MSMEG_4298 MSMEG_4298 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Ketopantoate hydroxymethyltransferase)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_4298	MSMEG_4298	panB	panB, MSMEG_4298, MSMEI_4197		3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Ketopantoate hydroxymethyltransferase)				17295914, 18955433

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0054	0.58
msm_bicluster_0197	0.52

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0R087	4535698;	WP_011729713.1, YP_888575.1	ABK69960, AFP40654, AIU09389	IPR003700, IPR015813	COG0413, ENOG4105CCG	EOG63C0WN

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H(2)O = tetrahydrofolate + 2-dehydropantoate, ECO:0000256|HAMAP-Rule:MF_00156, ECO:0000256|SAAS:SAAS00387818}.	msb:LJ00_21305, msg:MSMEI_4197, msm:MSMEG_4298	Cofactor biosynthesis, (R)-pantothenate biosynthesis, (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2. {ECO:0000256|HAMAP-Rule:MF_00156, ECO:0000256|SAAS:SAAS00387859}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0003864 GO:0005737 GO:0046872 GO:0008168 GO:0015940 -

GO:0003864

GO:0005737

GO:0046872

GO:0008168

GO:0015940

String Network

Link to STRINGS	STRINGS Network
MSMEG_4298

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