PITA_145 megaCluster: 8 Residual: 0.17

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
PITA_145 8 0.17 15 0 0.952228 0

Members

Displaying 1 - 30 of 30
12626 centrin 3

Details for - - centrin 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12626

Tuberculist Genomic Region

13595 phenylalkylamine Ca2+ antagonist (emopamil) binding protein

Details for RP23-27I6.10-001 - phenylalkylamine Ca2+ antagonist (emopamil) binding protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13595

Tuberculist Genomic Region

227095 3-hydroxyisobutyryl-Coenzyme A hydrolase

Details for - - 3-hydroxyisobutyryl-Coenzyme A hydrolase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 227095

Tuberculist Genomic Region

237336 TATA box binding protein-like 1

Details for - - TATA box binding protein-like 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 237336

Tuberculist Genomic Region

24060 solute carrier family 35 (CMP-sialic acid transporter), member 1

Details for RP23-76M15.2 - solute carrier family 35 (CMP-sialic acid transporter), member 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 24060

Tuberculist Genomic Region

245828 trafficking protein particle complex 1

Details for RP23-26L6.10-004 - trafficking protein particle complex 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 245828

Tuberculist Genomic Region

53893 nudix (nucleoside diphosphate linked moiety X)-type motif 5

Details for RP23-307E15.2 - nudix (nucleoside diphosphate linked moiety X)-type motif 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 53893

Tuberculist Genomic Region

66671 cyclin H

Details for - - cyclin H

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66671

Tuberculist Genomic Region

67005 polymerase (RNA) III (DNA directed) polypeptide K

Details for RP23-322G1.6 - polymerase (RNA) III (DNA directed) polypeptide K

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67005

Tuberculist Genomic Region

70544 transmembrane protein 242

Details for - - transmembrane protein 242

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70544

Tuberculist Genomic Region

74164 nuclear transcription factor, X-box binding 1

Details for RP23-28I8.5 - nuclear transcription factor, X-box binding 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74164

Tuberculist Genomic Region

78586 S1 RNA binding domain 1

Details for - - S1 RNA binding domain 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 78586

Tuberculist Genomic Region

12802 cannabinoid receptor 2 (macrophage)

Details for RP23-161N17.5 - cannabinoid receptor 2 (macrophage)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12802

Tuberculist Genomic Region

17449 malate dehydrogenase 1, NAD (soluble)

Details for RP23-198N8.1 - malate dehydrogenase 1, NAD (soluble)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17449

Tuberculist Genomic Region

20751 sepiapterin reductase

Details for - - sepiapterin reductase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20751

Tuberculist Genomic Region

22247 uridine monophosphate synthetase

Details for - - uridine monophosphate synthetase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22247

Tuberculist Genomic Region

233987 zinc finger protein 958

Details for - - zinc finger protein 958

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 233987

Tuberculist Genomic Region

30841 lysine (K)-specific demethylase 2B

Details for - - lysine (K)-specific demethylase 2B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 30841

Tuberculist Genomic Region

320727 importin 8

Details for RP24-441E15.3 - importin 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 320727

Tuberculist Genomic Region

51798 enoyl coenzyme A hydratase 1, peroxisomal

Details for - - enoyl coenzyme A hydratase 1, peroxisomal

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 51798

Tuberculist Genomic Region

57373 A kinase (PRKA) interacting protein 1

Details for - - A kinase (PRKA) interacting protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 57373

Tuberculist Genomic Region

66622 ubiquitin protein ligase E3 component n-recognin 7 (putative)

Details for - - ubiquitin protein ligase E3 component n-recognin 7 (putative)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66622

Tuberculist Genomic Region

70152 methyltransferase like 7A1

Details for - - methyltransferase like 7A1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70152

Tuberculist Genomic Region

71710 leucine rich repeat and coiled-coil domain containing 1

Details for - - leucine rich repeat and coiled-coil domain containing 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71710

Tuberculist Genomic Region

72050 KDEL (Lys-Asp-Glu-Leu) containing 1

Details for - - KDEL (Lys-Asp-Glu-Leu) containing 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72050

Tuberculist Genomic Region

73451 zinc finger protein 763

Details for - - zinc finger protein 763

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 73451

Tuberculist Genomic Region

74552 NIPA-like domain containing 3

Details for RP23-332E2.5 - NIPA-like domain containing 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74552

Tuberculist Genomic Region

75597 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2

Details for - - NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 75597

Tuberculist Genomic Region

11545 poly (ADP-ribose) polymerase family, member 1

Details for - - poly (ADP-ribose) polymerase family, member 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11545

Tuberculist Genomic Region

16970 lymphoid-restricted membrane protein

Details for RP24-216M19.3 - lymphoid-restricted membrane protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16970

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
V_IPF1_Q4_M00436 0.2 0.000000896

