TargetScan_107 megaCluster: 1 Residual: 0.13

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_107 1 0.13 15 0 0.968093 0

Members

Displaying 1 - 25 of 25
107569 5'-nucleotidase, cytosolic III

Details for - - 5'-nucleotidase, cytosolic III

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 107569

Tuberculist Genomic Region

14528 GTP cyclohydrolase 1

Details for - - GTP cyclohydrolase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14528

Tuberculist Genomic Region

17873 growth arrest and DNA-damage-inducible 45 beta

Details for - - growth arrest and DNA-damage-inducible 45 beta

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17873

Tuberculist Genomic Region

21939 CD40 antigen

Details for RP23-428M13.1 - CD40 antigen

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 21939

Tuberculist Genomic Region

229227 RIKEN cDNA 4932438A13 gene

Details for CT7-315N12.1 - RIKEN cDNA 4932438A13 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 229227

Tuberculist Genomic Region

320129 adrenergic receptor kinase, beta 2

Details for - - adrenergic receptor kinase, beta 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 320129

Tuberculist Genomic Region

320509 RIKEN cDNA 9930022D16 gene

Details for RP23-465A12.2 - RIKEN cDNA 9930022D16 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 320509

Tuberculist Genomic Region

434484 Sp140 nuclear body protein

Details for - - Sp140 nuclear body protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 434484

Tuberculist Genomic Region

547253 poly (ADP-ribose) polymerase family, member 14

Details for - - poly (ADP-ribose) polymerase family, member 14

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 547253

Tuberculist Genomic Region

71982 sorting nexin 10

Details for - - sorting nexin 10

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71982

Tuberculist Genomic Region

14042 exostoses (multiple) 1

Details for - - exostoses (multiple) 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14042

Tuberculist Genomic Region

16193 interleukin 6

Details for - - interleukin 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16193

Tuberculist Genomic Region

20821 tripartite motif-containing 21

Details for - - tripartite motif-containing 21

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20821

Tuberculist Genomic Region

214855 AT rich interactive domain 5A (MRF1-like)

Details for - - AT rich interactive domain 5A (MRF1-like)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 214855

Tuberculist Genomic Region

218613 mesoderm induction early response 1, family member 3

Details for - - mesoderm induction early response 1, family member 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 218613

Tuberculist Genomic Region

22670 tripartite motif-containing 26

Details for RP23-77N9.1 - tripartite motif-containing 26

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22670

Tuberculist Genomic Region

238393 serine (or cysteine) peptidase inhibitor, clade A, member 3F

Details for - - serine (or cysteine) peptidase inhibitor, clade A, member 3F

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 238393

Tuberculist Genomic Region

240354 mucosa associated lymphoid tissue lymphoma translocation gene 1

Details for - - mucosa associated lymphoid tissue lymphoma translocation gene 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 240354

Tuberculist Genomic Region

245944 vacuolar protein sorting 54 (yeast)

Details for RP23-154K13.1 - vacuolar protein sorting 54 (yeast)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 245944

Tuberculist Genomic Region

257632 nucleotide-binding oligomerization domain containing 2

Details for - - nucleotide-binding oligomerization domain containing 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 257632

Tuberculist Genomic Region

268301 sosondowah ankyrin repeat domain family member C

Details for - - sosondowah ankyrin repeat domain family member C

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 268301

Tuberculist Genomic Region

319448 fibronectin type III domain containing 3A

Details for - - fibronectin type III domain containing 3A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 319448

Tuberculist Genomic Region

84035 kringle containing transmembrane protein 1

Details for RP23-293J16.1 - kringle containing transmembrane protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 84035

Tuberculist Genomic Region

628705 PHD finger protein 11C

Details for mCG_1037415 - PHD finger protein 11C

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 628705

Tuberculist Genomic Region

67245 pellino 1

Details for RP23-93O11.1 - pellino 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67245

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
V_ICSBP_Q6_M00699 0.416667 0.000000447

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.011 MRAGAAAAMAMA FOXA1_MA0148.1, FOXF2_MA0030.1, Foxa2_MA0047.2, Foxd3_MA0041.1, FOXD1_MA0031.1, Evi1_MA0029.1, FOXO3_MA0157.1, V$FOXA2_04_M02749, V$HNF3A_01_M01261, V$FOXO1_Q5_M01216, V$FREAC3_01_M00291, V$FOXJ1_03_M02750, V$FREAC4_01_M00292, V$HNF3B_Q6_M02014, V$FOXK1_03_M02752, V$HNF3_Q6_01_M01012, V$FREAC2_01_M00290, V$FOXL1_04_M02753, V$HNF3ALPHA_Q6_M00724, V$FOXO1_02_M00474, Foxa2.1, Foxj3.2, Foxj1.1, Foxk1.1, Foxl1.1 1.2 TGGGYGGGGNGR Klf4_MA0039.2, SP1_MA0079.2, V$GKLF_02_M01588, V$KLF7_03_M02773, V$SP1_02_M01303, V$SP1_Q6_01_M00931, V$SP4_Q5_M01273, V$SP1_Q4_01_M00932, V$CACD_01_M01113, V$MAZR_01_M00491, V$SP1_Q6_M00196, V$SP1_Q2_01_M00933, V$ZFP740_03_M02834, V$EKLF_Q5_M01874, V$ZFP281_01_M01597, V$ZFP281_04_M02831, V$GC_01_M00255, V$MAZ_Q6_01_M02023, V$CKROX_Q2_M01175, V$UF1H3BETA_Q6_M01068, V$ZNF219_01_M01122, V$CACCCBINDINGFACTOR_Q6_M00721, V$SP1_03_M02281, V$ZBP89_Q4_M01816, V$MAZ_Q6_M00649, V$SMAD4_04_M02898, V$GLI3_Q5_01_M01657, V$ASCL2_04_M02841, V$NFE4_Q5_M02105, V$FKLF_Q5_M01837, V$SP1_01_M00008, V$SOX14_04_M02901, V$SP3_Q3_M00665, V$E2F3_Q6_M02089, V$GLI3_01_M01596, V$EGR2_Q6_M02092, V$BCL6B_04_M02844, Klf7.1, Zfp740.1, Zfp281.2, Smad3.1, Ascl2.2, Sox13.2, Bcl6b.2, Zfp410.1, Egr1.2, Egr1.1, Zif268.1, Sp4.1, Zbtb7b.1, ZNF740_C2H2_full_monomeric_10_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, SP4_C2H2_full_monomeric_17_1, Klf12_C2H2_DBD_monomeric_15_1

Upstream Weeder Motif

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.63 TCGCGC NA NA 0.72 CRGCTCGA NA NA

3p UTR PITA

miRNAs percTargets pValue
mmu-miR-542-3p 0.833333 0.00000649

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-3101 0.454545 0.000000411

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