MSMEG_5426 MSMEG_5426 Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)]
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_5426	MSMEG_5426	glmU	glmU, MSMEG_5426, MSMEI_5277		Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)]				17295914, 18955433

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0053	0.53
msm_bicluster_0145	0.62

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0R3C7	4532260;	WP_011730527.1, YP_889665.1	ABK75163, AFP41719	IPR005882, IPR001451, IPR025877, IPR029044, IPR011004	ENOG4105CAJ, COG1207	EOG6Z6FQZ

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
Acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + N-acetyl-alpha-D-glucosamine 1-phosphate, ECO:0000255|HAMAP-Rule:MF_01631}.; UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-acetyl-alpha-D-glucosamine, ECO:0000255|HAMAP-Rule:MF_01631}.	msb:LJ00_26815, msg:MSMEI_5277, msm:MSMEG_5426	Nucleotide-sugar biosynthesis, UDP-N-acetyl-alpha-D-glucosamine biosynthesis, N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2. {ECO:0000255|HAMAP-Rule:MF_01631}., Nucleotide-sugar biosynthesis, UDP-N-acetyl-alpha-D-glucosamine biosynthesis, UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1. {ECO:0000255|HAMAP-Rule:MF_01631}., Bacterial outer membrane biogenesis, LPS lipid A biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01631}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0006048 GO:0003977 GO:0000902 GO:0071555 GO:0005737 GO:0019134 GO:0009245 GO:0009103 GO:0000287 GO:0009252 GO:0008360 -

GO:0006048

GO:0003977

GO:0000902

GO:0071555

GO:0005737

GO:0019134

GO:0009245

GO:0009103

GO:0000287

GO:0009252

GO:0008360

String Network

Link to STRINGS	STRINGS Network
MSMEG_5426

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