PITA_175 megaCluster: 10 Residual: 0.26

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
PITA_175 10 0.26 15 0 0.869502 0

Members

Displaying 1 - 28 of 28
260409 CDC42 effector protein (Rho GTPase binding) 3

Details for - - CDC42 effector protein (Rho GTPase binding) 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 260409

Tuberculist Genomic Region

54636 WD repeat domain 45

Details for RP23-109E24.3 - WD repeat domain 45

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 54636

Tuberculist Genomic Region

66257 nicolin 1

Details for - - nicolin 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66257

Tuberculist Genomic Region

100503331 high mobility group nucleosomal binding domain 2 pseudogene

Details for - - high mobility group nucleosomal binding domain 2 pseudogene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100503331

Tuberculist Genomic Region

103140 glutathione S-transferase, theta 3

Details for - - glutathione S-transferase, theta 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 103140

Tuberculist Genomic Region

108907 nucleolar and spindle associated protein 1

Details for RP23-22A15.4 - nucleolar and spindle associated protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 108907

Tuberculist Genomic Region

110460 acetyl-Coenzyme A acetyltransferase 2

Details for - - acetyl-Coenzyme A acetyltransferase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 110460

Tuberculist Genomic Region

12428 cyclin A2

Details for - - cyclin A2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12428

Tuberculist Genomic Region

12846 catechol-O-methyltransferase

Details for - - catechol-O-methyltransferase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12846

Tuberculist Genomic Region

13605 ect2 oncogene

Details for - - ect2 oncogene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13605

Tuberculist Genomic Region

14360 Fyn proto-oncogene

Details for - - Fyn proto-oncogene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14360

Tuberculist Genomic Region

14697 guanine nucleotide binding protein (G protein), beta 5

Details for - - guanine nucleotide binding protein (G protein), beta 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14697

Tuberculist Genomic Region

14865 glutathione S-transferase, mu 4

Details for RP23-214E3.8 - glutathione S-transferase, mu 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14865

Tuberculist Genomic Region

16551 kinesin family member 11

Details for - - kinesin family member 11

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16551

Tuberculist Genomic Region

170718 isocitrate dehydrogenase 3 (NAD+) beta

Details for RP23-20A6.5 - isocitrate dehydrogenase 3 (NAD+) beta

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 170718

Tuberculist Genomic Region

20250 stearoyl-Coenzyme A desaturase 2

Details for - - stearoyl-Coenzyme A desaturase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20250

Tuberculist Genomic Region

225659 centrosomal protein 76

Details for - - centrosomal protein 76

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 225659

Tuberculist Genomic Region

666938 BEN domain containing 4

Details for - - BEN domain containing 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 666938

Tuberculist Genomic Region

67168 lysophosphatidic acid receptor 6

Details for - - lysophosphatidic acid receptor 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67168

Tuberculist Genomic Region

68581 transmembrane emp24-like trafficking protein 10 (yeast)

Details for - - transmembrane emp24-like trafficking protein 10 (yeast)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68581

Tuberculist Genomic Region

72503 RIKEN cDNA 2610507B11 gene

Details for RP23-185A18.9 - RIKEN cDNA 2610507B11 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72503

Tuberculist Genomic Region

73086 ribosomal protein S6 kinase, polypeptide 5

Details for - - ribosomal protein S6 kinase, polypeptide 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 73086

Tuberculist Genomic Region

76429 phospholysine phosphohistidine inorganic pyrophosphate phosphatase

Details for - - phospholysine phosphohistidine inorganic pyrophosphate phosphatase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 76429

Tuberculist Genomic Region

76464 cancer susceptibility candidate 5

Details for RP23-15I21.2 - cancer susceptibility candidate 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 76464

Tuberculist Genomic Region

98711 retinol dehydrogenase 10 (all-trans)

Details for - - retinol dehydrogenase 10 (all-trans)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 98711

Tuberculist Genomic Region

21973 topoisomerase (DNA) II alpha

Details for RP23-333D2.5 - topoisomerase (DNA) II alpha

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 21973

Tuberculist Genomic Region

12235 budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)

Details for RP23-189N15.7 - budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12235

Tuberculist Genomic Region

18817 polo-like kinase 1

Details for - - polo-like kinase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18817

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
SP3_C2H2_DBD_monomeric_11_1, V_SP4_Q5_M01273 1, 1 0

