Map2k1 mitogen-activated protein kinase kinase 1 (26395) | Macrophage Network Portal

Summary

	Symbol	Product	Feature Type	Strand	Chr
26395	Map2k1	mitogen-activated protein kinase kinase 1	protein-coding		9

Synonyms

Synonyms
MAPKK1 \| MEKK1 \| Mek1 \| Prkmk1

DB XRef

Ensembl	MGI	VEGA
ENSMUSG00000004936	MGI:1346866	OTTMUSG00000016895

GO Terms

GO ID	Category	Definition	Evidence
GO:0000165 GO:0000166 GO:0000187 GO:0003056 GO:0004672 GO:0004674 GO:0004708 GO:0004712 GO:0004713 GO:0004728 GO:0005524 GO:0005634 GO:0005737 GO:0005739 GO:0005769 GO:0005770 GO:0005794 GO:0005829 GO:0005856 GO:0005874 GO:0005886 GO:0005925 GO:0005938 GO:0006468 GO:0006979 GO:0007050 GO:0007067 GO:0008283 GO:0008285 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0017016 GO:0019901 GO:0023014 GO:0030182 GO:0030216 GO:0030335 GO:0030424 GO:0030425 GO:0031435 GO:0032320 GO:0032402 GO:0032839 GO:0032872 GO:0032968 GO:0034111 GO:0035335 GO:0043204 GO:0043539 GO:0045597 GO:0046579 GO:0047496 GO:0048313 GO:0048471 GO:0048678 GO:0048812 GO:0048870 GO:0051291 GO:0051384 GO:0060674 GO:0060711 GO:0071902 GO:0090170 GO:0090398 GO:2000641	Process Function Component	MAPK cascade nucleotide binding activation of MAPK activity regulation of vascular smooth muscle contraction protein kinase activity protein serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity receptor signaling protein tyrosine phosphatase activity ATP binding nucleus cytoplasm mitochondrion early endosome late endosome Golgi apparatus cytosol cytoskeleton microtubule plasma membrane focal adhesion cell cortex protein phosphorylation response to oxidative stress cell cycle arrest mitosis cell proliferation negative regulation of cell proliferation kinase activity phosphorylation transferase activity transferase activity, transferring phosphorus-containing groups Ras GTPase binding protein kinase binding signal transduction by phosphorylation neuron differentiation keratinocyte differentiation positive regulation of cell migration axon dendrite mitogen-activated protein kinase kinase kinase binding positive regulation of Ras GTPase activity melanosome transport dendrite cytoplasm regulation of stress-activated MAPK cascade positive regulation of transcription elongation from RNA polymerase II promoter negative regulation of homotypic cell-cell adhesion peptidyl-tyrosine dephosphorylation perikaryon protein serine/threonine kinase activator activity positive regulation of cell differentiation positive regulation of Ras protein signal transduction vesicle transport along microtubule Golgi inheritance perinuclear region of cytoplasm response to axon injury neuron projection morphogenesis cell motility protein heterooligomerization response to glucocorticoid placenta blood vessel development labyrinthine layer development positive regulation of protein serine/threonine kinase activity regulation of Golgi inheritance cellular senescence regulation of early endosome to late endosome transport	IMP ISO IEA TAS IDA

Regulatory Modules

	Motif 1	Motif 2	Residual

Regulation

Displaying 1 - 1 of 1

Regulator Locus	Interaction	Weight

String Network

Entrez ID	STRINGS Network
STRING

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