PITA_99 megaCluster: 1 Residual: 0.23

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_99	1	0.23	14	0	0.861715	0

Members

Displaying 1 - 41 of 41

TFBS DB TF

TFs	percTargets	pValue
SP1_MA0079.2, V_SP1_03_M02281, V_SP1_Q2_01_M00933, V_SP1_Q4_01_M00932	1, 1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0001	AAAAARARAAAA	NA	0.00046	CCCCKCCCCCC	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_03_M02281, V$SP1_Q2_01_M00933, V$SP4_Q5_M01273, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$ZFP281_01_M01597, V$SP1_Q6_01_M00931, V$CKROX_Q2_M01175, V$SP1_02_M01303, V$GC_01_M00255, V$MAZR_01_M00491, V$ZBP89_Q4_M01816, V$SP1SP3_Q4_M01219, V$KLF7_03_M02773, V$ZFP281_04_M02831, V$MAZ_Q6_01_M02023, V$GKLF_02_M01588, V$MAZ_Q6_M00649, V$ZNF219_01_M01122, V$UF1H3BETA_Q6_M01068, V$KROX_Q6_M00982, V$ETF_Q6_M00695, V$CACBINDINGPROTEIN_Q6_M00720, V$SMAD4_04_M02898, V$SP1_01_M00008, V$BCL6B_04_M02844, V$ZFP410_04_M02936, V$SP4_03_M02810, V$CACD_01_M01113, V$E2F3_Q6_M02089, V$EGR1_Q6_M01873, V$SP2_01_M01783, V$ZFP740_03_M02834, V$KLF15_Q2_M01714, V$FKLF_Q5_M01837, V$WT1_Q6_01_M02036, V$EKLF_Q5_M01874, V$FPM315_01_M01587, V$MZF1_01_M00083, V$EGR1_06_M02744, V$WT1_Q6_M01118, V$MZF1_02_M00084, Klf7.1, Zfp281.2, Smad3.1, Zfp410.1, Bcl6b.2, Sp4.1, Zfp740.1, Egr1.1, Ascl2.2, Egr1.2, SP1_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, KLF16_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, SP3_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, Zfp740_C2H2_DBD_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.14	CGCGTC	NA	1.38	CNCGNCGC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.64	TCGTCG	NA	NA	0.63	CTCNTCGG	mmu-mir-714, mmu-mir-375-5p	7mer_m8

