PITA_88 megaCluster: 11 Residual: 0.26

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_88	11	0.26	9	0	0.703369	0.604

Members

Displaying 1 - 39 of 39

TFBS DB TF

TFs	percTargets	pValue
IRF5_IRF_full_dimeric_14_1	0.210526	0.00004

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00011	AWAWRAAARAW	NA	680	GGGCGGGGCNNG	Klf4_MA0039.2, SP1_MA0079.2, V$KLF7_03_M02773, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$GC_01_M00255, V$SP1_Q4_01_M00932, V$SP4_Q5_M01273, V$GKLF_02_M01588, V$SP1_Q2_01_M00933, V$MAZR_01_M00491, V$SP1_02_M01303, V$SP2_01_M01783, V$SMAD4_04_M02898, V$SP4_04_M02914, V$E2F3_Q6_M02089, V$ZFP281_01_M01597, V$UF1H3BETA_Q6_M01068, V$CACD_01_M01113, V$SP1_03_M02281, V$SP1_01_M00008, V$SP4_03_M02810, V$ASCL2_04_M02841, V$CKROX_Q2_M01175, V$ZFP740_03_M02834, V$EKLF_Q5_M01874, V$ZNF219_01_M01122, V$KROX_Q6_M00982, V$ZFP281_04_M02831, V$MAZ_Q6_01_M02023, V$MAZ_Q6_M00649, V$BCL6B_04_M02844, V$ZFP410_04_M02936, V$CNOT3_01_M01253, V$EGR1_Q6_M01873, V$ZBP89_Q4_M01816, Klf7.1, Smad3.1, Sp4.2, Sp4.1, Zfp740.1, Ascl2.2, Zfp281.2, Bcl6b.2, Egr1.1, Zfp410.1, Zif268.1, Sox13.2, Klf7.2, Zfp161.2, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP1_C2H2_DBD_monomeric_11_1, Klf12_C2H2_DBD_monomeric_15_1, KLF13_C2H2_full_monomeric_18_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.12	NKGCGCGG	Zfp161.2, Zif268.1, Egr1.1		NA	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.71	CGTCCG	NA	NA	0.66	GCNATCAC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

