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- protein polyubiquitination
- DNA binding
- double-stranded DNA binding
- ubiquitin-protein ligase activity
- protein kinase C binding
- protein binding
- transcription, DNA-templated
- zinc ion binding
- ligase activity
- negative regulation of NF-kappaB transcription factor activity
- positive regulation of NF-kappaB import into nucleus
- positive regulation of apoptotic process
- positive regulation of I-kappaB kinase/NF-kappaB signaling
- ubiquitin binding
- proteasome-mediated ubiquitin-dependent protein catabolic process
- positive regulation of transcription from RNA polymerase II promoter
- metal ion binding
- T cell receptor signaling pathway
- positive regulation of NF-kappaB transcription factor activity
- negative regulation of necroptotic process
- LUBAC complex
- protein linear polyubiquitination
- positive regulation of extrinsic apoptotic signaling pathway
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