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- MAPK cascade
- nucleotide binding
- activation of MAPKK activity
- activation of MAPK activity
- magnesium ion binding
- positive regulation of protein phosphorylation
- immune system process
- protein kinase activity
- protein serine/threonine kinase activity
- MAP kinase kinase kinase activity
- protein binding
- ATP binding
- intracellular
- cytoplasm
- endoplasmic reticulum
- protein phosphorylation
- apoptotic process
- activation of cysteine-type endopeptidase activity involved in apoptotic process
- response to stress
- JNK cascade
- intrinsic apoptotic signaling pathway in response to oxidative stress
- cysteine-type endopeptidase activator activity involved in apoptotic process
- regulation of cell death
- kinase activity
- phosphorylation
- transferase activity
- transferase activity, transferring phosphorus-containing groups
- protein kinase binding
- protein phosphatase binding
- protein homodimerization activity
- positive regulation of apoptotic process
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
- innate immune response
- metal ion binding
- cellular response to hydrogen peroxide
- programmed necrotic cell death
- cellular response to reactive nitrogen species
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