Ptk2 PTK2 protein tyrosine kinase 2 (14083)

Symbol Product Feature Type Strand Chr
14083 Ptk2 PTK2 protein tyrosine kinase 2 protein-coding 15
Synonyms
FAK | FRNK | Fadk | mKIAA4203 | p125FAK
GO ID Category Definition Evidence
  • MAPK cascade
  • nucleotide binding
  • microtubule cytoskeleton organization
  • angiogenesis
  • blood vessel development
  • vasculogenesis
  • neuron migration
  • positive regulation of protein phosphorylation
  • actin binding
  • protein kinase activity
  • protein tyrosine kinase activity
  • non-membrane spanning protein tyrosine kinase activity
  • signal transducer activity
  • integrin binding
  • protein binding
  • ATP binding
  • nucleus
  • nucleolus
  • cytoplasm
  • cytosol
  • cytoskeleton
  • plasma membrane
  • focal adhesion
  • protein phosphorylation
  • cellular component movement
  • signal complex assembly
  • integrin-mediated signaling pathway
  • JNK cascade
  • multicellular organismal development
  • positive regulation of cell proliferation
  • regulation of cell shape
  • JUN kinase binding
  • positive regulation of phosphatidylinositol 3-kinase signaling
  • intercalated disc
  • positive regulation of smooth muscle cell migration
  • membrane
  • kinase activity
  • phosphorylation
  • basolateral plasma membrane
  • apical plasma membrane
  • nuclear body
  • transferase activity
  • transferase activity, transferring phosphorus-containing groups
  • peptidyl-tyrosine phosphorylation
  • protein kinase binding
  • central nervous system neuron axonogenesis
  • negative regulation of cell-cell adhesion
  • lamellipodium
  • cell junction
  • extracellular matrix organization
  • positive regulation of cell growth
  • positive regulation of cell migration
  • negative regulation of cell migration
  • cellular chloride ion homeostasis
  • protein complex binding
  • regulation of cell adhesion mediated by integrin
  • establishment of nucleus localization
  • regulation of cell proliferation
  • SH2 domain binding
  • sarcolemma
  • negative regulation of apoptotic process
  • endothelial cell migration
  • phosphatidylinositol 3-kinase binding
  • regulation of osteoblast differentiation
  • positive regulation of cell adhesion
  • positive regulation of protein kinase activity
  • positive regulation of vasodilation
  • negative regulation of organ growth
  • protein autophosphorylation
  • ephrin receptor signaling pathway
  • positive regulation of smooth muscle cell proliferation
  • positive regulation of phagocytosis
  • negative regulation of axonogenesis
  • positive regulation of synaptic transmission
  • positive regulation of protein kinase B signaling
  • negative regulation of synapse assembly
  • positive regulation of glial cell proliferation
  • growth hormone receptor signaling pathway
  • positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
  • negative regulation of anoikis
Motif 1 Motif 2 Residual
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Entrez ID STRINGS Network
STRING
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