PITA_228 megaCluster: 1 Residual: 0.21

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_228	1	0.21	15	0	0.917317	0

Members

Displaying 1 - 47 of 47

TFBS DB TF

TFs	percTargets	pValue
V_NFE2_01_M00037	0.348837	0.0000172

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000002	CYCCGCCCCNCC	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_Q2_01_M00933, V$SP1_Q6_01_M00931, V$SP4_Q5_M01273, V$SP1_Q4_01_M00932, V$SP1_Q6_M00196, V$GC_01_M00255, V$SP1_02_M01303, V$SP1_03_M02281, V$ZNF219_01_M01122, V$BCL6B_04_M02844, V$CKROX_Q2_M01175, V$UF1H3BETA_Q6_M01068, V$KLF7_03_M02773, V$ZFP281_01_M01597, V$ETF_Q6_M00695, V$ZFP410_04_M02936, V$GKLF_02_M01588, V$EGR1_Q6_M01873, V$KLF15_Q2_M01714, V$ZBP89_Q4_M01816, V$SP1_01_M00008, V$ZFP281_04_M02831, V$EGR1_06_M02744, V$MAZ_Q6_01_M02023, V$SP1SP3_Q4_M01219, V$WT1_Q6_01_M02036, V$KROX_Q6_M00982, V$MAZR_01_M00491, V$MAZ_Q6_M00649, V$SMAD4_04_M02898, V$GKLF_Q4_M01835, V$BTEB3_Q5_M01865, V$FKLF_Q5_M01837, V$SP2_01_M01783, V$CACD_01_M01113, V$ZFP740_03_M02834, V$SP4_03_M02810, Bcl6b.2, Klf7.1, Zfp410.1, Zfp281.2, Egr1.1, Smad3.1, Zfp740.1, Sp4.1, Ascl2.2, Zif268.1	0.00000014	TTTYTTNYTTNT	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.16	GACGCG	NA	1.19	GCGGNCGC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.46	CGACGG	NA	NA	0.5	ATTAGGGT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-692	0.794118	0.0000523

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-466l-3p	0.583333	0.0000662

100503422 predicted gene, 19684 Details for - - predicted gene, 19684 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503422 Tuberculist Genomic Region	15200 chemokine (C-X-C motif) ligand 1 Details for - - chemokine (C-X-C motif) ligand 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14825 Tuberculist Genomic Region
15277 heparin-binding EGF-like growth factor Details for - - heparin-binding EGF-like growth factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15200 Tuberculist Genomic Region	18124 hexokinase 2 Details for - - hexokinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15277 Tuberculist Genomic Region
19073 nuclear receptor subfamily 4, group A, member 3 Details for RP23-122N18.2 - nuclear receptor subfamily 4, group A, member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18124 Tuberculist Genomic Region	195209 serglycin Details for - - serglycin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19073 Tuberculist Genomic Region
19696 predicted gene 22 Details for - - predicted gene 22 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 195209 Tuberculist Genomic Region	20299 reticuloendotheliosis oncogene Details for - - reticuloendotheliosis oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19696 Tuberculist Genomic Region
214150 chemokine (C-C motif) ligand 22 Details for - - chemokine (C-C motif) ligand 22 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20299 Tuberculist Genomic Region	215418 argonaute RISC catalytic subunit 3 Details for RP23-113P22.6 - argonaute RISC catalytic subunit 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 214150 Tuberculist Genomic Region
231207 cysteine-serine-rich nuclear protein 1 Details for - - cysteine-serine-rich nuclear protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 215418 Tuberculist Genomic Region	236285 cytoplasmic polyadenylation element binding protein 2 Details for - - cytoplasmic polyadenylation element binding protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231207 Tuberculist Genomic Region
241694 LanC lantibiotic synthetase component C-like 3 (bacterial) Details for RP23-423L11.1 - LanC lantibiotic synthetase component C-like 3 (bacterial) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 236285 Tuberculist Genomic Region	242509 Ral GTPase activating protein, alpha subunit 2 (catalytic) Details for RP23-185F7.2 - Ral GTPase activating protein, alpha subunit 2 (catalytic) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241694 Tuberculist Genomic Region
244668 basonuclin 2 Details for RP23-229A22.1 - basonuclin 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 242509 Tuberculist Genomic Region	246083 signal-induced proliferation-associated 1 like 2 Details for - - signal-induced proliferation-associated 1 like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 244668 Tuberculist Genomic Region
26397 defensin beta 13 Details for AL590619.7 - defensin beta 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 246083 Tuberculist Genomic Region	320878 mitogen-activated protein kinase kinase 3 Details for RP23-467E19.1 - mitogen-activated protein kinase kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26397 Tuberculist Genomic Region
330096 microtubule associated monooxygenase, calponin and LIM domain containing 2 Details for - - microtubule associated monooxygenase, calponin and LIM domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320878 Tuberculist Genomic Region	380921 shisa homolog 3 (Xenopus laevis) Details for - - shisa homolog 3 (Xenopus laevis) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 330096 Tuberculist Genomic Region
382695 diacylglycerol kinase, eta Details for mCG_120030 - diacylglycerol kinase, eta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 380921 Tuberculist Genomic Region	50772 immunoglobulin heavy variable 1-56 Details for - - immunoglobulin heavy variable 1-56 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 382695 Tuberculist Genomic Region
55948 mitogen-activated protein kinase 6 Details for - - mitogen-activated protein kinase 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 50772 Tuberculist Genomic Region	56193 stratifin Details for RP23-137L22.11-001 - stratifin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 55948 Tuberculist Genomic Region
66878 pleckstrin Details for RP23-348N2.1 - pleckstrin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56193 Tuberculist Genomic Region	67338 RIO kinase 3 Details for - - RIO kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66878 Tuberculist Genomic Region
67533 ring finger and FYVE like domain containing protein Details for RP23-316C11.8 - ring finger and FYVE like domain containing protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67338 Tuberculist Genomic Region	68567 PTPRF interacting protein, binding protein 1 (liprin beta 1) Details for - - PTPRF interacting protein, binding protein 1 (liprin beta 1) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67533 Tuberculist Genomic Region
68949 cell growth regulator with EF hand domain 1 Details for - - cell growth regulator with EF hand domain 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68567 Tuberculist Genomic Region	69660 RIKEN cDNA 1500012F01 gene Details for - - RIKEN cDNA 1500012F01 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68949 Tuberculist Genomic Region
723909 transmembrane BAX inhibitor motif containing 1 Details for - - transmembrane BAX inhibitor motif containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69660 Tuberculist Genomic Region	74120 microRNA 342 Details for - - microRNA 342 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 723909 Tuberculist Genomic Region
74427 zinc finger protein 263 Details for - - zinc finger protein 263 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74120 Tuberculist Genomic Region	75646 ELL associated factor 1 Details for - - ELL associated factor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74427 Tuberculist Genomic Region
75869 retinoic acid induced 14 Details for - - retinoic acid induced 14 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75646 Tuberculist Genomic Region	80859 ADP-ribosylation factor-like 5B Details for - - ADP-ribosylation factor-like 5B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75869 Tuberculist Genomic Region
99633 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80859 Tuberculist Genomic Region	240396 latrophilin 2 Details for - - latrophilin 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99633 Tuberculist Genomic Region
54604 mex3 homolog C (C. elegans) Details for - - mex3 homolog C (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240396 Tuberculist Genomic Region	11847 pecanex homolog (Drosophila) Details for - - pecanex homolog (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54604 Tuberculist Genomic Region
20448 arginase type II Details for - - arginase type II GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11847 Tuberculist Genomic Region	217151 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 Details for RP23-17P12.1 - ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20448 Tuberculist Genomic Region
192656 ADP-ribosylation factor-like 5C Details for RP23-309H19.3 - ADP-ribosylation factor-like 5C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217151 Tuberculist Genomic Region	24088 receptor (TNFRSF)-interacting serine-threonine kinase 2 Details for RP23-378L22.1 - receptor (TNFRSF)-interacting serine-threonine kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 192656 Tuberculist Genomic Region
320790 toll-like receptor 2 Details for - - toll-like receptor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 24088 Tuberculist Genomic Region	76650 chromodomain helicase DNA binding protein 7 Details for RP23-464N23.1 - chromodomain helicase DNA binding protein 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320790 Tuberculist Genomic Region
Details for - - sulfiredoxin 1 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76650 Tuberculist Genomic Region