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.0000000036 AAAMAAARCMA NA 0.1 AAAGYWNAAMA IRF1_MA0050.1

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.11 CGGAAG SPI1_MA0080.1, GABPA_MA0062.1, GABPA_MA0062.2, ELK4_MA0076.1, ELK1_MA0028.1, SPI1_MA0080.2, V$GABP_B_M00341, V$GADP_01_M01258, V$GABPA_Q4_M01660, V$NRF2_01_M00108, V$ELK1_04_M01165, V$ELK1_03_M01163, V$ELK1_06_M02059, V$EHF_06_M02745, V$GABPBETA_Q3_M01876, V$ELK1_02_M00025, V$ETV3_02_M02068, V$ER81_02_M02065, V$SAP1A_01_M01167, V$ERG_03_M02062, V$CETS1_Q6_M01870, V$ERG_01_M01752, V$FLI1_01_M02038, V$ESE1_Q3_M01214, V$ESE1_02_M02055, V$ELF4_01_M01979, V$ERF_01_M01984, V$CETS168_Q6_M00743, V$ERM_01_M01992, V$TEL1_01_M01993, V$EHF_03_M02052, V$ETV3_01_M01990, V$TEL1_02_M02070, V$SPI1_04_M02278, V$ELF1_Q5_M01266, V$PEA3_01_M01991, V$PEA3_02_M02066, V$ERG_02_M01985, V$FLI1_02_M02073, V$EHF_02_M01974, V$CETS2_01_M01989, V$STAT1_02_M00492, V$NERF_01_M01976, V$NET_02_M02060, V$ELF5_03_M02057, V$SAP1A_03_M02058, V$CETS1_02_M02063, V$ELF2_02_M02054, V$CETS1_01_M01986, V$FLI1_Q6_M01208, V$ERM_02_M02069, V$PET1_01_M02037, V$ESE1_01_M01977, V$SPIC_02_M02077, V$ETV7_01_M02071, V$SPI1_Q5_M02031, V$PU1_Q6_M00658, V$ER71_02_M02067, V$GABPA_01_M02039, V$ELF4_02_M02056, V$EHF_07_M02849, V$ELK1_01_M00007, V$SPIC_01_M02042, V$SPIB_02_M02041, V$ER71_01_M01988, V$ER81_01_M01987, V$ELF1_01_M01975, V$STAT3_02_M00497, V$ERF_02_M02061, V$ETS_Q6_M00971, V$SPIB_01_M01204, V$ELK1_05_M01981, V$ELF5_02_M01980, V$CETS1P54_01_M00032, V$SPIB_03_M02076, V$SAP1A_02_M01983, V$NET_01_M01982, V$SPI1_03_M02078, V$ELF_02_M02053, V$PEA3_Q6_M00655, V$TEL2_Q6_M00678, V$PET1_02_M02072, V$ETS2_Q6_M01207, V$SPI1_01_M01203, V$CETS2_02_M02064, Spic.1, Elf4.1, Elf2.1, Ehf.2, Elk3.1, Elf5.1, Etv1.1, Elk1.1, Gabpa.3, Sfpi1.3, Etv6.1, Gm5454.1, Ehf.3, Elf3.3, Erg.1, Etv5.1, Ets1.1, Fli1.1, Ehf.1, Elk4.1, Etv3.1, Elf3.2, Gm4881.1, Etv4.1, ETV6_ETS_full_monomeric_10_1, ELF1_ETS_full_monomeric_12_1, EHF_ETS_full_monomeric_12_1, ELF3_ETS_DBD_monomeric_12_1, ELK1_ETS_full_monomeric_10_1, ELF3_ETS_full_monomeric_13_1, Elk3_ETS_DBD_monomeric_10_1, ELF4_ETS_full_monomeric_12_1, ETV6_ETS_full_dimeric_15_1, SPI1_ETS_full_monomeric_14_1, ELK1_ETS_full_dimeric_17_1, ERF_ETS_DBD_monomeric_10_1, ETS1_ETS_full_dimeric_18_1, ETV3_ETS_DBD_monomeric_10_1, SPIB_ETS_DBD_monomeric_14_1, GABPA_ETS_full_monomeric_10_1, ELF5_ETS_full_monomeric_11_1, ELK4_ETS_DBD_monomeric_10_1, ERG_ETS_full_monomeric_10_1, ETV1_ETS_DBD_monomeric_10_1, SPIC_ETS_full_monomeric_14_1, FEV_ETS_DBD_monomeric_10_1, FLI1_ETS_full_monomeric_10_1, ETV4_ETS_DBD_monomeric_10_1 1.18 CGCTTGCG NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.57 TCGCCG NA NA 0.6 AGTTCNNT NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-466m-3p 0.413793 0.0000415

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