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- ubiquitin ligase complex
- phosphotyrosine binding
- ubiquitin-protein ligase activity
- signal transducer activity
- epidermal growth factor receptor binding
- calcium ion binding
- nucleus
- ubiquitin-dependent protein catabolic process
- cell surface receptor signaling pathway
- negative regulation of epidermal growth factor-activated receptor activity
- zinc ion binding
- protein ubiquitination
- SH3 domain binding
- regulation of signaling
- negative regulation of epidermal growth factor receptor signaling pathway
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process
- negative regulation of MAP kinase activity
- metal ion binding
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