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- negative regulation of transcription from RNA polymerase II promoter
- protein polyubiquitination
- ossification
- neural tube closure
- positive regulation of T cell cytokine production
- ubiquitin-protein ligase activity
- signal transducer activity
- protein binding
- intracellular
- nucleus
- cytoplasm
- lipid particle
- cytosol
- plasma membrane
- protein complex assembly
- immune response
- signal transduction
- I-kappaB kinase/NF-kappaB signaling
- activation of NF-kappaB-inducing kinase activity
- JNK cascade
- zinc ion binding
- organ morphogenesis
- cytoplasmic side of plasma membrane
- protein ubiquitination
- ligase activity
- cytokine-mediated signaling pathway
- antigen processing and presentation of exogenous peptide antigen via MHC class II
- protein kinase binding
- osteoclast differentiation
- mitogen-activated protein kinase kinase kinase binding
- ubiquitin protein ligase binding
- positive regulation of lipopolysaccharide-mediated signaling pathway
- nuclear membrane
- thioesterase binding
- activation of protein kinase activity
- positive regulation of interleukin-2 production
- CD40 receptor complex
- T-helper 1 type immune response
- positive regulation of T cell proliferation
- odontogenesis of dentin-containing tooth
- histone deacetylase binding
- regulation of apoptotic process
- myeloid dendritic cell differentiation
- positive regulation of I-kappaB kinase/NF-kappaB signaling
- protein complex
- protein kinase B binding
- positive regulation of JUN kinase activity
- positive regulation of interleukin-12 biosynthetic process
- positive regulation of interleukin-6 biosynthetic process
- bone resorption
- positive regulation of osteoclast differentiation
- negative regulation of transcription, DNA-templated
- positive regulation of transcription from RNA polymerase II promoter
- bone remodeling
- metal ion binding
- protein N-terminus binding
- cell development
- perinuclear region of cytoplasm
- positive regulation of smooth muscle cell proliferation
- T cell receptor signaling pathway
- regulation of immunoglobulin secretion
- positive regulation of sequence-specific DNA binding transcription factor activity
- positive regulation of NF-kappaB transcription factor activity
- protein autoubiquitination
- interleukin-1-mediated signaling pathway
- protein K63-linked ubiquitination
- response to interleukin-1
- positive regulation of transcription regulatory region DNA binding
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