PITA_164 megaCluster: 9 Residual: 0.19

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_164	9	0.19	15	0	0.932761	0

Members

Displaying 1 - 41 of 41

TFBS DB TF

TFs	percTargets	pValue
V_GABPBETA_Q3_M01876	0.525	0.00000334

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000000000059	TTTTTNTTTTT	NA	0.6	GGCCCCGCCCMY	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$GC_01_M00255, V$SP4_Q5_M01273, V$SP1_Q6_01_M00931, V$SP1_Q2_01_M00933, V$KLF7_03_M02773, V$SP1_03_M02281, V$MAZR_01_M00491, V$SP2_01_M01783, V$GKLF_02_M01588, V$SP1_02_M01303, V$SP4_03_M02810, V$SMAD4_04_M02898, V$UF1H3BETA_Q6_M01068, V$E2F3_Q6_M02089, V$SP1_01_M00008, V$ZFP281_01_M01597, V$SP1SP3_Q4_M01219, V$ZBP89_Q4_M01816, V$KROX_Q6_M00982, V$MAZ_Q6_01_M02023, V$CKROX_Q2_M01175, V$ZFP740_03_M02834, V$SP4_04_M02914, V$EGR1_06_M02744, V$EGR1_Q6_M01873, V$ZNF219_01_M01122, V$ZFP281_04_M02831, V$ETF_Q6_M00695, V$EGR_Q6_M00807, V$CACD_01_M01113, V$BTEB3_Q5_M01865, V$BCL6B_04_M02844, V$MAZ_Q6_M00649, Klf7.1, Sp4.1, Smad3.1, Zfp740.1, Egr1.1, Sp4.2, Zfp281.2, Zif268.1, Bcl6b.2, Zfp410.1, Klf7.2, Plagl1.1, Ascl2.2, SP4_C2H2_full_monomeric_17_1, SP1_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, KLF16_C2H2_DBD_monomeric_11_1, Klf12_C2H2_DBD_monomeric_15_1, KLF13_C2H2_full_monomeric_18_1, ZNF740_C2H2_full_monomeric_10_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, Zfp740_C2H2_DBD_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.11	CGCCCA	Egr1_MA0162.1, Zif268.1, Klf7.2, Egr1.1, Klf7.1, Sp4.1, Egr3_C2H2_DBD_monomeric_15_1, EGR2_C2H2_DBD_monomeric_11_1, EGR1_C2H2_full_monomeric_14_1, EGR2_C2H2_full_monomeric_15_1, SP8_C2H2_DBD_monomeric_12_1, EGR4_C2H2_DBD_monomeric_16_2	1.2	CGCGGCNC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.65	CGCNCTGG	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-125b-5p, mmu-miR-125a-5p, mmu-miR-351	0.6875	0.00000292

