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- nucleus
- mitochondrion
- mitochondrial outer membrane
- cytosol
- apoptotic process
- extrinsic apoptotic signaling pathway via death domain receptors
- intrinsic apoptotic signaling pathway in response to DNA damage
- membrane
- integral component of membrane
- protein homodimerization activity
- regulation of apoptotic process
- positive regulation of apoptotic process
- negative regulation of apoptotic process
- protein heterodimerization activity
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
- negative regulation of intrinsic apoptotic signaling pathway
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