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- ubiquitin ligase complex
- protein polyubiquitination
- p53 binding
- chromatin binding
- transcription coactivator activity
- ubiquitin-protein ligase activity
- protein binding
- nucleus
- nucleolus
- regulation of transcription, DNA-templated
- ubiquitin-dependent protein catabolic process
- zinc ion binding
- histone monoubiquitination
- chromatin modification
- histone ubiquitination
- ligase activity
- negative regulation of cell migration
- positive regulation of histone methylation
- ubiquitin protein ligase binding
- HULC complex
- histone H2B ubiquitination
- histone binding
- positive regulation of transcription, DNA-templated
- metal ion binding
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