Pkd2 polycystic kidney disease 2 (18764)

Symbol Product Feature Type Strand Chr
18764 Pkd2 polycystic kidney disease 2 protein-coding 5
Synonyms
C030034P18Rik | PC2 | TRPP2
GO ID Category Definition Evidence
  • kidney development
  • liver development
  • embryonic placenta development
  • heart looping
  • polycystin complex
  • detection of nodal flow
  • receptor binding
  • voltage-gated ion channel activity
  • voltage-gated calcium channel activity
  • voltage-gated sodium channel activity
  • calcium channel activity
  • potassium channel activity
  • calcium ion binding
  • protein binding
  • cytoplasm
  • endoplasmic reticulum
  • endoplasmic reticulum membrane
  • plasma membrane
  • integral component of plasma membrane
  • cell-cell junction
  • cilium
  • transport
  • ion transport
  • calcium ion transport
  • cellular calcium ion homeostasis
  • cell cycle arrest
  • positive regulation of cytosolic calcium ion concentration
  • JAK-STAT cascade
  • determination of left/right symmetry
  • heart development
  • cytoskeletal protein binding
  • basal plasma membrane
  • positive regulation of gene expression
  • channel activity
  • membrane
  • integral component of membrane
  • voltage-gated cation channel activity
  • lamellipodium
  • regulation of cAMP metabolic process
  • motile primary cilium
  • nonmotile primary cilium
  • positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
  • positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
  • filamentous actin
  • sodium ion transmembrane transport
  • ciliary basal body
  • regulation of cell proliferation
  • identical protein binding
  • protein homodimerization activity
  • actinin binding
  • cytoplasmic sequestering of transcription factor
  • cell projection
  • HLH domain binding
  • ion channel binding
  • basal cortex
  • positive regulation of nitric oxide biosynthetic process
  • positive regulation of transcription from RNA polymerase II promoter
  • metal ion binding
  • calcium-induced calcium release activity
  • detection of mechanical stimulus
  • ATPase binding
  • release of sequestered calcium ion into cytosol
  • muscle alpha-actinin binding
  • alpha-actinin binding
  • transmembrane transport
  • negative regulation of ryanodine-sensitive calcium-release channel activity
  • placenta blood vessel development
  • renal tubule morphogenesis
  • calcium ion transmembrane transport
  • positive regulation of cell cycle arrest
  • integral component of cytoplasmic side of endoplasmic reticulum membrane
  • cellular response to hydrostatic pressure
  • cellular response to osmotic stress
  • cellular response to fluid shear stress
  • integral component of lumenal side of endoplasmic reticulum membrane
  • potassium ion transmembrane transport
  • determination of liver left/right asymmetry
  • renal system development
  • mitotic spindle
  • regulation of calcium ion import
  • negative regulation of G1/S transition of mitotic cell cycle
Motif 1 Motif 2 Residual
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Entrez ID STRINGS Network
STRING
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