PITA_111 megaCluster: 10 Residual: 0.23

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
PITA_111 10 0.23 9 0 0.673529 0.872

Members

Displaying 1 - 48 of 48
108037 serine hydroxymethyltransferase 2 (mitochondrial)

Details for - - serine hydroxymethyltransferase 2 (mitochondrial)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 108037

Tuberculist Genomic Region

117198 influenza virus NS1A binding protein

Details for - - influenza virus NS1A binding protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 117198

Tuberculist Genomic Region

14360 Fyn proto-oncogene

Details for - - Fyn proto-oncogene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14360

Tuberculist Genomic Region

14886 general transcription factor II I

Details for - - general transcription factor II I

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14886

Tuberculist Genomic Region

15216 hemochromatosis

Details for RP23-480B19.9 - hemochromatosis

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15216

Tuberculist Genomic Region

17345 antigen identified by monoclonal antibody Ki 67

Details for - - antigen identified by monoclonal antibody Ki 67

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17345

Tuberculist Genomic Region

192654 phospholipase A2, group XV

Details for - - phospholipase A2, group XV

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 192654

Tuberculist Genomic Region

207818 small cell adhesion glycoprotein

Details for - - small cell adhesion glycoprotein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 207818

Tuberculist Genomic Region

217340 ring finger protein 157

Details for RP23-184G6.4 - ring finger protein 157

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 217340

Tuberculist Genomic Region

228482 Rho GTPase activating protein 11A

Details for RP23-288M21.5 - Rho GTPase activating protein 11A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 228482

Tuberculist Genomic Region

29869 unc-51 like kinase 2

Details for RP23-278F12.5 - unc-51 like kinase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 29869

Tuberculist Genomic Region

319504 neuron-glia-CAM-related cell adhesion molecule

Details for - - neuron-glia-CAM-related cell adhesion molecule

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 319504

Tuberculist Genomic Region

330812 ring finger protein 150

Details for - - ring finger protein 150

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 330812

Tuberculist Genomic Region

60455 transmembrane protein 8 (five membrane-spanning domains)

Details for - - transmembrane protein 8 (five membrane-spanning domains)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 60455

Tuberculist Genomic Region

637515 NLR family, pyrin domain containing 1B

Details for DN-72H10.1 - NLR family, pyrin domain containing 1B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 637515

Tuberculist Genomic Region

68137 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

Details for - - KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68137

Tuberculist Genomic Region

70974 phosphoglucomutase 2-like 1

Details for - - phosphoglucomutase 2-like 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70974

Tuberculist Genomic Region

72117 N(alpha)-acetyltransferase 50, NatE catalytic subunit

Details for - - N(alpha)-acetyltransferase 50, NatE catalytic subunit

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72117

Tuberculist Genomic Region

74149 zinc finger protein 946

Details for - - zinc finger protein 946

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74149

Tuberculist Genomic Region

94275 melanoma antigen, family D, 1

Details for RP23-272D10.5 - melanoma antigen, family D, 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 94275

Tuberculist Genomic Region

102141 sorting nexin 25

Details for - - sorting nexin 25

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 102141

Tuberculist Genomic Region

104923 acireductone dioxygenase 1

Details for - - acireductone dioxygenase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 104923

Tuberculist Genomic Region

105171 arrestin domain containing 3

Details for - - arrestin domain containing 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 105171

Tuberculist Genomic Region

107476 acetyl-Coenzyme A carboxylase alpha

Details for RP23-123O10.1 - acetyl-Coenzyme A carboxylase alpha

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 107476

Tuberculist Genomic Region

108012 adaptor-related protein complex 1, sigma 2 subunit

Details for RP23-391L6.1 - adaptor-related protein complex 1, sigma 2 subunit

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 108012

Tuberculist Genomic Region

108961 E2F transcription factor 8

Details for - - E2F transcription factor 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 108961

Tuberculist Genomic Region

114128 lysosomal-associated protein transmembrane 4B

Details for - - lysosomal-associated protein transmembrane 4B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 114128

Tuberculist Genomic Region

11856 Rho GTPase activating protein 6

Details for RP23-24O15.2 - Rho GTPase activating protein 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11856

Tuberculist Genomic Region

12628 complement component factor h

Details for - - complement component factor h

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12628

Tuberculist Genomic Region

13204 DEAH (Asp-Glu-Ala-His) box polypeptide 15

Details for - - DEAH (Asp-Glu-Ala-His) box polypeptide 15

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13204

Tuberculist Genomic Region

17001 leukotriene C4 synthase

Details for RP23-319B15.7 - leukotriene C4 synthase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17001

Tuberculist Genomic Region

19128 protein S (alpha)

Details for - - protein S (alpha)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19128

Tuberculist Genomic Region

19684 radixin

Details for - - radixin

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19684

Tuberculist Genomic Region

20336 exocyst complex component 4

Details for - - exocyst complex component 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20336

Tuberculist Genomic Region

268930 protein kinase, membrane associated tyrosine/threonine 1

Details for - - protein kinase, membrane associated tyrosine/threonine 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 268930

Tuberculist Genomic Region

320209 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11

Details for - - DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 320209

Tuberculist Genomic Region

382406 POC1 centriolar protein homolog B (Chlamydomonas)

Details for - - POC1 centriolar protein homolog B (Chlamydomonas)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 382406

Tuberculist Genomic Region

56421 phosphofructokinase, platelet

Details for - - phosphofructokinase, platelet

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56421

Tuberculist Genomic Region

59013 heterogeneous nuclear ribonucleoprotein H1

Details for RP23-121P11.1 - heterogeneous nuclear ribonucleoprotein H1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 59013

Tuberculist Genomic Region

619883 predicted gene 6109

Details for - - predicted gene 6109

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 619883

Tuberculist Genomic Region

66200 COMM domain containing 6

Details for - - COMM domain containing 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66200

Tuberculist Genomic Region

67705 RIKEN cDNA 1810058I24 gene

Details for - - RIKEN cDNA 1810058I24 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67705

Tuberculist Genomic Region

68743 anillin, actin binding protein

Details for - - anillin, actin binding protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68743

Tuberculist Genomic Region

68801 ELOVL family member 5, elongation of long chain fatty acids (yeast)

Details for - - ELOVL family member 5, elongation of long chain fatty acids (yeast)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68801

Tuberculist Genomic Region

75292 protein kinase D3

Details for - - protein kinase D3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 75292

Tuberculist Genomic Region

12567 cyclin-dependent kinase 4

Details for - - cyclin-dependent kinase 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12567

Tuberculist Genomic Region

65964 sterile alpha motif and leucine zipper containing kinase AZK

Details for RP23-146F24.1 - sterile alpha motif and leucine zipper containing kinase AZK

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 65964

Tuberculist Genomic Region

13860 epidermal growth factor receptor pathway substrate 8

Details for - - epidermal growth factor receptor pathway substrate 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13860

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
E2F1_MA0024.1 0.217391 0.000000552

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.0000000000013 AAAAMNAAAAAA NA 9.7 TTAACATTNNT NA

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.08 GACGCG NA 1.04 GCGCTNCG NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.45 ACGACG NA NA 0.59 TANGACGT NA NA

3p UTR PITA

miRNAs percTargets pValue
mmu-miR-543 0.692308 0.0000592

3p UTR TargetScan

miRNAs percTargets pValue
NA

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