pfam13949

Submitted by Anonymous (not verified) on Thu, 02/12/2015 - 13:45
CD Accession: 
pfam13949
CD Definition: 
ALIX V-shaped domain binding to HIV; The binding of the LYPxL motif of late HIV p6Gag and EIAV p9Gag to this domain is necessary for viral budding.This domain is generally central between an N-terminal Bro1 domain, pfam03097 and a C-terminal proline-rich domain. The retroviruses thus used this domain to hijack the ESCRT system of the cell.
CD Name: 
ALIX_LYPXL_bnd
CD Superfamily: 
-