MSMEG_5104 MSMEG_5104 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) (Tetrahydrodipicolinate N-succinyltransferase) (THDP succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_5104	MSMEG_5104	dapD	dapD, MSMEG_5104, MSMEI_4976		2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) (Tetrahydrodipicolinate N-succinyltransferase) (THDP succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)				17295914, 18955433

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0158	0.60
msm_bicluster_0544	0.51

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0R2G5	4531456;	WP_011730317.1, YP_889353.1	ABK71765, AFP41420	IPR019875, IPR001451, IPR011004, IPR026586	ENOG4105EJ3, COG2171	EOG6HQSR3

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H(2)O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate, ECO:0000255|HAMAP-Rule:MF_02122}.	msb:LJ00_25235, msg:MSMEI_4976, msm:MSMEG_5104	Amino-acid biosynthesis, L-lysine biosynthesis via DAP pathway, LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 1/3. {ECO:0000255|HAMAP-Rule:MF_02122}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0008666 GO:0005737 GO:0019877 GO:0009089 GO:0000287 -

GO:0008666

GO:0005737

GO:0019877

GO:0009089

GO:0000287

String Network

Link to STRINGS	STRINGS Network
MSMEG_5104

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