100952 elastin microfibril interfacer 1 Details for - - elastin microfibril interfacer 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100952 Tuberculist Genomic Region	11749 annexin A6 Details for - - annexin A6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11749 Tuberculist Genomic Region
12021 BRCA1 associated RING domain 1 Details for - - BRCA1 associated RING domain 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12021 Tuberculist Genomic Region	13433 DNA methyltransferase (cytosine-5) 1 Details for - - DNA methyltransferase (cytosine-5) 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13433 Tuberculist Genomic Region
16413 integrin beta 1 binding protein 1 Details for - - integrin beta 1 binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16413 Tuberculist Genomic Region	18452 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide Details for RP23-309E16.6 - procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18452 Tuberculist Genomic Region
19182 proteasome (prosome, macropain) 26S subunit, ATPase 3 Details for RP23-263H8.1 - proteasome (prosome, macropain) 26S subunit, ATPase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19182 Tuberculist Genomic Region	192156 mevalonate (diphospho) decarboxylase Details for - - mevalonate (diphospho) decarboxylase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 192156 Tuberculist Genomic Region
21881 transketolase Details for - - transketolase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21881 Tuberculist Genomic Region	21898 toll-like receptor 4 Details for RP24-209H15.1 - toll-like receptor 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21898 Tuberculist Genomic Region
21917 thymopoietin Details for - - thymopoietin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21917 Tuberculist Genomic Region	234736 ring finger and WD repeat domain 3 Details for - - ring finger and WD repeat domain 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234736 Tuberculist Genomic Region
27419 alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) Details for - - alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27419 Tuberculist Genomic Region	381062 ER membrane associated RNA degradation Details for - - ER membrane associated RNA degradation GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381062 Tuberculist Genomic Region
53331 syntaxin 7 Details for - - syntaxin 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53331 Tuberculist Genomic Region	56043 aldo-keto reductase family 1, member E1 Details for - - aldo-keto reductase family 1, member E1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56043 Tuberculist Genomic Region
63913 family with sequence similarity 129, member A Details for - - family with sequence similarity 129, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 63913 Tuberculist Genomic Region	69263 replication factor C (activator 1) 3 Details for - - replication factor C (activator 1) 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69263 Tuberculist Genomic Region
69399 RIKEN cDNA 1700025G04 gene Details for - - RIKEN cDNA 1700025G04 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69399 Tuberculist Genomic Region	69716 thyroid hormone receptor interactor 13 Details for - - thyroid hormone receptor interactor 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69716 Tuberculist Genomic Region
71728 serine/threonine kinase 11 interacting protein Details for - - serine/threonine kinase 11 interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71728 Tuberculist Genomic Region	71862 G protein-coupled receptor 160 Details for - - G protein-coupled receptor 160 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71862 Tuberculist Genomic Region
71876 centromere protein U Details for - - centromere protein U GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71876 Tuberculist Genomic Region	72674 adiponectin receptor 1 Details for - - adiponectin receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72674 Tuberculist Genomic Region
76263 glutathione S-transferase kappa 1 Details for - - glutathione S-transferase kappa 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76263 Tuberculist Genomic Region	76454 F-box protein 31 Details for MNCb-2609 - F-box protein 31 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76454 Tuberculist Genomic Region
104184 bleomycin hydrolase Details for RP23-100P23.3 - bleomycin hydrolase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104184 Tuberculist Genomic Region	16162 interleukin 12 receptor, beta 2 Details for - - interleukin 12 receptor, beta 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16162 Tuberculist Genomic Region
17312 C-type lectin domain family 10, member A Details for DN-160I24.1 - C-type lectin domain family 10, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17312 Tuberculist Genomic Region	21856 translocase of inner mitochondrial membrane 44 Details for - - translocase of inner mitochondrial membrane 44 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21856 Tuberculist Genomic Region
245866 intraflagellar transport 52 Details for RP23-335N12.4 - intraflagellar transport 52 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245866 Tuberculist Genomic Region	58911 sulfatase modifying factor 1 Details for - - sulfatase modifying factor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 58911 Tuberculist Genomic Region
66877 Crn, crooked neck-like 1 (Drosophila) Details for RP23-125A1.4 - Crn, crooked neck-like 1 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66877 Tuberculist Genomic Region	66972 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 Details for - - solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66972 Tuberculist Genomic Region
67097 ribosomal protein S10 Details for RP24-535O17.1 - ribosomal protein S10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67097 Tuberculist Genomic Region	67903 GIPC PDZ domain containing family, member 1 Details for - - GIPC PDZ domain containing family, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67903 Tuberculist Genomic Region
74048 RIKEN cDNA 4632428N05 gene Details for - - RIKEN cDNA 4632428N05 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74048 Tuberculist Genomic Region	74551 phosphoenolpyruvate carboxykinase 2 (mitochondrial) Details for - - phosphoenolpyruvate carboxykinase 2 (mitochondrial) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74551 Tuberculist Genomic Region
69125 CCR4-NOT transcription complex, subunit 8 Details for RP23-293I3.1 - CCR4-NOT transcription complex, subunit 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69125 Tuberculist Genomic Region

Summary

Members

Details for - - elastin microfibril interfacer 1

Details for - - annexin A6

Details for - - BRCA1 associated RING domain 1

Details for - - DNA methyltransferase (cytosine-5) 1

Details for - - integrin beta 1 binding protein 1

Details for RP23-309E16.6 - procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide

Details for RP23-263H8.1 - proteasome (prosome, macropain) 26S subunit, ATPase 3

Details for - - mevalonate (diphospho) decarboxylase

Details for - - transketolase

Details for RP24-209H15.1 - toll-like receptor 4

Details for - - thymopoietin

Details for - - ring finger and WD repeat domain 3

Details for - - alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)

Details for - - ER membrane associated RNA degradation

Details for - - syntaxin 7

Details for - - aldo-keto reductase family 1, member E1

Details for - - family with sequence similarity 129, member A

Details for - - replication factor C (activator 1) 3

Details for - - RIKEN cDNA 1700025G04 gene

Details for - - thyroid hormone receptor interactor 13

Details for - - serine/threonine kinase 11 interacting protein

Details for - - G protein-coupled receptor 160

Details for - - centromere protein U

Details for - - adiponectin receptor 1

Details for - - glutathione S-transferase kappa 1

Details for MNCb-2609 - F-box protein 31

Details for RP23-100P23.3 - bleomycin hydrolase

Details for - - interleukin 12 receptor, beta 2

Details for DN-160I24.1 - C-type lectin domain family 10, member A

Details for - - translocase of inner mitochondrial membrane 44

Details for RP23-335N12.4 - intraflagellar transport 52

Details for - - sulfatase modifying factor 1

Details for RP23-125A1.4 - Crn, crooked neck-like 1 (Drosophila)

Details for - - solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23

Details for RP24-535O17.1 - ribosomal protein S10

Details for - - GIPC PDZ domain containing family, member 1

Details for - - RIKEN cDNA 4632428N05 gene

Details for - - phosphoenolpyruvate carboxykinase 2 (mitochondrial)

Details for RP23-293I3.1 - CCR4-NOT transcription complex, subunit 8

GO Terms

3p UTR PITA