PITA_33 megaCluster: 1 Residual: 0.08 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_33	1	0.08	6	0	0.645649	0.962

Members

Displaying 1 - 35 of 35

14102 Fas (TNF receptor superfamily member 6) Details for - - Fas (TNF receptor superfamily member 6) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14102 Tuberculist Genomic Region	14696 guanine nucleotide binding protein (G protein), beta 4 Details for - - guanine nucleotide binding protein (G protein), beta 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14696 Tuberculist Genomic Region
14766 G protein-coupled receptor 56 Details for - - G protein-coupled receptor 56 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14766 Tuberculist Genomic Region	15901 inhibitor of DNA binding 1 Details for RP23-106A3.1 - inhibitor of DNA binding 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15901 Tuberculist Genomic Region
15903 inhibitor of DNA binding 3 Details for RP23-118A9.1 - inhibitor of DNA binding 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15903 Tuberculist Genomic Region	16438 inositol 1,4,5-trisphosphate receptor 1 Details for - - inositol 1,4,5-trisphosphate receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16438 Tuberculist Genomic Region
170716 cytochrome P450, family 4, subfamily f, polypeptide 13 Details for - - cytochrome P450, family 4, subfamily f, polypeptide 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170716 Tuberculist Genomic Region	17873 growth arrest and DNA-damage-inducible 45 beta Details for - - growth arrest and DNA-damage-inducible 45 beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17873 Tuberculist Genomic Region
18034 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18034 Tuberculist Genomic Region	18414 oncostatin M receptor Details for - - oncostatin M receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18414 Tuberculist Genomic Region
18590 platelet derived growth factor, alpha Details for - - platelet derived growth factor, alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18590 Tuberculist Genomic Region	18591 platelet derived growth factor, B polypeptide Details for - - platelet derived growth factor, B polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18591 Tuberculist Genomic Region
20239 ataxin 2 Details for - - ataxin 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20239 Tuberculist Genomic Region	20299 chemokine (C-C motif) ligand 22 Details for - - chemokine (C-C motif) ligand 22 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20299 Tuberculist Genomic Region
20448 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 Details for RP23-17P12.1 - ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20448 Tuberculist Genomic Region	230752 eva-1 homolog B (C. elegans) Details for RP23-365D10.2 - eva-1 homolog B (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230752 Tuberculist Genomic Region
235380 Dmx-like 2 Details for RP24-383M20.1 - Dmx-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 235380 Tuberculist Genomic Region	286940 filamin, beta Details for - - filamin, beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 286940 Tuberculist Genomic Region
29815 breast cancer anti-estrogen resistance 3 Details for - - breast cancer anti-estrogen resistance 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 29815 Tuberculist Genomic Region	320129 adrenergic receptor kinase, beta 2 Details for - - adrenergic receptor kinase, beta 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320129 Tuberculist Genomic Region
628746 predicted gene 6910 Details for - - predicted gene 6910 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 628746 Tuberculist Genomic Region	66610 ABI gene family, member 3 Details for RP23-151M22.4 - ABI gene family, member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66610 Tuberculist Genomic Region
71720 oxysterol binding protein-like 3 Details for - - oxysterol binding protein-like 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71720 Tuberculist Genomic Region	71973 RNA binding protein with multiple splicing 2 Details for - - RNA binding protein with multiple splicing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71973 Tuberculist Genomic Region
72536 T cell activation Rho GTPase activating protein Details for - - T cell activation Rho GTPase activating protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72536 Tuberculist Genomic Region	72565 uveal autoantigen with coiled-coil domains and ankyrin repeats Details for - - uveal autoantigen with coiled-coil domains and ankyrin repeats GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72565 Tuberculist Genomic Region
74257 tetraspanin 17 Details for - - tetraspanin 17 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74257 Tuberculist Genomic Region	75869 ADP-ribosylation factor-like 5B Details for - - ADP-ribosylation factor-like 5B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75869 Tuberculist Genomic Region
80859 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80859 Tuberculist Genomic Region	99633 latrophilin 2 Details for - - latrophilin 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99633 Tuberculist Genomic Region
11847 arginase type II Details for - - arginase type II GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11847 Tuberculist Genomic Region	12504 CD4 antigen Details for - - CD4 antigen GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12504 Tuberculist Genomic Region
387609 zinc fingers and homeoboxes 2 Details for - - zinc fingers and homeoboxes 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 387609 Tuberculist Genomic Region	108078 oxidized low density lipoprotein (lectin-like) receptor 1 Details for - - oxidized low density lipoprotein (lectin-like) receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108078 Tuberculist Genomic Region
71409 formin-like 2 Details for RP23-282A22.1 - formin-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71409 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_GLI2_01_M01703	0.470588	0.00000493

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000016	NCCCCRCCCCC	SP1_MA0079.2, Klf4_MA0039.2, V$ZFP281_01_M01597, V$SP4_Q5_M01273, V$SP1_03_M02281, V$SP1_02_M01303, V$UF1H3BETA_Q6_M01068, V$SP1_Q2_01_M00933, V$SP1_Q4_01_M00932, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$MAZR_01_M00491, V$ZFP281_04_M02831, V$ZNF219_01_M01122, V$CKROX_Q2_M01175, V$ZBP89_Q4_M01816, V$CACBINDINGPROTEIN_Q6_M00720, V$MAZ_Q6_01_M02023, V$GKLF_02_M01588, V$GC_01_M00255, V$MAZ_Q6_M00649, V$SP4_03_M02810, V$EKLF_Q5_M01874, V$CACD_01_M01113, V$KLF7_03_M02773, V$SP1SP3_Q4_M01219, V$FKLF_Q5_M01837, V$BCL6B_04_M02844, V$KLF15_Q2_M01714, V$EGR1_Q6_M01873, V$ZFP740_03_M02834, V$KROX_Q6_M00982, V$EGR1_06_M02744, V$ETF_Q6_M00695, V$GLI3_Q5_01_M01657, V$EGR_Q6_M00807, V$SMAD4_04_M02898, V$WT1_Q6_M01118, V$MZF1_02_M00084, V$ZFP410_04_M02936, V$MZF1_01_M00083, V$CACCCBINDINGFACTOR_Q6_M00721, V$SP1_01_M00008, V$E2F3_Q6_M02089, V$WT1_Q6_01_M02036, V$CHCH_01_M00986, V$SOX14_04_M02901, V$EGR2_Q6_M02092, Zfp281.2, Sp4.1, Klf7.1, Bcl6b.2, Zfp740.1, Egr1.1, Smad3.1, Zfp410.1, Sox13.2, Ascl2.2, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, SP8_C2H2_DBD_monomeric_12_1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, Zfp740_C2H2_DBD_monomeric_10_1	0.000067	AAAAAWAAAAAA	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.14	GCGCTG	NA	1.18	CGGCCCCN	V$ZFP410_04_M02936, V$BCL6B_04_M02844, Zfp410.1, Bcl6b.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.74	CGGTCG	NA	NA	0.79	CGTCGCGG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-344e	0.16129	0.00002

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