Psen1 presenilin 1 (19164)

Symbol Product Feature Type Strand Chr
19164 Psen1 presenilin 1 protein-coding 12
Synonyms
Ad3h | PS-1 | PS1 | S182
GO ID Category Definition Evidence
  • autophagic vacuole assembly
  • negative regulation of transcription from RNA polymerase II promoter
  • activation of MAPKK activity
  • kinetochore
  • blood vessel development
  • cell fate specification
  • somitogenesis
  • neuron migration
  • positive regulation of receptor recycling
  • negative regulation of protein phosphorylation
  • positive regulation of protein phosphorylation
  • heart looping
  • hematopoietic progenitor cell differentiation
  • T cell activation involved in immune response
  • myeloid leukocyte differentiation
  • endopeptidase activity
  • aspartic-type endopeptidase activity
  • calcium channel activity
  • protein binding
  • intracellular
  • cell
  • nucleus
  • nuclear outer membrane
  • mitochondrion
  • mitochondrial inner membrane
  • lysosomal membrane
  • endoplasmic reticulum
  • smooth endoplasmic reticulum
  • rough endoplasmic reticulum
  • Golgi apparatus
  • centrosome
  • plasma membrane
  • integral component of plasma membrane
  • cell cortex
  • negative regulation of protein kinase activity
  • protein glycosylation
  • proteolysis
  • membrane protein ectodomain proteolysis
  • calcium ion transport
  • mitochondrial transport
  • cellular calcium ion homeostasis
  • autophagy
  • apoptotic process
  • cellular response to DNA damage stimulus
  • response to oxidative stress
  • cell adhesion
  • negative regulation of epidermal growth factor-activated receptor activity
  • regulation of epidermal growth factor-activated receptor activity
  • Notch signaling pathway
  • Notch receptor processing
  • brain development
  • heart development
  • learning or memory
  • memory
  • beta-catenin binding
  • peptidase activity
  • embryo development
  • post-embryonic development
  • cell surface
  • protein transport
  • L-glutamate transport
  • choline transport
  • membrane
  • integral component of membrane
  • synaptic vesicle targeting
  • apical plasma membrane
  • cell-cell adhesion
  • protein processing
  • hydrolase activity
  • cerebral cortex cell migration
  • Cajal-Retzius cell differentiation
  • dorsal/ventral neural tube patterning
  • cerebral cortex development
  • neurogenesis
  • Z disc
  • PDZ domain binding
  • neuron differentiation
  • embryonic limb morphogenesis
  • axon
  • dendrite
  • growth cone
  • forebrain development
  • cytoplasmic vesicle
  • neuromuscular junction
  • nuclear membrane
  • positive regulation of proteasomal ubiquitin-dependent protein catabolic process
  • endoplasmic reticulum calcium ion homeostasis
  • beta-amyloid formation
  • ciliary rootlet
  • segmentation
  • intracellular signal transduction
  • locomotion
  • regulation of phosphorylation
  • anagen
  • amyloid precursor protein catabolic process
  • neuron projection
  • neuronal cell body
  • positive regulation of apoptotic process
  • negative regulation of apoptotic process
  • positive regulation of catalytic activity
  • dendritic shaft
  • membrane-bounded organelle
  • protein complex
  • regulation of protein binding
  • positive regulation of MAP kinase activity
  • negative regulation of neuron apoptotic process
  • skin morphogenesis
  • cellular protein metabolic process
  • membrane raft
  • cadherin binding
  • positive regulation of protein kinase activity
  • regulation of synaptic plasticity
  • perinuclear region of cytoplasm
  • thymus development
  • neuron development
  • skeletal system morphogenesis
  • brain morphogenesis
  • beta-amyloid metabolic process
  • epithelial cell proliferation
  • negative regulation of axonogenesis
  • positive regulation of coagulation
  • T cell receptor signaling pathway
  • neuron apoptotic process
  • negative regulation of ubiquitin-protein ligase activity
  • smooth endoplasmic reticulum calcium ion homeostasis
  • protein maturation
  • regulation of synaptic transmission, glutamatergic
  • regulation of resting membrane potential
  • calcium ion transmembrane transport
  • gamma-secretase complex
  • negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
  • negative regulation of apoptotic signaling pathway
Motif 1 Motif 2 Residual
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Entrez ID STRINGS Network
STRING
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