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.00047 AAANAGNAAAA NA 2000 TTWANNTAATTR Prrx2_MA0075.1, Nobox_MA0125.1, V$OG2_01_M01162, Bsx.1, Msx3.1, Pax7.1, Lbx2.1, Og2x.1, Pou2f1.1, Meox1.1, Dlx2.1, Lhx4.1, Hoxd3.1, Hoxc6.1, Alx3.1, Dbx2.1, Rhox6.1, Barx1.1, Hoxd1.1, Pax6.1, Hoxa5.1, Vax1.1, Gsh2.1, Lhx2.1, Hoxa2.1, Hoxb6.1, Hlx1.1, Pou1f1.1, Msx1.1, Nkx1-2.1, Barx2.1, Ipf1.1, En2.1, Hoxb5.1, Lhx6.1, Pou3f1.1, Hoxa7.1, Isl2.1, Hoxc5.1, Hoxc8.1, Pou3f4.1, Hoxa3.3, Isx.1, LHX2_homeodomain_DBD_dimeric_15_1, Shox2_homeodomain_DBD_monomeric_8_1, SHOX_homeodomain_DBD_monomeric_8_1, ISX_homeodomain_full_monomeric_8_1, DLX5_homeodomain_FL_monomeric_8_1, Dlx2_homeodomain_DBD_monomeric_8_1, MEOX2_homeodomain_DBD_dimeric_17_1, PRRX1_homeodomain_full_monomeric_8_1, LHX9_homeodomain_DBD_monomeric_8_1, RAXL1_homeodomain_DBD_monomeric_8_1, VSX2_homeodomain_DBD_monomeric_8_1, VSX1_homeodomain_DBD_monomeric_8_1, DLX6_homeodomain_DBD_monomeric_8_1, Dlx1_homeodomain_DBD_monomeric_8_1, LMX1A_homeodomain_DBD_monomeric_8_1, VSX1_homeodomain_DBD_monomeric_8_1, Uncx_homeodomain_DBD_monomeric_8_1, EN1_homeodomain_full_monomeric_8_1, PRRX1_homeodomain_full_dimeric_11_1, CART1_homeodomain_DBD_dimeric_13_1, DLX4_homeodomain_DBD_monomeric_8_1, DLX3_homeodomain_DBD_monomeric_8_1, Msx3_homeodomain_DBD_monomeric_8_1, ISX_homeodomain_DBD_dimeric_13_1, PRRX2_homeodomain_full_monomeric_8_1, Lhx4_homeodomain_DBD_monomeric_8_1, EMX2_homeodomain_DBD_dimeric_14_1, Uncx_homeodomain_DBD_dimeric_13_1, LMX1B_homeodomain_full_monomeric_8_1, PHOX2A_homeodomain_DBD_dimeric_11_1, MSX1_homeodomain_full_monomeric_8_1, MSX2_homeodomain_DBD_monomeric_8_1, PDX1_homeodomain_DBD_monomeric_8_1, VAX1_homeodomain_DBD_monomeric_8_1, RAX_homeodomain_DBD_monomeric_10_1, EMX1_homeodomain_DBD_dimeric_14_1, PHOX2B_homeodomain_full_dimeric_11_1, LHX2_homeodomain_DBD_monomeric_10_1, HESX1_homeodomain_DBD_monomeric_10_1, VAX2_homeodomain_DBD_monomeric_8_1, ALX3_homeodomain_full_monomeric_10_1, PROP1_homeodomain_full_dimeric_11_1, NKX6-2_homeodomain_full_monomeric_8_1, PDX1_homeodomain_DBD_dimeric_18_1, Alx1_homeodomain_DBD_monomeric_10_1, MIXL1_homeodomain_full_monomeric_10_1, LBX2_homeodomain_DBD_monomeric_10_1, DRGX_homeodomain_DBD_dimeric_13_1, EN1_homeodomain_DBD_monomeric_10_1, PAX4_PAX_full_monomeric_8_1, Arx_homeodomain_DBD_dimeric_13_1, ESX1_homeodomain_full_monomeric_10_1, DLX1_homeodomain_DBD_monomeric_10_1, GBX1_homeodomain_DBD_monomeric_10_1, Meox2_homeodomain_DBD_monomeric_8_1, MNX1_homeodomain_DBD_monomeric_10_1, ALX3_homeodomain_full_dimeric_13_1, Lhx8_homeodomain_DBD_monomeric_8_1, GBX2_homeodomain_full_monomeric_10_1, NOTO_homeodomain_DBD_monomeric_10_1, Alx1_homeodomain_DBD_dimeric_13_1, Alx4_homeodomain_DBD_dimeric_13_1, GSX1_homeodomain_DBD_monomeric_10_1, EMX2_homeodomain_DBD_monomeric_10_1, GSX2_homeodomain_DBD_monomeric_10_1, NKX6-1_homeodomain_full_monomeric_8_1, HOXA1_homeodomain_DBD_monomeric_10_1, HOXB3_homeodomain_DBD_monomeric_10_1, HOXB2_homeodomain_DBD_monomeric_10_1, MEOX2_homeodomain_DBD_monomeric_10_1, MSX1_homeodomain_DBD_dimeric_18_1, Hoxd3_homeodomain_DBD_monomeric_10_1, Msx3_homeodomain_DBD_dimeric_18_1, HOXB5_homeodomain_DBD_monomeric_10_1, EMX1_homeodomain_DBD_monomeric_10_1, BARX1_homeodomain_DBD_monomeric_8_1, EVX2_homeodomain_DBD_monomeric_10_1, EVX1_homeodomain_DBD_monomeric_10_1, BSX_homeodomain_DBD_monomeric_8_1, MEOX1_homeodomain_full_monomeric_10_1, EN2_homeodomain_full_monomeric_10_1, Hoxa2_homeodomain_DBD_monomeric_10_1, LBX2_homeodomain_DBD_dimeric_13_1, VSX1_homeodomain_full_monomeric_11_1, MSX2_homeodomain_DBD_dimeric_18_1, HOXD8_homeodomain_DBD_monomeric_10_1, DUXA_homeodomain_DBD_dimeric_13_1, LHX6_homeodomain_full_monomeric_10_1, EN1_homeodomain_full_dimeric_14_1, POU3F3_POU_DBD_monomeric_13_1, POU6F2_POU_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.34 CGCCGA NA 1.41 GCGCGNCG Zfp161.2, Zfp161.1

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.73 TTNKGACT NA NA NA NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
NA

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