PITA_68 megaCluster: 2 Residual: 0.27 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_68	2	0.27	15	0.001	0.864659	0

Members

Displaying 1 - 31 of 31

100504230 expressed sequence AU020206 Details for - - expressed sequence AU020206 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504230 Tuberculist Genomic Region	11982 ATPase, class V, type 10A Details for - - ATPase, class V, type 10A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11982 Tuberculist Genomic Region
13011 cystatin F (leukocystatin) Details for RP23-156P22.1 - cystatin F (leukocystatin) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13011 Tuberculist Genomic Region	16175 interleukin 1 alpha Details for RP23-160G19.8 - interleukin 1 alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16175 Tuberculist Genomic Region
17131 SMAD family member 7 Details for - - SMAD family member 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17131 Tuberculist Genomic Region	17355 AF4/FMR2 family, member 1 Details for AL731554.2 - AF4/FMR2 family, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17355 Tuberculist Genomic Region
19731 ral guanine nucleotide dissociation stimulator,-like 1 Details for - - ral guanine nucleotide dissociation stimulator,-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19731 Tuberculist Genomic Region	21354 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) Details for - - transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21354 Tuberculist Genomic Region
21355 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) Details for RP23-123G8.1 - transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21355 Tuberculist Genomic Region	21810 transforming growth factor, beta induced Details for - - transforming growth factor, beta induced GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21810 Tuberculist Genomic Region
237886 schlafen 9 Details for RP23-392I13.10-002 - schlafen 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 237886 Tuberculist Genomic Region	23882 growth arrest and DNA-damage-inducible 45 gamma Details for - - growth arrest and DNA-damage-inducible 45 gamma GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23882 Tuberculist Genomic Region
239122 SET domain, bifurcated 2 Details for mCG_13852 - SET domain, bifurcated 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 239122 Tuberculist Genomic Region	246779 interleukin 27 Details for - - interleukin 27 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 246779 Tuberculist Genomic Region
29810 BCL2-associated athanogene 3 Details for MNCb-2243 - BCL2-associated athanogene 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 29810 Tuberculist Genomic Region	66665 Myb/SANT-like DNA-binding domain containing 3 Details for RP23-320C6.1 - Myb/SANT-like DNA-binding domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66665 Tuberculist Genomic Region
67092 glycine amidinotransferase (L-arginine:glycine amidinotransferase) Details for RP23-101F14.1 - glycine amidinotransferase (L-arginine:glycine amidinotransferase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67092 Tuberculist Genomic Region	67446 dual specificity phosphatase 28 Details for - - dual specificity phosphatase 28 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67446 Tuberculist Genomic Region
80287 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 Details for - - apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80287 Tuberculist Genomic Region	107569 5'-nucleotidase, cytosolic III Details for - - 5'-nucleotidase, cytosolic III GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107569 Tuberculist Genomic Region
14042 exostoses (multiple) 1 Details for - - exostoses (multiple) 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14042 Tuberculist Genomic Region	16891 lipase, endothelial Details for - - lipase, endothelial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16891 Tuberculist Genomic Region
20821 tripartite motif-containing 21 Details for - - tripartite motif-containing 21 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20821 Tuberculist Genomic Region	21939 CD40 antigen Details for RP23-428M13.1 - CD40 antigen GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21939 Tuberculist Genomic Region
240047 matrix metallopeptidase 25 Details for - - matrix metallopeptidase 25 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240047 Tuberculist Genomic Region	52552 poly (ADP-ribose) polymerase family, member 8 Details for - - poly (ADP-ribose) polymerase family, member 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52552 Tuberculist Genomic Region
60504 interleukin 21 receptor Details for - - interleukin 21 receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 60504 Tuberculist Genomic Region	628705 PHD finger protein 11C Details for mCG_1037415 - PHD finger protein 11C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 628705 Tuberculist Genomic Region
18035 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18035 Tuberculist Genomic Region	21817 transglutaminase 2, C polypeptide Details for RP23-396G1.2 - transglutaminase 2, C polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21817 Tuberculist Genomic Region
229898 guanylate binding protein 5 Details for - - guanylate binding protein 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229898 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_ISGF3G_03_M02771	0.333333	0.000000000938

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000000028	TTTCNNTTTCY	IRF1_MA0050.1, STAT1_MA0137.1, IRF2_MA0051.1, V$IRF2_Q6_M01882, V$IRF_Q6_01_M00972, V$ISRE_01_M00258, V$IRF7_01_M00453, V$IRF1_Q6_01_M01881, V$IRF_Q6_M00772, IRF7_IRF_DBD_dimeric_14_1, IRF5_IRF_full_dimeric_14_1, PRDM1_C2H2_full_monomeric-or-dimeric_15_1	3.2	GRGGGGNGGGGA	SP1_MA0079.2, Klf4_MA0039.2, MZF1_1-4_MA0056.1, V$ZFP281_01_M01597, V$SP1_02_M01303, V$CKROX_Q2_M01175, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$SP1_03_M02281, V$MAZR_01_M00491, V$UF1H3BETA_Q6_M01068, V$MAZ_Q6_M00649, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$MAZ_Q6_01_M02023, V$GKLF_02_M01588, V$CACBINDINGPROTEIN_Q6_M00720, V$ZFP281_04_M02831, V$ZBP89_Q4_M01816, V$KLF7_03_M02773, V$MZF1_01_M00083, V$CACD_01_M01113, V$GC_01_M00255, V$ZNF219_01_M01122, V$FKLF_Q5_M01837, V$KLF15_Q2_M01714, V$SP1SP3_Q4_M01219, V$ZFP740_03_M02834, V$BCL6B_04_M02844, V$EKLF_Q5_M01874, V$MZF1_Q5_M01733, V$SMAD4_04_M02898, V$ETF_Q6_M00695, V$SOX14_04_M02901, V$SP1_01_M00008, Zfp281.2, Klf7.1, Zfp740.1, Bcl6b.2, Smad3.1, Sox13.2, Zfp410.1, Sp4.1, Egr1.1, Ascl2.2, SP1_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, FOXO6_forkhead_DBD_putatively-multimeric_14_1, SP3_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
0.97	TGCCGA	NA	1.24	TGGCGCGA	V$E2F_Q2_M00803, V$E2F_Q6_01_M00920, V$E2F1_Q3_01_M00938, V$E2F_03_M00516, V$E2F_Q4_01_M00919, V$SMAD4_04_M02898, V$E2F3_Q6_M02089, V$E2F_Q4_02_M00939, V$E2F_Q3_01_M00918, Smad3.1, E2F3.2, E2F2.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.68	CGCTCG	NA	NA	0.92	TAGCCGNG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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