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-1962	0.411765	0.0000138

106068 solute carrier family 45, member 4 Details for - - solute carrier family 45, member 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106068 Tuberculist Genomic Region	11781 adaptor-related protein complex AP-4, mu 1 Details for - - adaptor-related protein complex AP-4, mu 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11781 Tuberculist Genomic Region
17826 family with sequence similarity 89, member B Details for - - family with sequence similarity 89, member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17826 Tuberculist Genomic Region	219144 ADP-ribosylation factor-like 11 Details for - - ADP-ribosylation factor-like 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 219144 Tuberculist Genomic Region
22368 transient receptor potential cation channel, subfamily V, member 2 Details for RP23-234K24.7 - transient receptor potential cation channel, subfamily V, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22368 Tuberculist Genomic Region	22700 zinc finger protein 40 Details for RP24-440M15.1 - zinc finger protein 40 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22700 Tuberculist Genomic Region
228607 mitochondrial antiviral signaling protein Details for RP23-387C21.3 - mitochondrial antiviral signaling protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228607 Tuberculist Genomic Region	228875 solute carrier family 35, member C2 Details for RP23-41B20.3 - solute carrier family 35, member C2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228875 Tuberculist Genomic Region
229521 synaptotagmin XI Details for - - synaptotagmin XI GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229521 Tuberculist Genomic Region	66073 thioredoxin domain containing 12 (endoplasmic reticulum) Details for RP23-31C9.2 - thioredoxin domain containing 12 (endoplasmic reticulum) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66073 Tuberculist Genomic Region
66682 trafficking protein particle complex 5 Details for - - trafficking protein particle complex 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66682 Tuberculist Genomic Region	68188 symplekin Details for - - symplekin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68188 Tuberculist Genomic Region
68731 ribosome binding factor A Details for - - ribosome binding factor A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68731 Tuberculist Genomic Region	69091 vacuolar protein sorting 26 homolog B (yeast) Details for - - vacuolar protein sorting 26 homolog B (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69091 Tuberculist Genomic Region
69769 tumor necrosis factor, alpha-induced protein 8-like 2 Details for - - tumor necrosis factor, alpha-induced protein 8-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69769 Tuberculist Genomic Region	70719 histocompatibility (minor) HA-1 Details for - - histocompatibility (minor) HA-1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70719 Tuberculist Genomic Region
71904 progestin and adipoQ receptor family member VII Details for - - progestin and adipoQ receptor family member VII GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71904 Tuberculist Genomic Region	791088 RIKEN cDNA C630016N16 gene Details for - - RIKEN cDNA C630016N16 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 791088 Tuberculist Genomic Region
102193 zinc finger, DHHC domain containing 7 Details for - - zinc finger, DHHC domain containing 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 102193 Tuberculist Genomic Region	18479 p21 protein (Cdc42/Rac)-activated kinase 1 Details for - - p21 protein (Cdc42/Rac)-activated kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18479 Tuberculist Genomic Region
20111 ribosomal protein S6 kinase polypeptide 1 Details for RP23-256C7.2 - ribosomal protein S6 kinase polypeptide 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20111 Tuberculist Genomic Region	210029 meteorin, glial cell differentiation regulator-like Details for RP23-274J5.3 - meteorin, glial cell differentiation regulator-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 210029 Tuberculist Genomic Region
21841 cytotoxic granule-associated RNA binding protein 1 Details for - - cytotoxic granule-associated RNA binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21841 Tuberculist Genomic Region	223753 ceramide kinase Details for - - ceramide kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 223753 Tuberculist Genomic Region
223921 achalasia, adrenocortical insufficiency, alacrimia Details for - - achalasia, adrenocortical insufficiency, alacrimia GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 223921 Tuberculist Genomic Region	228880 zinc finger, MYND-type containing 8 Details for RP23-108D12.1 - zinc finger, MYND-type containing 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228880 Tuberculist Genomic Region
230101 glucosidase beta 2 Details for RP23-191F22.2 - glucosidase beta 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230101 Tuberculist Genomic Region	246229 basic, immunoglobulin-like variable motif containing Details for - - basic, immunoglobulin-like variable motif containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 246229 Tuberculist Genomic Region
26416 mitogen-activated protein kinase 14 Details for RP24-137E7.1 - mitogen-activated protein kinase 14 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26416 Tuberculist Genomic Region	269587 erythrocyte protein band 4.1 Details for RP23-13A13.5 - erythrocyte protein band 4.1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269587 Tuberculist Genomic Region
272347 zinc finger protein 398 Details for - - zinc finger protein 398 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 272347 Tuberculist Genomic Region	408022 primase and polymerase (DNA-directed) Details for - - primase and polymerase (DNA-directed) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 408022 Tuberculist Genomic Region
50798 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Details for RP23-209M8.6 - glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 50798 Tuberculist Genomic Region	66950 transmembrane protein 206 Details for - - transmembrane protein 206 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66950 Tuberculist Genomic Region
68281 RIKEN cDNA 4930430F08 gene Details for - - RIKEN cDNA 4930430F08 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68281 Tuberculist Genomic Region	68366 transmembrane protein 129 Details for - - transmembrane protein 129 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68366 Tuberculist Genomic Region
68428 STEAP family member 3 Details for - - STEAP family member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68428 Tuberculist Genomic Region	72194 F-box and leucine-rich repeat protein 20 Details for RP23-309H19.11-002 - F-box and leucine-rich repeat protein 20 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72194 Tuberculist Genomic Region
72852 metallo-beta-lactamase domain containing 2 Details for - - metallo-beta-lactamase domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72852 Tuberculist Genomic Region	73338 inositol 1,4,5-triphosphate receptor interacting protein-like 1 Details for RP23-26A12.4 - inositol 1,4,5-triphosphate receptor interacting protein-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73338 Tuberculist Genomic Region
226744 consortin, connexin sorting protein Details for - - consortin, connexin sorting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226744 Tuberculist Genomic Region

Summary

Members

Details for - - solute carrier family 45, member 4

Details for - - adaptor-related protein complex AP-4, mu 1

Details for - - family with sequence similarity 89, member B

Details for - - ADP-ribosylation factor-like 11

Details for RP23-234K24.7 - transient receptor potential cation channel, subfamily V, member 2

Details for RP24-440M15.1 - zinc finger protein 40

Details for RP23-387C21.3 - mitochondrial antiviral signaling protein

Details for RP23-41B20.3 - solute carrier family 35, member C2

Details for - - synaptotagmin XI

Details for RP23-31C9.2 - thioredoxin domain containing 12 (endoplasmic reticulum)

Details for - - trafficking protein particle complex 5

Details for - - symplekin

Details for - - ribosome binding factor A

Details for - - vacuolar protein sorting 26 homolog B (yeast)

Details for - - tumor necrosis factor, alpha-induced protein 8-like 2

Details for - - histocompatibility (minor) HA-1

Details for - - progestin and adipoQ receptor family member VII

Details for - - RIKEN cDNA C630016N16 gene

Details for - - zinc finger, DHHC domain containing 7

Details for - - p21 protein (Cdc42/Rac)-activated kinase 1

Details for RP23-256C7.2 - ribosomal protein S6 kinase polypeptide 1

Details for RP23-274J5.3 - meteorin, glial cell differentiation regulator-like

Details for - - cytotoxic granule-associated RNA binding protein 1

Details for - - ceramide kinase

Details for - - achalasia, adrenocortical insufficiency, alacrimia

Details for RP23-108D12.1 - zinc finger, MYND-type containing 8

Details for RP23-191F22.2 - glucosidase beta 2

Details for - - basic, immunoglobulin-like variable motif containing

Details for RP24-137E7.1 - mitogen-activated protein kinase 14

Details for RP23-13A13.5 - erythrocyte protein band 4.1

Details for - - zinc finger protein 398

Details for - - primase and polymerase (DNA-directed)

Details for RP23-209M8.6 - glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

Details for - - transmembrane protein 206

Details for - - RIKEN cDNA 4930430F08 gene

Details for - - transmembrane protein 129

Details for - - STEAP family member 3

Details for RP23-309H19.11-002 - F-box and leucine-rich repeat protein 20

Details for - - metallo-beta-lactamase domain containing 2

Details for RP23-26A12.4 - inositol 1,4,5-triphosphate receptor interacting protein-like 1

Details for - - consortin, connexin sorting protein

GO Terms

3p UTR PITA