Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (117149) | Macrophage Network Portal

Summary

	Symbol	Product	Feature Type	Strand	Chr
117149	Tirap	toll-interleukin 1 receptor (TIR) domain-containing adaptor protein	protein-coding		9

Synonyms

Synonyms
AA407980 \| C130027E04Rik \| Mal \| Tlr4ap \| Wyatt

DB XRef

Ensembl	MGI	VEGA
ENSMUSG00000032041	MGI:2152213	OTTMUSG00000042147

GO Terms

GO ID	Category	Definition	Evidence
GO:0002376 GO:0005080 GO:0005515 GO:0005546 GO:0005622 GO:0005737 GO:0005777 GO:0005886 GO:0006954 GO:0007165 GO:0007166 GO:0007249 GO:0007257 GO:0009617 GO:0016020 GO:0030099 GO:0030139 GO:0030890 GO:0032496 GO:0032587 GO:0032648 GO:0032658 GO:0032735 GO:0032738 GO:0032757 GO:0032760 GO:0034137 GO:0034141 GO:0034145 GO:0034146 GO:0035662 GO:0035663 GO:0035665 GO:0042803 GO:0043123 GO:0044130 GO:0045087 GO:0045088 GO:0045089 GO:0045410 GO:0046330 GO:0046982 GO:0050830 GO:0051092 GO:0070374 GO:0070498 GO:0070935 GO:0071221 GO:0071223 GO:0090023 GO:0090073 GO:2000340 GO:2000343	Process Function Component	immune system process protein kinase C binding protein binding phosphatidylinositol-4,5-bisphosphate binding intracellular cytoplasm peroxisome plasma membrane inflammatory response signal transduction cell surface receptor signaling pathway I-kappaB kinase/NF-kappaB signaling activation of JUN kinase activity response to bacterium membrane myeloid cell differentiation endocytic vesicle positive regulation of B cell proliferation response to lipopolysaccharide ruffle membrane regulation of interferon-beta production regulation of interleukin-15 production positive regulation of interleukin-12 production positive regulation of interleukin-15 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of toll-like receptor 2 signaling pathway positive regulation of toll-like receptor 3 signaling pathway positive regulation of toll-like receptor 4 signaling pathway toll-like receptor 5 signaling pathway Toll-like receptor 4 binding Toll-like receptor 2 binding TIRAP-dependent toll-like receptor 4 signaling pathway protein homodimerization activity positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of growth of symbiont in host innate immune response regulation of innate immune response positive regulation of innate immune response positive regulation of interleukin-6 biosynthetic process positive regulation of JNK cascade protein heterodimerization activity defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity positive regulation of ERK1 and ERK2 cascade interleukin-1-mediated signaling pathway 3'-UTR-mediated mRNA stabilization cellular response to bacterial lipopeptide cellular response to lipoteichoic acid positive regulation of neutrophil chemotaxis positive regulation of protein homodimerization activity positive regulation of chemokine (C-X-C motif) ligand 1 production positive regulation of chemokine (C-X-C motif) ligand 2 production	IEA ISO IPI IDA IMP NAS

Regulatory Modules

	Motif 1	Motif 2	Residual

Regulation

Displaying 1 - 1 of 1

Regulator Locus	Interaction	Weight

String Network

Entrez ID	STRINGS Network
STRING

Add comment

Log in or register to post comments