Irak1 interleukin-1 receptor-associated kinase 1 (16179)

Symbol Product Feature Type Strand Chr
16179 Irak1 interleukin-1 receptor-associated kinase 1 protein-coding X
Synonyms
AA408924 | IRAK | IRAK-1 | IRAK1-S | Il1rak | Plpk | mPLK
GO ID Category Definition Evidence
  • nucleotide binding
  • regulation of cytokine-mediated signaling pathway
  • immune system process
  • protein kinase activity
  • protein serine/threonine kinase activity
  • interleukin-1 receptor binding
  • protein binding
  • ATP binding
  • intracellular
  • nucleus
  • cytoplasm
  • lipid particle
  • protein phosphorylation
  • signal transduction
  • activation of NF-kappaB-inducing kinase activity
  • JNK cascade
  • membrane
  • kinase activity
  • phosphorylation
  • transferase activity
  • transferase activity, transferring phosphorus-containing groups
  • cytokine-mediated signaling pathway
  • heat shock protein binding
  • lipopolysaccharide-mediated signaling pathway
  • negative regulation of NF-kappaB transcription factor activity
  • response to peptidoglycan
  • response to lipopolysaccharide
  • toll-like receptor 2 signaling pathway
  • toll-like receptor 4 signaling pathway
  • cellular response to heat
  • protein homodimerization activity
  • positive regulation of MAP kinase activity
  • positive regulation of JUN kinase activity
  • innate immune response
  • negative regulation of transcription, DNA-templated
  • protein autophosphorylation
  • protein heterodimerization activity
  • positive regulation of smooth muscle cell proliferation
  • positive regulation of NF-kappaB transcription factor activity
  • protein oligomerization
  • interleukin-1-mediated signaling pathway
  • response to interleukin-1
  • negative regulation of cholesterol efflux
Motif 1 Motif 2 Residual
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Entrez ID STRINGS Network
STRING
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