0408 H+-transporting two-sector ATPase, A subunit (NCBI)

Details for MMP0408 - H+-transporting two-sector ATPase, A subunit (NCBI)

GO Terms: GO:0015992, GO:0016469, GO:0016820

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0408

Tuberculist Genomic Region

MMP1589 Carbamoyl-phosphate synthase small chain (NCBI)

Details for MMP1589 - Carbamoyl-phosphate synthase small chain (NCBI)

GO Terms: GO:0006807, GO:0006541, GO:0009058, GO:0005524, GO:0004088

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1589

Tuberculist Genomic Region

MMP0539 3-isopropylmalate dehydrogenase (NCBI)

Details for MMP0539 - 3-isopropylmalate dehydrogenase (NCBI)

GO Terms: GO:0009098, GO:0003862, GO:0051287

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0539

Tuberculist Genomic Region

MMP1615 Conserved hypothetical protein (NCBI)

Details for MMP1615 - Conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1615

Tuberculist Genomic Region

MMP0666 Na+/Pi-cotransporter related protein (NCBI)

Details for MMP0666 - Na+/Pi-cotransporter related protein (NCBI)

GO Terms: GO:0006817, GO:0016020, GO:0015321

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0666

Tuberculist Genomic Region

MMP0541 Phosphoserine phosphatase (NCBI)

Details for MMP0541 - Phosphoserine phosphatase (NCBI)

GO Terms: GO:0006564, GO:0004647

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0541

Tuberculist Genomic Region

MMP0696 Prolyl-tRNA synthetase (NCBI)

Details for MMP0696 - Prolyl-tRNA synthetase (NCBI)

GO Terms: GO:0006433, GO:0005737, GO:0004827, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0696

Tuberculist Genomic Region

MMP1105 succinate-CoA ligase (ADP-forming), beta chain (NCBI)

Details for MMP1105 - succinate-CoA ligase (ADP-forming), beta chain (NCBI)

GO Terms: GO:0008152, GO:0009361, GO:0005524, GO:0004775

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1105

Tuberculist Genomic Region

MMP0708 conserved hypothetical protein (NCBI)

Details for MMP0708 - conserved hypothetical protein (NCBI)

GO Terms: GO:0008152, GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0708

Tuberculist Genomic Region

MMP1146 Amidophosphoribosyltransferase (NCBI)

Details for MMP1146 - Amidophosphoribosyltransferase (NCBI)

GO Terms: GO:0009113, GO:0009116, GO:0004044

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1146

Tuberculist Genomic Region

MMP0893 CTP synthase (NCBI)

Details for MMP0893 - CTP synthase (NCBI)

GO Terms: GO:0006221, GO:0003883

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0893

Tuberculist Genomic Region

MMP1316 2-oxoglutarate oxidoreductase beta subunit (NCBI)

Details for MMP1316 - 2-oxoglutarate oxidoreductase beta subunit (NCBI)

GO Terms: GO:0047553, GO:0030976

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1316

Tuberculist Genomic Region

Motif 1: e-value: 0.16 e-value: 2400
Regulator Interaction Influence Weight Other Influences

H2

up-regulates 0.30
archaeal histone A (NCBI)

H2

up-regulates 0.27
transcriptional regulator related protein (NCBI)

H2

up-regulates 0.19
LysR family member (NCBI)

H2

up-regulates 0.13
Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0009260 ribonucleotide biosynthetic process 25 1.04 4 0.0111
BP GO:0046390 ribose phosphate biosynthetic process 25 1.04 4 0.0111
BP GO:0009259 ribonucleotide metabolic process 26 1.08 4 0.0129
BP GO:0019693 ribose phosphate metabolic process 27 1.12 4 0.0148
BP GO:1901137 carbohydrate derivative biosynthetic pro... 27 1.12 4 0.0148
BP GO:0009165 nucleotide biosynthetic process 28 1.17 4 0.0170
BP GO:1901293 nucleoside phosphate biosynthetic proces... 28 1.17 4 0.0170
BP GO:0006753 nucleoside phosphate metabolic process 31 1.29 4 0.0247
BP GO:0009117 nucleotide metabolic process 31 1.29 4 0.0247
BP GO:1901135 carbohydrate derivative metabolic proces... 34 1.42 4 0.0343
BP GO:0006213 pyrimidine nucleoside metabolic process 8 0.33 2 0.0376
BP GO:0006220 pyrimidine nucleotide metabolic process 8 0.33 2 0.0376
BP GO:0006221 pyrimidine nucleotide biosynthetic proce... 8 0.33 2 0.0376
BP GO:0009218 pyrimidine ribonucleotide metabolic proc... 8 0.33 2 0.0376
BP GO:0009220 pyrimidine ribonucleotide biosynthetic p... 8 0.33 2 0.0376
BP GO:0046131 pyrimidine ribonucleoside metabolic proc... 8 0.33 2 0.0376
BP GO:0046132 pyrimidine ribonucleoside biosynthetic p... 8 0.33 2 0.0376
BP GO:0046134 pyrimidine nucleoside biosynthetic proce... 8 0.33 2 0.0376
BP GO:0034654 nucleobase-containing compound biosynthe... 35 1.46 4 0.0380
BP GO:0044711 single-organism biosynthetic process 74 3.08 6 0.0381
BP GO:0090407 organophosphate biosynthetic process 36 1.50 4 0.0419
BP GO:0044238 primary metabolic process 101 4.21 7 0.0447
BP GO:0055086 nucleobase-containing small molecule met... 37 1.54 4 0.0461
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0047553 2-oxoglutarate synthase activity 4 0.07 2 0.0015
MF GO:0016625 oxidoreductase activity, acting on the a... 7 0.12 2 0.0052
MF GO:0016491 oxidoreductase activity 78 1.31 4 0.0339
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