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- MAPK cascade
- nucleotide binding
- activation of MAPKK activity
- protein kinase activity
- protein serine/threonine kinase activity
- NF-kappaB-inducing kinase activity
- MAP kinase kinase kinase activity
- protein binding
- ATP binding
- intracellular
- nucleus
- cytoplasm
- protein phosphorylation
- response to stress
- immune response
- I-kappaB kinase/NF-kappaB signaling
- kinase activity
- phosphorylation
- transferase activity
- transferase activity, transferring phosphorus-containing groups
- signal transduction by phosphorylation
- NIK/NF-kappaB signaling
- positive regulation of I-kappaB kinase/NF-kappaB signaling
- intracellular membrane-bounded organelle
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