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-451	0.433333	0.0000161

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-551b	0.151515	0.0000168

105203 cDNA sequence BC016423 Details for - - cDNA sequence BC016423 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 105203 Tuberculist Genomic Region	12457 CCR4 carbon catabolite repression 4-like (S. cerevisiae) Details for - - CCR4 carbon catabolite repression 4-like (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12457 Tuberculist Genomic Region
12608 CCAAT/enhancer binding protein (C/EBP), beta Details for RP24-151H6.1 - CCAAT/enhancer binding protein (C/EBP), beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12608 Tuberculist Genomic Region	14825 chemokine (C-X-C motif) ligand 1 Details for - - chemokine (C-X-C motif) ligand 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14825 Tuberculist Genomic Region
16656 human immunodeficiency virus type I enhancer binding protein 3 Details for RP23-98J9.1 - human immunodeficiency virus type I enhancer binding protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16656 Tuberculist Genomic Region	19073 serglycin Details for - - serglycin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19073 Tuberculist Genomic Region
192656 receptor (TNFRSF)-interacting serine-threonine kinase 2 Details for RP23-378L22.1 - receptor (TNFRSF)-interacting serine-threonine kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 192656 Tuberculist Genomic Region	216850 KDM1 lysine (K)-specific demethylase 6B Details for RP23-5O23.5 - KDM1 lysine (K)-specific demethylase 6B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216850 Tuberculist Genomic Region
24088 toll-like receptor 2 Details for - - toll-like receptor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 24088 Tuberculist Genomic Region	241694 Ral GTPase activating protein, alpha subunit 2 (catalytic) Details for RP23-185F7.2 - Ral GTPase activating protein, alpha subunit 2 (catalytic) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241694 Tuberculist Genomic Region
347722 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 Details for - - ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 347722 Tuberculist Genomic Region	382551 CD300 antigen like family member H Details for RP23-331L12.8 - CD300 antigen like family member H GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 382551 Tuberculist Genomic Region
50772 mitogen-activated protein kinase 6 Details for - - mitogen-activated protein kinase 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 50772 Tuberculist Genomic Region	54720 regulator of calcineurin 1 Details for - - regulator of calcineurin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54720 Tuberculist Genomic Region
58250 carbohydrate sulfotransferase 11 Details for - - carbohydrate sulfotransferase 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 58250 Tuberculist Genomic Region	635504 predicted gene 7160 Details for - - predicted gene 7160 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 635504 Tuberculist Genomic Region
66895 PX domain containing 1 Details for - - PX domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66895 Tuberculist Genomic Region	68567 cell growth regulator with EF hand domain 1 Details for - - cell growth regulator with EF hand domain 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68567 Tuberculist Genomic Region
70686 dual specificity phosphatase 16 Details for - - dual specificity phosphatase 16 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70686 Tuberculist Genomic Region	74120 zinc finger protein 263 Details for - - zinc finger protein 263 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74120 Tuberculist Genomic Region
105522 ankyrin repeat domain 28 Details for - - ankyrin repeat domain 28 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 105522 Tuberculist Genomic Region	112407 EGL nine homolog 3 (C. elegans) Details for - - EGL nine homolog 3 (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 112407 Tuberculist Genomic Region
12977 colony stimulating factor 1 (macrophage) Details for - - colony stimulating factor 1 (macrophage) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12977 Tuberculist Genomic Region	14173 fibroblast growth factor 2 Details for DN-452A22.6 - fibroblast growth factor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14173 Tuberculist Genomic Region
16177 interleukin 1 receptor, type I Details for - - interleukin 1 receptor, type I GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16177 Tuberculist Genomic Region	18413 oncostatin M Details for RP23-453B22.1 - oncostatin M GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18413 Tuberculist Genomic Region
20448 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 Details for RP23-17P12.1 - ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20448 Tuberculist Genomic Region	213053 solute carrier family 39 (zinc transporter), member 14 Details for - - solute carrier family 39 (zinc transporter), member 14 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 213053 Tuberculist Genomic Region
240672 dual specificity phosphatase 5 Details for - - dual specificity phosphatase 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240672 Tuberculist Genomic Region	327900 ubiquitin domain containing 2 Details for RP23-395O6.1 - ubiquitin domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 327900 Tuberculist Genomic Region
330122 chemokine (C-X-C motif) ligand 3 Details for - - chemokine (C-X-C motif) ligand 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 330122 Tuberculist Genomic Region	433926 leucine rich repeat containing 8 family, member B Details for - - leucine rich repeat containing 8 family, member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 433926 Tuberculist Genomic Region
71973 RNA binding protein with multiple splicing 2 Details for - - RNA binding protein with multiple splicing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71973 Tuberculist Genomic Region	72504 TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor Details for - - TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72504 Tuberculist Genomic Region
76650 sulfiredoxin 1 homolog (S. cerevisiae) Details for - - sulfiredoxin 1 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76650 Tuberculist Genomic Region	77633 G1 to S phase transition pseudogene Details for - - G1 to S phase transition pseudogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77633 Tuberculist Genomic Region
81703 Jun dimerization protein 2 Details for - - Jun dimerization protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 81703 Tuberculist Genomic Region	104252 CDC42 effector protein (Rho GTPase binding) 2 Details for - - CDC42 effector protein (Rho GTPase binding) 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104252 Tuberculist Genomic Region
18550 furin (paired basic amino acid cleaving enzyme) Details for - - furin (paired basic amino acid cleaving enzyme) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18550 Tuberculist Genomic Region	19730 ral guanine nucleotide dissociation stimulator Details for RP23-430H1.6 - ral guanine nucleotide dissociation stimulator GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19730 Tuberculist Genomic Region
71409 formin-like 2 Details for RP23-282A22.1 - formin-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71409 Tuberculist Genomic Region

Summary

Members

Details for - - cDNA sequence BC016423

Details for - - CCR4 carbon catabolite repression 4-like (S. cerevisiae)

Details for RP24-151H6.1 - CCAAT/enhancer binding protein (C/EBP), beta

Details for - - chemokine (C-X-C motif) ligand 1

Details for RP23-98J9.1 - human immunodeficiency virus type I enhancer binding protein 3

Details for - - serglycin

Details for RP23-378L22.1 - receptor (TNFRSF)-interacting serine-threonine kinase 2

Details for RP23-5O23.5 - KDM1 lysine (K)-specific demethylase 6B

Details for - - toll-like receptor 2

Details for RP23-185F7.2 - Ral GTPase activating protein, alpha subunit 2 (catalytic)

Details for - - ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

Details for RP23-331L12.8 - CD300 antigen like family member H

Details for - - mitogen-activated protein kinase 6

Details for - - regulator of calcineurin 1

Details for - - carbohydrate sulfotransferase 11

Details for - - predicted gene 7160

Details for - - PX domain containing 1

Details for - - cell growth regulator with EF hand domain 1

Details for - - dual specificity phosphatase 16

Details for - - zinc finger protein 263

Details for - - ankyrin repeat domain 28

Details for - - EGL nine homolog 3 (C. elegans)

Details for - - colony stimulating factor 1 (macrophage)

Details for DN-452A22.6 - fibroblast growth factor 2

Details for - - interleukin 1 receptor, type I

Details for RP23-453B22.1 - oncostatin M

Details for RP23-17P12.1 - ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

Details for - - solute carrier family 39 (zinc transporter), member 14

Details for - - dual specificity phosphatase 5

Details for RP23-395O6.1 - ubiquitin domain containing 2

Details for - - chemokine (C-X-C motif) ligand 3

Details for - - leucine rich repeat containing 8 family, member B

Details for - - RNA binding protein with multiple splicing 2

Details for - - TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor

Details for - - sulfiredoxin 1 homolog (S. cerevisiae)

Details for - - G1 to S phase transition pseudogene

Details for - - Jun dimerization protein 2

Details for - - CDC42 effector protein (Rho GTPase binding) 2

Details for - - furin (paired basic amino acid cleaving enzyme)

Details for RP23-430H1.6 - ral guanine nucleotide dissociation stimulator

Details for RP23-282A22.1 - formin-like 2

GO Terms

3p UTR PITA