Summary

Members

Details for - - predicted gene, 19684

Details for - - chemokine (C-X-C motif) ligand 1

Details for - - heparin-binding EGF-like growth factor

Details for - - hexokinase 2

Details for RP23-122N18.2 - nuclear receptor subfamily 4, group A, member 3

Details for - - serglycin

Details for - - predicted gene 22

Details for - - reticuloendotheliosis oncogene

Details for - - chemokine (C-C motif) ligand 22

Details for RP23-113P22.6 - argonaute RISC catalytic subunit 3

Details for - - cysteine-serine-rich nuclear protein 1

Details for - - cytoplasmic polyadenylation element binding protein 2

Details for RP23-423L11.1 - LanC lantibiotic synthetase component C-like 3 (bacterial)

Details for RP23-185F7.2 - Ral GTPase activating protein, alpha subunit 2 (catalytic)

Details for RP23-229A22.1 - basonuclin 2

Details for - - signal-induced proliferation-associated 1 like 2

Details for AL590619.7 - defensin beta 13

Details for RP23-467E19.1 - mitogen-activated protein kinase kinase 3

Details for - - microtubule associated monooxygenase, calponin and LIM domain containing 2

Details for - - shisa homolog 3 (Xenopus laevis)

Details for mCG_120030 - diacylglycerol kinase, eta

Details for - - immunoglobulin heavy variable 1-56

Details for - - mitogen-activated protein kinase 6

Details for RP23-137L22.11-001 - stratifin

Details for RP23-348N2.1 - pleckstrin

Details for - - RIO kinase 3

Details for RP23-316C11.8 - ring finger and FYVE like domain containing protein

Details for - - PTPRF interacting protein, binding protein 1 (liprin beta 1)

Details for - - cell growth regulator with EF hand domain 1

Details for - - RIKEN cDNA 1500012F01 gene

Details for - - transmembrane BAX inhibitor motif containing 1

Details for - - microRNA 342

Details for - - zinc finger protein 263

Details for - - ELL associated factor 1

Details for - - retinoic acid induced 14

Details for - - ADP-ribosylation factor-like 5B

Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta

Details for - - latrophilin 2

Details for - - mex3 homolog C (C. elegans)

Details for - - pecanex homolog (Drosophila)

Details for - - arginase type II

Details for RP23-17P12.1 - ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

Details for RP23-309H19.3 - ADP-ribosylation factor-like 5C

Details for RP23-378L22.1 - receptor (TNFRSF)-interacting serine-threonine kinase 2

Details for - - toll-like receptor 2

Details for RP23-464N23.1 - chromodomain helicase DNA binding protein 7

Details for - - sulfiredoxin 1 homolog (S. cerevisiae)

GO Terms

3p UTR PITA