PITA_92 megaCluster: 8 Residual: 0.27

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_92	8	0.27	15	0	0.858723	0

Members

Displaying 1 - 45 of 45

TFBS DB TF

TFs	percTargets	pValue
V_NRF1_Q6_M00652	0.555556	0.000000268

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000000000000036	AANAAAACAAA	NA	0.000018	GGCCCCGCCCCC	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_Q6_M00196, V$SP4_Q5_M01273, V$SP1_Q6_01_M00931, V$SP1_Q4_01_M00932, V$SP1_Q2_01_M00933, V$SP1_02_M01303, V$GC_01_M00255, V$SP1_03_M02281, V$ZFP281_01_M01597, V$MAZR_01_M00491, V$KLF7_03_M02773, V$UF1H3BETA_Q6_M01068, V$SP4_03_M02810, V$SP2_01_M01783, V$GKLF_02_M01588, V$CKROX_Q2_M01175, V$E2F3_Q6_M02089, V$ZBP89_Q4_M01816, V$ETF_Q6_M00695, V$SP1_01_M00008, V$SP1SP3_Q4_M01219, V$KROX_Q6_M00982, V$EGR1_Q6_M01873, V$SMAD4_04_M02898, V$ZFP281_04_M02831, V$MAZ_Q6_M00649, V$EGR1_06_M02744, V$ZNF219_01_M01122, V$BCL6B_04_M02844, V$CACD_01_M01113, V$CACBINDINGPROTEIN_Q6_M00720, V$MAZ_Q6_01_M02023, V$WT1_Q6_01_M02036, V$SP4_04_M02914, V$ZFP740_03_M02834, V$RNF96_01_M01199, V$ZFP410_04_M02936, Klf7.1, Sp4.1, Smad3.1, Zfp281.2, Egr1.1, Bcl6b.2, Zfp740.1, Sp4.2, Zfp410.1, Zif268.1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, KLF13_C2H2_full_monomeric_18_1, Klf12_C2H2_DBD_monomeric_15_1, SP8_C2H2_DBD_monomeric_12_1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.13	GCGACG	NA	1.22	TCGCGACG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.45	GACTAG	NA	NA	0.58	NNTGACTA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-214	0.447368	0.00000567

109910 zinc finger protein 91 Details for - - zinc finger protein 91 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109910 Tuberculist Genomic Region	114893 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) Details for - - DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 114893 Tuberculist Genomic Region
13852 syntaxin 2 Details for - - syntaxin 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13852 Tuberculist Genomic Region	140742 sestrin 1 Details for - - sestrin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 140742 Tuberculist Genomic Region
16987 lanosterol synthase Details for - - lanosterol synthase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16987 Tuberculist Genomic Region	17828 biogenesis of lysosomal organelles complex-1, subunit 5, muted Details for - - biogenesis of lysosomal organelles complex-1, subunit 5, muted GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17828 Tuberculist Genomic Region
210789 TBC1 domain family, member 4 Details for - - TBC1 domain family, member 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 210789 Tuberculist Genomic Region	22248 unc-119 homolog (C. elegans) Details for RP23-185A18.16-002 - unc-119 homolog (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22248 Tuberculist Genomic Region
22401 zinc finger matrin type 3 Details for - - zinc finger matrin type 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22401 Tuberculist Genomic Region	229285 spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) Details for - - spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229285 Tuberculist Genomic Region
245867 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 Details for RP23-322G1.5 - protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245867 Tuberculist Genomic Region	26412 mitogen-activated protein kinase kinase kinase kinase 2 Details for - - mitogen-activated protein kinase kinase kinase kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26412 Tuberculist Genomic Region
269254 senataxin Details for RP23-426D2.7 - senataxin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269254 Tuberculist Genomic Region	27878 transcriptional adaptor 1 Details for - - transcriptional adaptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27878 Tuberculist Genomic Region
378702 small EDRK-rich factor 2 Details for - - small EDRK-rich factor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 378702 Tuberculist Genomic Region	66193 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 Details for RP23-161N17.10-001 - PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66193 Tuberculist Genomic Region
67727 syntaxin 17 Details for RP23-122N18.3 - syntaxin 17 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67727 Tuberculist Genomic Region	73747 RIKEN cDNA 1110034G24 gene Details for RP23-391A14.5 - RIKEN cDNA 1110034G24 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73747 Tuberculist Genomic Region
13864 nuclear receptor subfamily 2, group F, member 6 Details for - - nuclear receptor subfamily 2, group F, member 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13864 Tuberculist Genomic Region	212114 NHL repeat containing 3 Details for - - NHL repeat containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 212114 Tuberculist Genomic Region
213081 WD repeat domain 19 Details for - - WD repeat domain 19 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 213081 Tuberculist Genomic Region	216156 WD repeat domain 18 Details for - - WD repeat domain 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216156 Tuberculist Genomic Region
229603 OTU domain containing 7B Details for - - OTU domain containing 7B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229603 Tuberculist Genomic Region	245638 TBC1 domain family, member 8B Details for - - TBC1 domain family, member 8B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245638 Tuberculist Genomic Region
26904 SH2 domain protein 1B1 Details for - - SH2 domain protein 1B1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26904 Tuberculist Genomic Region	381802 tRNA splicing endonuclease 2 homolog (S. cerevisiae) Details for - - tRNA splicing endonuclease 2 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381802 Tuberculist Genomic Region
545938 zinc finger proten 607 Details for - - zinc finger proten 607 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 545938 Tuberculist Genomic Region	54601 forkhead box O4 Details for RP23-356J7.2 - forkhead box O4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54601 Tuberculist Genomic Region
56335 methyltransferase like 3 Details for - - methyltransferase like 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56335 Tuberculist Genomic Region	66377 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1 Details for - - NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66377 Tuberculist Genomic Region
67698 family with sequence similarity 174, member A Details for - - family with sequence similarity 174, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67698 Tuberculist Genomic Region	70381 tectonin beta-propeller repeat containing 1 Details for - - tectonin beta-propeller repeat containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70381 Tuberculist Genomic Region
78038 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) Details for - - methylcrotonoyl-Coenzyme A carboxylase 2 (beta) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78038 Tuberculist Genomic Region	16558 kinesin family member 16B Details for RP23-442B16.1 - kinesin family member 16B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16558 Tuberculist Genomic Region
19060 protein phosphatase 5, catalytic subunit Details for - - protein phosphatase 5, catalytic subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19060 Tuberculist Genomic Region	19765 ralA binding protein 1 Details for - - ralA binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19765 Tuberculist Genomic Region
227333 diacylglycerol kinase, delta Details for - - diacylglycerol kinase, delta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 227333 Tuberculist Genomic Region	236790 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B Details for - - DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 236790 Tuberculist Genomic Region
52504 centromere protein O Details for RP23-6C18.1 - centromere protein O GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52504 Tuberculist Genomic Region	56196 tyrosyl-DNA phosphodiesterase 2 Details for RP23-92G13.1 - tyrosyl-DNA phosphodiesterase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56196 Tuberculist Genomic Region
12041 branched chain ketoacid dehydrogenase kinase Details for - - branched chain ketoacid dehydrogenase kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12041 Tuberculist Genomic Region	23938 mitogen-activated protein kinase kinase 5 Details for - - mitogen-activated protein kinase kinase 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23938 Tuberculist Genomic Region
29858 phosphomannomutase 1 Details for - - phosphomannomutase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 29858 Tuberculist Genomic Region	72050 KDEL (Lys-Asp-Glu-Leu) containing 1 Details for - - KDEL (Lys-Asp-Glu-Leu) containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72050 Tuberculist Genomic Region
74610 ATP-binding cassette, sub-family B (MDR/TAP), member 8 Details for - - ATP-binding cassette, sub-family B (MDR/TAP), member 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74610 Tuberculist Genomic Region

