PITA_15 megaCluster: 2 Residual: 0.26

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_15	2	0.26	14	0	0.837779	0

Members

Displaying 1 - 44 of 44

TFBS DB TF

TFs	percTargets	pValue
IRF1_MA0050.1	0.342857	0.00000306

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000095	ARWAAAAAAAAA	NA	8.3	CMNCCCCGCCCC	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$SP1_Q6_01_M00931, V$KLF7_03_M02773, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$SP1_02_M01303, V$SP1_Q4_01_M00932, V$GC_01_M00255, V$GKLF_02_M01588, V$SP1_Q6_M00196, V$CKROX_Q2_M01175, V$CACD_01_M01113, V$MAZ_Q6_01_M02023, V$SP1_03_M02281, V$SP1_01_M00008, V$MAZ_Q6_M00649, V$ZFP281_01_M01597, V$ZFP281_04_M02831, V$EKLF_Q5_M01874, V$KROX_Q6_M00982, V$MAZR_01_M00491, V$SP4_03_M02810, V$ZFP740_03_M02834, V$UF1H3BETA_Q6_M01068, V$ZBP89_Q4_M01816, V$EGR1_Q6_M01873, V$SMAD4_04_M02898, V$BCL6B_04_M02844, V$E2F3_Q6_M02089, V$ZFP410_04_M02936, V$WT1_Q6_01_M02036, V$ZNF219_01_M01122, V$EGR1_06_M02744, V$CACCCBINDINGFACTOR_Q6_M00721, V$ASCL2_04_M02841, V$SP1SP3_Q4_M01219, V$FKLF_Q5_M01837, V$KLF15_Q2_M01714, Klf7.1, Zfp281.2, Sp4.1, Zfp740.1, Bcl6b.2, Smad3.1, Egr1.1, Zfp410.1, Ascl2.2, Zif268.1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP8_C2H2_DBD_monomeric_12_1, KLF14_C2H2_DBD_monomeric_14_1, ZNF740_C2H2_full_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1, KLF13_C2H2_full_monomeric_18_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.17	CGCCCA	Egr1_MA0162.1, V$EGR1_02_M01972, V$EGR1_01_M00243, V$EGR1_Q6_M01873, V$KLF7_04_M02877, V$SP1_Q6_01_M00931, V$SP1_Q4_01_M00932, V$KROX_Q6_M00982, V$NGFIC_01_M00244, V$EGR3_01_M00245, V$EGR1_06_M02744, V$SP1_Q2_01_M00933, V$EGR2_01_M00246, V$KLF7_03_M02773, Zif268.1, Klf7.2, Egr1.1, Klf7.1, EGR2_C2H2_DBD_monomeric_11_1, EGR2_C2H2_full_monomeric_15_1, SP8_C2H2_DBD_monomeric_12_1, Egr3_C2H2_DBD_monomeric_15_1, EGR1_C2H2_full_monomeric_14_1, EGR4_C2H2_DBD_monomeric_16_2	1.02	CAGCGCTG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.48	CGATAC	NA	NA	0.56	ACCGNGGC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

