Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (117149)

Symbol Product Feature Type Strand Chr
117149 Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein protein-coding 9
Synonyms
AA407980 | C130027E04Rik | Mal | Tlr4ap | Wyatt
GO ID Category Definition Evidence
  • immune system process
  • protein kinase C binding
  • protein binding
  • phosphatidylinositol-4,5-bisphosphate binding
  • intracellular
  • cytoplasm
  • peroxisome
  • plasma membrane
  • inflammatory response
  • signal transduction
  • cell surface receptor signaling pathway
  • I-kappaB kinase/NF-kappaB signaling
  • activation of JUN kinase activity
  • response to bacterium
  • membrane
  • myeloid cell differentiation
  • endocytic vesicle
  • positive regulation of B cell proliferation
  • response to lipopolysaccharide
  • ruffle membrane
  • regulation of interferon-beta production
  • regulation of interleukin-15 production
  • positive regulation of interleukin-12 production
  • positive regulation of interleukin-15 production
  • positive regulation of interleukin-8 production
  • positive regulation of tumor necrosis factor production
  • positive regulation of toll-like receptor 2 signaling pathway
  • positive regulation of toll-like receptor 3 signaling pathway
  • positive regulation of toll-like receptor 4 signaling pathway
  • toll-like receptor 5 signaling pathway
  • Toll-like receptor 4 binding
  • Toll-like receptor 2 binding
  • TIRAP-dependent toll-like receptor 4 signaling pathway
  • protein homodimerization activity
  • positive regulation of I-kappaB kinase/NF-kappaB signaling
  • negative regulation of growth of symbiont in host
  • innate immune response
  • regulation of innate immune response
  • positive regulation of innate immune response
  • positive regulation of interleukin-6 biosynthetic process
  • positive regulation of JNK cascade
  • protein heterodimerization activity
  • defense response to Gram-positive bacterium
  • positive regulation of NF-kappaB transcription factor activity
  • positive regulation of ERK1 and ERK2 cascade
  • interleukin-1-mediated signaling pathway
  • 3'-UTR-mediated mRNA stabilization
  • cellular response to bacterial lipopeptide
  • cellular response to lipoteichoic acid
  • positive regulation of neutrophil chemotaxis
  • positive regulation of protein homodimerization activity
  • positive regulation of chemokine (C-X-C motif) ligand 1 production
  • positive regulation of chemokine (C-X-C motif) ligand 2 production
Motif 1 Motif 2 Residual
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Entrez ID STRINGS Network
STRING
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