PITA_90 megaCluster: 8 Residual: 0.22

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_90	8	0.22	12	0	0.807472	0.002

Members

Displaying 1 - 39 of 39

TFBS DB TF

TFs	percTargets	pValue
V_FXR_Q3_M00631	0.184211	0.0000124

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000047	GCCMCGCCCCY	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$SP1_Q6_M00196, V$KLF7_03_M02773, V$SP1_Q6_01_M00931, V$SP4_Q5_M01273, V$GC_01_M00255, V$SP1_Q2_01_M00933, V$SP1_Q4_01_M00932, V$GKLF_02_M01588, V$SP1_02_M01303, V$SP4_03_M02810, V$SP2_01_M01783, V$SP1_01_M00008, V$SP1_03_M02281, V$UF1H3BETA_Q6_M01068, V$ZFP281_01_M01597, V$MAZR_01_M00491, V$E2F3_Q6_M02089, V$SMAD4_04_M02898, V$SP4_04_M02914, V$CKROX_Q2_M01175, V$CACD_01_M01113, V$KLF15_Q2_M01714, V$MAZ_Q6_M00649, V$ZFP281_04_M02831, V$SP1SP3_Q4_M01219, V$MAZ_Q6_01_M02023, V$KROX_Q6_M00982, V$EGR1_Q6_M01873, V$ETF_Q6_M00695, V$BCL6B_04_M02844, V$WT1_Q6_01_M02036, V$EGR1_06_M02744, V$ZFP740_03_M02834, V$ZFP410_04_M02936, V$EKLF_Q5_M01874, V$WT1_Q6_M01118, V$ZNF219_01_M01122, V$ZBP89_Q4_M01816, Klf7.1, Sp4.1, Smad3.1, Sp4.2, Zfp281.2, Bcl6b.2, Egr1.1, Zfp410.1, Zfp740.1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP3_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, KLF13_C2H2_full_monomeric_18_1, SP8_C2H2_DBD_monomeric_12_1, Klf12_C2H2_DBD_monomeric_15_1	0.018	YTTTCYTTCTT	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.16	TCGACG	NA	1.25	KCGGGGCG	V$BCL6B_04_M02844, V$ZFP410_04_M02936, V$SP1_Q6_M00196, V$SP1_Q2_01_M00933, V$SP4_Q5_M01273, V$SP1_Q6_01_M00931, Bcl6b.2, Zfp410.1, Zfp740.2, Klf7.1, Klf7.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.43	GTGYGT	NA	NA	0.68	GTGNGTCA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