100503907 predicted gene, 19955 Details for - - predicted gene, 19955 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503907 Tuberculist Genomic Region	100504215 predicted gene, 20115 Details for - - predicted gene, 20115 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504215 Tuberculist Genomic Region
100504452 predicted gene, 20235 Details for - - predicted gene, 20235 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504452 Tuberculist Genomic Region	100504699 RIKEN cDNA 9030425P06 gene Details for - - RIKEN cDNA 9030425P06 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504699 Tuberculist Genomic Region
12140 fatty acid binding protein 7, brain Details for - - fatty acid binding protein 7, brain GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12140 Tuberculist Genomic Region	13051 chemokine (C-X3-C motif) receptor 1 Details for - - chemokine (C-X3-C motif) receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13051 Tuberculist Genomic Region
13654 early growth response 2 Details for - - early growth response 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13654 Tuberculist Genomic Region	13807 enolase 2, gamma neuronal Details for - - enolase 2, gamma neuronal GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13807 Tuberculist Genomic Region
17113 mannose-6-phosphate receptor, cation dependent Details for - - mannose-6-phosphate receptor, cation dependent GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17113 Tuberculist Genomic Region	18173 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 Details for - - solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18173 Tuberculist Genomic Region
19734 regulator of G-protein signaling 16 Details for - - regulator of G-protein signaling 16 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19734 Tuberculist Genomic Region	20529 solute carrier family 31, member 1 Details for RP24-145P21.1 - solute carrier family 31, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20529 Tuberculist Genomic Region
234135 Wolf-Hirschhorn syndrome candidate 1-like 1 (human) Details for - - Wolf-Hirschhorn syndrome candidate 1-like 1 (human) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234135 Tuberculist Genomic Region	241075 pleckstrin homology domain containing, family M, member 3 Details for - - pleckstrin homology domain containing, family M, member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241075 Tuberculist Genomic Region
243910 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 243910 Tuberculist Genomic Region	244864 layilin Details for - - layilin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 244864 Tuberculist Genomic Region
545205 olfactory receptor 111 Details for - - olfactory receptor 111 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 545205 Tuberculist Genomic Region	54616 exostoses (multiple)-like 3 Details for - - exostoses (multiple)-like 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54616 Tuberculist Genomic Region
666907 membrane-spanning 4-domains, subfamily A, member 4A Details for - - membrane-spanning 4-domains, subfamily A, member 4A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 666907 Tuberculist Genomic Region	667712 predicted gene 8777 Details for - - predicted gene 8777 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 667712 Tuberculist Genomic Region
67399 PDZ and LIM domain 7 Details for RP23-211O9.2 - PDZ and LIM domain 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67399 Tuberculist Genomic Region	71704 Rho guanine nucleotide exchange factor (GEF) 3 Details for - - Rho guanine nucleotide exchange factor (GEF) 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71704 Tuberculist Genomic Region
71712 DNA-damage regulated autophagy modulator 1 Details for - - DNA-damage regulated autophagy modulator 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71712 Tuberculist Genomic Region	72925 membrane-associated ring finger (C3HC4) 1 Details for - - membrane-associated ring finger (C3HC4) 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72925 Tuberculist Genomic Region
74704 RIKEN cDNA 4930518I15 gene Details for - - RIKEN cDNA 4930518I15 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74704 Tuberculist Genomic Region	74769 phosphatidylinositol 3-kinase, catalytic, beta polypeptide Details for - - phosphatidylinositol 3-kinase, catalytic, beta polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74769 Tuberculist Genomic Region
107607 nucleotide-binding oligomerization domain containing 1 Details for - - nucleotide-binding oligomerization domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107607 Tuberculist Genomic Region	11541 adenosine A2b receptor Details for RP23-330N10.1 - adenosine A2b receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11541 Tuberculist Genomic Region
12983 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) Details for - - colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12983 Tuberculist Genomic Region	12984 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) Details for - - colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12984 Tuberculist Genomic Region
13163 Fas death domain-associated protein Details for - - Fas death domain-associated protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13163 Tuberculist Genomic Region	16164 interleukin 13 receptor, alpha 1 Details for RP23-132G2.1 - interleukin 13 receptor, alpha 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16164 Tuberculist Genomic Region
16169 interleukin 15 receptor, alpha chain Details for RP23-114B13.4 - interleukin 15 receptor, alpha chain GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16169 Tuberculist Genomic Region	207683 immunoglobulin superfamily, member 11 Details for RP23-131M7.1 - immunoglobulin superfamily, member 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 207683 Tuberculist Genomic Region
22782 solute carrier family 30 (zinc transporter), member 1 Details for - - solute carrier family 30 (zinc transporter), member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22782 Tuberculist Genomic Region	230779 serine incorporator 2 Details for RP23-12J1.7 - serine incorporator 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230779 Tuberculist Genomic Region
234311 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 Details for - - DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234311 Tuberculist Genomic Region	381287 RIKEN cDNA A530032D15Rik gene Details for - - RIKEN cDNA A530032D15Rik gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381287 Tuberculist Genomic Region
387173 microRNA 155 Details for - - microRNA 155 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 387173 Tuberculist Genomic Region	54199 chemokine (C-C motif) receptor-like 2 Details for - - chemokine (C-C motif) receptor-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54199 Tuberculist Genomic Region
56066 chemokine (C-X-C motif) ligand 11 Details for - - chemokine (C-X-C motif) ligand 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56066 Tuberculist Genomic Region	66674 SPRY domain containing 7 Details for RP23-38F20.1 - SPRY domain containing 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66674 Tuberculist Genomic Region
667373 predicted gene 14446 Details for - - predicted gene 14446 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 667373 Tuberculist Genomic Region	668139 predicted gene 8995 Details for - - predicted gene 8995 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 668139 Tuberculist Genomic Region

Summary

Members

Details for - - predicted gene, 19955

Details for - - predicted gene, 20115

Details for - - predicted gene, 20235

Details for - - RIKEN cDNA 9030425P06 gene

Details for - - fatty acid binding protein 7, brain

Details for - - chemokine (C-X3-C motif) receptor 1

Details for - - early growth response 2

Details for - - enolase 2, gamma neuronal

Details for - - mannose-6-phosphate receptor, cation dependent

Details for - - solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

Details for - - regulator of G-protein signaling 16

Details for RP24-145P21.1 - solute carrier family 31, member 1

Details for - - Wolf-Hirschhorn syndrome candidate 1-like 1 (human)

Details for - - pleckstrin homology domain containing, family M, member 3

Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta

Details for - - layilin

Details for - - olfactory receptor 111

Details for - - exostoses (multiple)-like 3

Details for - - membrane-spanning 4-domains, subfamily A, member 4A

Details for - - predicted gene 8777

Details for RP23-211O9.2 - PDZ and LIM domain 7

Details for - - Rho guanine nucleotide exchange factor (GEF) 3

Details for - - DNA-damage regulated autophagy modulator 1

Details for - - membrane-associated ring finger (C3HC4) 1

Details for - - RIKEN cDNA 4930518I15 gene

Details for - - phosphatidylinositol 3-kinase, catalytic, beta polypeptide

Details for - - nucleotide-binding oligomerization domain containing 1

Details for RP23-330N10.1 - adenosine A2b receptor

Details for - - colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)

Details for - - colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)

Details for - - Fas death domain-associated protein

Details for RP23-132G2.1 - interleukin 13 receptor, alpha 1

Details for RP23-114B13.4 - interleukin 15 receptor, alpha chain

Details for RP23-131M7.1 - immunoglobulin superfamily, member 11

Details for - - solute carrier family 30 (zinc transporter), member 1

Details for RP23-12J1.7 - serine incorporator 2

Details for - - DEAD (Asp-Glu-Ala-Asp) box polypeptide 60

Details for - - RIKEN cDNA A530032D15Rik gene

Details for - - microRNA 155

Details for - - chemokine (C-C motif) receptor-like 2

Details for - - chemokine (C-X-C motif) ligand 11

Details for RP23-38F20.1 - SPRY domain containing 7

Details for - - predicted gene 14446

Details for - - predicted gene 8995

GO Terms

3p UTR PITA