Adam17 a disintegrin and metallopeptidase domain 17 (11491)

Symbol Product Feature Type Strand Chr
11491 Adam17 a disintegrin and metallopeptidase domain 17 protein-coding 12
Synonyms
CD156b | Tace
GO ID Category Definition Evidence
  • response to hypoxia
  • positive regulation of protein phosphorylation
  • germinal center formation
  • metalloendopeptidase activity
  • Notch binding
  • interleukin-6 receptor binding
  • integrin binding
  • protein binding
  • extracellular region
  • cytoplasm
  • plasma membrane
  • integral component of plasma membrane
  • cell-cell junction
  • focal adhesion
  • proteolysis
  • membrane protein ectodomain proteolysis
  • cell adhesion
  • epidermal growth factor receptor signaling pathway
  • Notch signaling pathway
  • Notch receptor processing
  • integrin-mediated signaling pathway
  • peptidase activity
  • metallopeptidase activity
  • zinc ion binding
  • positive regulation of cell proliferation
  • cell surface
  • positive regulation of T cell chemotaxis
  • actin cytoskeleton
  • membrane
  • integral component of membrane
  • apical plasma membrane
  • hydrolase activity
  • SH3 domain binding
  • PDZ domain binding
  • B cell differentiation
  • positive regulation of cell growth
  • positive regulation of cell migration
  • positive regulation of transforming growth factor beta receptor signaling pathway
  • positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
  • response to lipopolysaccharide
  • ruffle membrane
  • negative regulation of interleukin-8 production
  • positive regulation of chemokine production
  • regulation of mast cell apoptotic process
  • T cell differentiation in thymus
  • cell adhesion mediated by integrin
  • epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
  • response to drug
  • negative regulation of apoptotic process
  • membrane raft
  • positive regulation of epidermal growth factor-activated receptor activity
  • metal ion binding
  • spleen development
  • cell motility
  • PMA-inducible membrane protein ectodomain proteolysis
  • positive regulation of cellular component movement
  • response to high density lipoprotein particle
Motif 1 Motif 2 Residual
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Entrez ID STRINGS Network
STRING
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