PITA_58 megaCluster: 2 Residual: 0.20 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_58	2	0.20	14	0	0.89782	0

Members

Displaying 1 - 24 of 24

100504169 predicted gene, 20098 Details for - - predicted gene, 20098 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504169 Tuberculist Genomic Region	104252 CDC42 effector protein (Rho GTPase binding) 2 Details for - - CDC42 effector protein (Rho GTPase binding) 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104252 Tuberculist Genomic Region
12986 colony stimulating factor 3 receptor (granulocyte) Details for RP23-140F18.1 - colony stimulating factor 3 receptor (granulocyte) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12986 Tuberculist Genomic Region	16180 interleukin 1 receptor accessory protein Details for - - interleukin 1 receptor accessory protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16180 Tuberculist Genomic Region
17357 MARCKS-like 1 Details for RP23-209C6.6 - MARCKS-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17357 Tuberculist Genomic Region	209200 deltex 3-like (Drosophila) Details for - - deltex 3-like (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209200 Tuberculist Genomic Region
22323 vasodilator-stimulated phosphoprotein Details for - - vasodilator-stimulated phosphoprotein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22323 Tuberculist Genomic Region	22695 zinc finger protein 36 Details for - - zinc finger protein 36 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22695 Tuberculist Genomic Region
22778 IKAROS family zinc finger 1 Details for RP23-373H2.2 - IKAROS family zinc finger 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22778 Tuberculist Genomic Region	231991 cAMP responsive element binding protein 5 Details for - - cAMP responsive element binding protein 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231991 Tuberculist Genomic Region
320404 inositol 1,4,5-trisphosphate 3-kinase B Details for - - inositol 1,4,5-trisphosphate 3-kinase B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320404 Tuberculist Genomic Region	432702 immunoglobulin heavy variable 1-4 Details for - - immunoglobulin heavy variable 1-4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 432702 Tuberculist Genomic Region
56501 E74-like factor 4 (ets domain transcription factor) Details for RP23-260P5.2 - E74-like factor 4 (ets domain transcription factor) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56501 Tuberculist Genomic Region	58185 radical S-adenosyl methionine domain containing 2 Details for - - radical S-adenosyl methionine domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 58185 Tuberculist Genomic Region
627049 zinc finger protein 800 Details for - - zinc finger protein 800 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 627049 Tuberculist Genomic Region	68074 RIKEN cDNA A930013F10 gene Details for - - RIKEN cDNA A930013F10 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68074 Tuberculist Genomic Region
780818 immunoglobulin heavy variable V11-2 Details for - - immunoglobulin heavy variable V11-2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 780818 Tuberculist Genomic Region	100503094 predicted gene, 19551 Details for - - predicted gene, 19551 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503094 Tuberculist Genomic Region
18729 paired-Ig-like receptor A6 Details for - - paired-Ig-like receptor A6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18729 Tuberculist Genomic Region	383619 absent in melanoma 2 Details for - - absent in melanoma 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 383619 Tuberculist Genomic Region
54216 protocadherin 7 Details for - - protocadherin 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54216 Tuberculist Genomic Region	69104 membrane-associated ring finger (C3HC4) 5 Details for - - membrane-associated ring finger (C3HC4) 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69104 Tuberculist Genomic Region
71586 interferon induced with helicase C domain 1 Details for RP23-34J8.2 - interferon induced with helicase C domain 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71586 Tuberculist Genomic Region	80750 NEDD4 binding protein 1 Details for - - NEDD4 binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80750 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_ISGF3G_03_M02771	0.368421	0.0000000541

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000018	ANTTTNTTTTTT	NA	5.9	GGGGGCGGGGA	SP1_MA0079.2, Klf4_MA0039.2, MZF1_1-4_MA0056.1, SP1_MA0079.1, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$SP1_03_M02281, V$ZFP281_01_M01597, V$SP1_Q6_M00196, V$SP1_02_M01303, V$SP1_Q6_01_M00931, V$SP1_Q4_01_M00932, V$MAZ_Q6_01_M02023, V$UF1H3BETA_Q6_M01068, V$CKROX_Q2_M01175, V$KLF7_03_M02773, V$MAZR_01_M00491, V$GC_01_M00255, V$MAZ_Q6_M00649, V$ZBP89_Q4_M01816, V$SP1SP3_Q4_M01219, V$ZFP281_04_M02831, V$SP4_03_M02810, V$EGR1_Q6_M01873, V$SP1_01_M00008, V$GKLF_02_M01588, V$ETF_Q6_M00695, V$ZNF219_01_M01122, V$KROX_Q6_M00982, V$BCL6B_04_M02844, V$EGR1_06_M02744, V$CACD_01_M01113, V$E2F3_Q6_M02089, V$WT1_Q6_01_M02036, V$ZFP410_04_M02936, V$MZF1_01_M00083, V$ZFP740_03_M02834, V$SMAD4_04_M02898, V$CACBINDINGPROTEIN_Q6_M00720, V$EKLF_Q5_M01874, V$KLF15_Q2_M01714, V$FKLF_Q5_M01837, V$WT1_Q6_M01118, V$SP2_01_M01783, Klf7.1, Zfp281.2, Sp4.1, Egr1.1, Bcl6b.2, Zfp410.1, Zfp740.1, Smad3.1, Zif268.1, Ascl2.2, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, SP8_C2H2_DBD_monomeric_12_1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.52	NRGCGGGG	Zfp740.2, Egr1.1, Smad3.1, Rara.2		NA	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.53	TTTCNC	NA	NA	0.66	GCAATCAC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-17, mmu-miR-20b, mmu-miR-20a, mmu-miR-106a, mmu-miR-106b, mmu-miR-93	0.866667	0.0000327

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-672	0.529412	0.00000505

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