Summary

Members

Details for - - zinc finger protein 91

Details for - - DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)

Details for - - syntaxin 2

Details for - - sestrin 1

Details for - - lanosterol synthase

Details for - - biogenesis of lysosomal organelles complex-1, subunit 5, muted

Details for - - TBC1 domain family, member 4

Details for RP23-185A18.16-002 - unc-119 homolog (C. elegans)

Details for - - zinc finger matrin type 3

Details for - - spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)

Details for RP23-322G1.5 - protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2

Details for - - mitogen-activated protein kinase kinase kinase kinase 2

Details for RP23-426D2.7 - senataxin

Details for - - transcriptional adaptor 1

Details for - - small EDRK-rich factor 2

Details for RP23-161N17.10-001 - PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1

Details for RP23-122N18.3 - syntaxin 17

Details for RP23-391A14.5 - RIKEN cDNA 1110034G24 gene

Details for - - nuclear receptor subfamily 2, group F, member 6

Details for - - NHL repeat containing 3

Details for - - WD repeat domain 19

Details for - - WD repeat domain 18

Details for - - OTU domain containing 7B

Details for - - TBC1 domain family, member 8B

Details for - - SH2 domain protein 1B1

Details for - - tRNA splicing endonuclease 2 homolog (S. cerevisiae)

Details for - - zinc finger proten 607

Details for RP23-356J7.2 - forkhead box O4

Details for - - methyltransferase like 3

Details for - - NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1

Details for - - family with sequence similarity 174, member A

Details for - - tectonin beta-propeller repeat containing 1

Details for - - methylcrotonoyl-Coenzyme A carboxylase 2 (beta)

Details for RP23-442B16.1 - kinesin family member 16B

Details for - - protein phosphatase 5, catalytic subunit

Details for - - ralA binding protein 1

Details for - - diacylglycerol kinase, delta

Details for - - DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

Details for RP23-6C18.1 - centromere protein O

Details for RP23-92G13.1 - tyrosyl-DNA phosphodiesterase 2

Details for - - branched chain ketoacid dehydrogenase kinase

Details for - - mitogen-activated protein kinase kinase 5

Details for - - phosphomannomutase 1

Details for - - KDEL (Lys-Asp-Glu-Leu) containing 1

Details for - - ATP-binding cassette, sub-family B (MDR/TAP), member 8

GO Terms

3p UTR PITA