|  |  | DNA damage checkpointtelomere maintenancechromosome, telomeric regionnuclear chromosome, telomeric regionin utero embryonic developmentblastocyst growthdamaged DNA bindingATP-dependent DNA helicase activityintracellularnucleusreplication forkchromosomenucleolusDNA repairdouble-strand break repaircellular response to DNA damage stimuluscell cyclemitotic cell cycle checkpointmitotic G2 DNA damage checkpointmeiosistranscription factor bindingcell proliferationpositive regulation of cell proliferationPML bodyMre11 complexpositive regulation of protein autophosphorylationDNA duplex unwindingpositive regulation of kinase activitysite of double-strand breaknuclear inclusion bodyisotype switchingnegative regulation of neuron differentiationprotein N-terminus bindingregulation of fibroblast proliferationneuromuscular process controlling balanceintrinsic apoptotic signaling pathway
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