100900 HscB iron-sulfur cluster co-chaperone homolog (E. coli) Details for - - HscB iron-sulfur cluster co-chaperone homolog (E. coli) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100900 Tuberculist Genomic Region	107476 acetyl-Coenzyme A carboxylase alpha Details for RP23-123O10.1 - acetyl-Coenzyme A carboxylase alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107476 Tuberculist Genomic Region
14056 enhancer of zeste homolog 2 (Drosophila) Details for - - enhancer of zeste homolog 2 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14056 Tuberculist Genomic Region	214917 family with sequence similarity 173, member A Details for - - family with sequence similarity 173, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 214917 Tuberculist Genomic Region
216440 amplified in osteosarcoma Details for - - amplified in osteosarcoma GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216440 Tuberculist Genomic Region	217666 L-2-hydroxyglutarate dehydrogenase Details for - - L-2-hydroxyglutarate dehydrogenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217666 Tuberculist Genomic Region
238024 fructosamine 3 kinase related protein Details for RP23-293H17.3 - fructosamine 3 kinase related protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 238024 Tuberculist Genomic Region	239570 tetratricopeptide repeat domain 38 Details for - - tetratricopeptide repeat domain 38 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 239570 Tuberculist Genomic Region
52592 breast cancer metastasis-suppressor 1-like Details for - - breast cancer metastasis-suppressor 1-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52592 Tuberculist Genomic Region	66200 COMM domain containing 6 Details for - - COMM domain containing 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66200 Tuberculist Genomic Region
66615 autophagy related 4B, cysteine peptidase Details for - - autophagy related 4B, cysteine peptidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66615 Tuberculist Genomic Region	69305 decapping enzyme, scavenger Details for - - decapping enzyme, scavenger GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69305 Tuberculist Genomic Region
71435 Rho GTPase activating protein 21 Details for RP23-436G18.3 - Rho GTPase activating protein 21 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71435 Tuberculist Genomic Region	13433 DNA methyltransferase (cytosine-5) 1 Details for - - DNA methyltransferase (cytosine-5) 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13433 Tuberculist Genomic Region
16413 integrin beta 1 binding protein 1 Details for - - integrin beta 1 binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16413 Tuberculist Genomic Region	17218 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) Details for - - minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17218 Tuberculist Genomic Region
217304 CD300 antigen like family member B Details for - - CD300 antigen like family member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217304 Tuberculist Genomic Region	21898 toll-like receptor 4 Details for RP24-209H15.1 - toll-like receptor 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21898 Tuberculist Genomic Region
228983 oxysterol binding protein-like 2 Details for RP23-16P3.1 - oxysterol binding protein-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228983 Tuberculist Genomic Region	269582 claspin Details for RP23-204N19.4 - claspin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269582 Tuberculist Genomic Region
27419 alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) Details for - - alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27419 Tuberculist Genomic Region	57257 vav 3 oncogene Details for DN-315E9.1 - vav 3 oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57257 Tuberculist Genomic Region
63913 family with sequence similarity 129, member A Details for - - family with sequence similarity 129, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 63913 Tuberculist Genomic Region	67219 mediator complex subunit 18 Details for RP23-63D8.2 - mediator complex subunit 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67219 Tuberculist Genomic Region
68618 RIKEN cDNA 1110012L19 gene Details for RP23-403O11.1 - RIKEN cDNA 1110012L19 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68618 Tuberculist Genomic Region	68675 family with sequence similarity 172, member A Details for - - family with sequence similarity 172, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68675 Tuberculist Genomic Region
69623 zinc finger protein 33B Details for - - zinc finger protein 33B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69623 Tuberculist Genomic Region	70650 zinc finger, CCHC domain containing 8 Details for - - zinc finger, CCHC domain containing 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70650 Tuberculist Genomic Region
72572 spermatogenesis associated, serine-rich 2 Details for - - spermatogenesis associated, serine-rich 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72572 Tuberculist Genomic Region	74455 NOL1/NOP2/Sun domain family member 6 Details for RP23-303M15.1 - NOL1/NOP2/Sun domain family member 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74455 Tuberculist Genomic Region
76454 F-box protein 31 Details for MNCb-2609 - F-box protein 31 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76454 Tuberculist Genomic Region	99138 START domain containing 7 Details for RP23-206D14.5 - START domain containing 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99138 Tuberculist Genomic Region
106795 transcription factor 19 Details for - - transcription factor 19 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106795 Tuberculist Genomic Region	70472 ATPase family, AAA domain containing 2 Details for - - ATPase family, AAA domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70472 Tuberculist Genomic Region
71538 f-box protein 9 Details for MNCb-2471 - f-box protein 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71538 Tuberculist Genomic Region	75415 Rho GTPase activating protein 12 Details for - - Rho GTPase activating protein 12 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75415 Tuberculist Genomic Region
68098 ring finger and CHY zinc finger domain containing 1 Details for - - ring finger and CHY zinc finger domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68098 Tuberculist Genomic Region	74114 carnitine O-octanoyltransferase Details for - - carnitine O-octanoyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74114 Tuberculist Genomic Region
12566 cyclin-dependent kinase 2 Details for - - cyclin-dependent kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12566 Tuberculist Genomic Region

Summary

Members

Details for - - HscB iron-sulfur cluster co-chaperone homolog (E. coli)

Details for RP23-123O10.1 - acetyl-Coenzyme A carboxylase alpha

Details for - - enhancer of zeste homolog 2 (Drosophila)

Details for - - family with sequence similarity 173, member A

Details for - - amplified in osteosarcoma

Details for - - L-2-hydroxyglutarate dehydrogenase

Details for RP23-293H17.3 - fructosamine 3 kinase related protein

Details for - - tetratricopeptide repeat domain 38

Details for - - breast cancer metastasis-suppressor 1-like

Details for - - COMM domain containing 6

Details for - - autophagy related 4B, cysteine peptidase

Details for - - decapping enzyme, scavenger

Details for RP23-436G18.3 - Rho GTPase activating protein 21

Details for - - DNA methyltransferase (cytosine-5) 1

Details for - - integrin beta 1 binding protein 1

Details for - - minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)

Details for - - CD300 antigen like family member B

Details for RP24-209H15.1 - toll-like receptor 4

Details for RP23-16P3.1 - oxysterol binding protein-like 2

Details for RP23-204N19.4 - claspin

Details for - - alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)

Details for DN-315E9.1 - vav 3 oncogene

Details for - - family with sequence similarity 129, member A

Details for RP23-63D8.2 - mediator complex subunit 18

Details for RP23-403O11.1 - RIKEN cDNA 1110012L19 gene

Details for - - family with sequence similarity 172, member A

Details for - - zinc finger protein 33B

Details for - - zinc finger, CCHC domain containing 8

Details for - - spermatogenesis associated, serine-rich 2

Details for RP23-303M15.1 - NOL1/NOP2/Sun domain family member 6

Details for MNCb-2609 - F-box protein 31

Details for RP23-206D14.5 - START domain containing 7

Details for - - transcription factor 19

Details for - - ATPase family, AAA domain containing 2

Details for MNCb-2471 - f-box protein 9

Details for - - Rho GTPase activating protein 12

Details for - - ring finger and CHY zinc finger domain containing 1

Details for - - carnitine O-octanoyltransferase

Details for - - cyclin-dependent kinase 2

GO Terms

3p UTR PITA