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- nuclear chromatin
- RNA polymerase II core promoter proximal region sequence-specific DNA binding
- p53 binding
- transcription cofactor activity
- nucleus
- cytoplasm
- plasma membrane
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
- DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
- cell surface
- negative regulation of transcription by competitive promoter binding
- membrane
- integral component of membrane
- apical plasma membrane
- positive regulation of transcription from RNA polymerase II promoter in response to stress
- regulation of transcription from RNA polymerase II promoter in response to stress
- positive regulation of histone H4 acetylation
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
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