Module 197 Residual: 0.52Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Summary

Residual	Motif 1 e-value	Motif 2 e-value	Conditions	Genes	version
0.52	0.000000000000029	0.021	82	28	20160204

Motifs

Motif 1
	e-value: 0.000000000000029
Motif 2
	e-value: 0.021

Module Plots

Members

MSMEG_4752 Uncharacterized protein	MSMEG_6103 Dihydropteroate synthase (DHPS) (EC 2.5.1.15) (Dihydropteroate pyrophosphorylase)
MSMEG_4753 Antioxidant, AhpC/TSA family protein (EC 1.11.1.15) (Bacterioferritin comigratory protein)	MSMEG_6102 7,8-dihydroneopterin aldolase (EC 4.1.2.25)
MSMEG_2397 Transcriptional regulator, AsnC family (Transcriptional regulatory protein, AsnC family protein)	MSMEG_6104 GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I)
MSMEG_3229 Uncharacterized protein	MSMEG_6510 Transport permease protein
MSMEG_4298 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Ketopantoate hydroxymethyltransferase)	MSMEG_2880 Enoyl-CoA hydratase (Enoyl-CoA hydratase/isomerase) (EC 4.2.1.17)
MSMEG_6509 ABC-type drug export system, ATP-binding protein	MSMEG_3231 ABC transporter, CydDC cysteine exporter (CydDC-E) family protein, permease/ATP-binding protein CydD (Transmembrane ATP-binding protein ABC transporter cydD) (EC 3.6.3.25)
MSMEG_6508 MarR family transcriptional regulator (MarR-family protein transcriptional regulator)	MSMEG_3232 Cytochrome D ubiquinol oxidase, subunit II (EC 1.10.3.-) (Integral membrane cytochrome D ubiquinol oxidase (Subunit II) CydB) (EC 3.1.3.1)
MSMEG_2398 Thiamine-monophosphate kinase (TMP kinase) (Thiamine-phosphate kinase) (EC 2.7.4.16)	MSMEG_3233 Cytochrome D ubiquinol oxidase subunit 1 (EC 1.10.3.-) (Putative cytochrome ubiquinol oxidase subunit)
MSMEG_6193 Anion-transporting ATPase (EC 3.6.3.16)	MSMEG_5968 Polysaccharide biosynthesis protein
MSMEG_6195 Anion-transporting ATPase (EC 3.6.3.16) (Ion-transporting ATPase)	MSMEG_2879 Acyl-CoA dehydrogenase
MSMEG_3593 Uncharacterized protein	MSMEG_2878 Acyl-CoA dehydrogenase (Putative acyl-CoA dehydrogenase)
MSMEG_3592 Uncharacterized protein	MSMEG_6012 Putative acyl-CoA dehydrogenase
MSMEG_6101 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3)	MSMEG_4297 Diacylglycerol O-acyltransferase (EC 2.3.1.20)
MSMEG_6100 Uncharacterized protein	MSMEG_2810 Major facilitator superfamily MFS_1 (Major facilitator superfamily protein)

Conditions

Bedaquiline.vs..DMSO.30min

WT.vs..DglnR.N_starvation_rep2

WT.vs..DamtR.without.N_rep1

Biological.replicate.2.of.7..panaxydol.treatment

dcpA.knockout.rep2

Mycobacterium.smegmatis.Spheroplast.induced

Plogcy5plogcy3slide110norm

Biological.replicate.3.of.7..falcarinol.treatment

dosR.WT_Replicate3

Tet.CarD.vs.Control..Replicates.1..2..and.3.

dosR.WT_Replicate1

Stationary.cultures.induced.to.express.I.SceI.for.45.minutes..T.45...ATc.

WT.vs..DamtR.N.surplus_dyeswap_rep2

Wild.type.rep1.x

Wild.type.rep1.y

MB100pruR.vs..MB100.rep.4

Biological.replicate.6.of.6..negative.control

WT.vs..DamtR.without.N_.dyeswap_rep1

WT.vs..DamtR.without.N_.dyeswap_rep2

Biological.replicate.1.of.6..isoniazid.treatment

Biological.replicate.1.of.7..ethambutol.treatment

Biological.replicate.6.of.6..kanamycin.treatment

rel.knockout.rep2

rel.knockout.rep1

Bedaquiline.vs..DMSO..45min

MB100pruR.vs..MB100.rep.2

WT.vs..DamtR.without.N_rep2

Biological.replicate.3.of.7..ethambutol.treatment

Biological.replicate.4.of.6..kanamycin.treatment

X0.6..vs..50..air.saturation.Replicate.1

X3dbfcy5plogcy3slide601norm

X0.6..vs..50..air.saturation.Replicate.3

X0.6..vs..50..air.saturation.Replicate.2

X0.6..vs..50..air.saturation.Replicate.5

X0.6..vs..50..air.saturation.Replicate.4

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep2

M.smegmatis_mc2_155_dMSMEG_0166_study_mutant_rep1

Biological.replicate.7.of.7..panaxydol.treatment

Bedaquiline.vs..DMSO.15min

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep4

Biological.replicate.5.of.7..panaxydol.treatment

Stationary.cultures.control.without.induction.of.I.SceI.expression..T.0...Atc.

Plogcy5plogcy3slide111norm

stphcy5plogcy3slide580norm

Biological.replicate.3.of.6..kanamycin.treatment

Biological.replicate.4.of.7..ethambutol.treatment

Biological.replicate.2.of.7..ethambutol.treatment

WT_log.phase_rep1

WT.with.vs..without.N_dye.swap_rep1

X2.5..vs..50..air.saturation.Replicate.1

WT.with.vs..without.N_dye.swap_rep2

Biological.replicate.2.of.6..kanamycin.treatment

Log.phase.cultures.induced.to.express.I.SceI.for.45.minutes..T.45...ATc.

Biological.replicate.6.of.6..isoniazid.treatment

mc2155.vs.Dcrp1.replicate.3

Slow.vs..Fast.Replicate.4

Slow.vs..Fast.Replicate.5

Bedaquiline.vs..DMSO.60min

Biological.replicate.5.of.6..isoniazid.treatment

Slow.vs..Fast.Replicate.1

Slow.vs..Fast.Replicate.2

Slow.vs..Fast.Replicate.3

X4dbfcy5plogcy3slide480norm

mc2155.vs.Dcrp1.replicate.1

mc2155.pMind..vs.mc2155.pMind.6189.replicate.2

BatchCulture_LBTbroth_ExponentialPhase_Replicate4

WT.vs..DamtR.N.surplus_.dyeswap_rep1

WT.with.vs..without.N_rep2

WT.with.vs..without.N_rep1

Biological.replicate.1.of.6..negative.control

X2XR.rep2

mc2155.pMind..vs.mc2155.pMind.6189.replicate.1

WT.vs..DglnR.N_starvation_rep1

BatchCulture_LBTbroth_StationaryPhase_Replicate4

JR121..pJR29.VapC..vs..JR121..pJR230..VapBC..rep2

Plogcy5plogcy3slide113norm

BatchCulture_LBTbroth_StationaryPhase_Replicate3

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep3

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep2

M.smegmatis_mc2_155_dMSMEG_0166_study_wild.type_rep1

Biological.replicate.5.of.6..kanamycin.treatment

WT.vs..DamtR.N.surplus_rep2

Comments