TargetScan_127 megaCluster: 10 Residual: 0.19

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_127 10 0.19 15 0 0.932903 0

Members

Displaying 1 - 38 of 38
110460 acetyl-Coenzyme A acetyltransferase 2

Details for - - acetyl-Coenzyme A acetyltransferase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 110460

Tuberculist Genomic Region

22129 tetratricopeptide repeat domain 3

Details for - - tetratricopeptide repeat domain 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22129

Tuberculist Genomic Region

245688 retinoblastoma binding protein 7

Details for RP23-436I3.1 - retinoblastoma binding protein 7

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 245688

Tuberculist Genomic Region

51944 kinetochore-localized astrin/SPAG5 binding

Details for RP23-172B16.7 - kinetochore-localized astrin/SPAG5 binding

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 51944

Tuberculist Genomic Region

56248 adenylate kinase 3

Details for - - adenylate kinase 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56248

Tuberculist Genomic Region

66071 ethylmalonic encephalopathy 1

Details for - - ethylmalonic encephalopathy 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66071

Tuberculist Genomic Region

74196 tetratricopeptide repeat domain 27

Details for - - tetratricopeptide repeat domain 27

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74196

Tuberculist Genomic Region

100088 regulator of chromosome condensation 1

Details for WI1-2643G14.3 - regulator of chromosome condensation 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100088

Tuberculist Genomic Region

109658 taxilin alpha

Details for RP23-151A15.8 - taxilin alpha

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 109658

Tuberculist Genomic Region

110074 deoxyuridine triphosphatase

Details for RP23-216B20.3 - deoxyuridine triphosphatase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 110074

Tuberculist Genomic Region

15254 histidine triad nucleotide binding protein 1

Details for RP24-84L18.1 - histidine triad nucleotide binding protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15254

Tuberculist Genomic Region

20133 ribonucleotide reductase M1

Details for - - ribonucleotide reductase M1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20133

Tuberculist Genomic Region

20419 Shc SH2-domain binding protein 1

Details for - - Shc SH2-domain binding protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20419

Tuberculist Genomic Region

21843 Tia1 cytotoxic granule-associated RNA binding protein-like 1

Details for - - Tia1 cytotoxic granule-associated RNA binding protein-like 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 21843

Tuberculist Genomic Region

21973 topoisomerase (DNA) II alpha

Details for RP23-333D2.5 - topoisomerase (DNA) II alpha

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 21973

Tuberculist Genomic Region

22171 thymidylate synthase

Details for - - thymidylate synthase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22171

Tuberculist Genomic Region

225659 centrosomal protein 76

Details for - - centrosomal protein 76

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 225659

Tuberculist Genomic Region

228033 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

Details for RP23-146O7.1 - ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 228033

Tuberculist Genomic Region

234258 nei like 3 (E. coli)

Details for - - nei like 3 (E. coli)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 234258

Tuberculist Genomic Region

244962 sorting nexin 14

Details for AC116713.1 - sorting nexin 14

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 244962

Tuberculist Genomic Region

329506 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2

Details for RP23-34E24.1 - CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 329506

Tuberculist Genomic Region

445007 nucleoporin 85

Details for RP23-392H19.11-001 - nucleoporin 85

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 445007

Tuberculist Genomic Region

52163 calcium/calmodulin-dependent protein kinase I

Details for - - calcium/calmodulin-dependent protein kinase I

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 52163

Tuberculist Genomic Region

67037 polyamine-modulated factor 1

Details for - - polyamine-modulated factor 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67037

Tuberculist Genomic Region

67163 coiled-coil domain containing 47

Details for RP23-81G14.10-001 - coiled-coil domain containing 47

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67163

Tuberculist Genomic Region

67241 structural maintenance of chromosomes 6

Details for - - structural maintenance of chromosomes 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67241

Tuberculist Genomic Region

67472 mitochondrial fission regulator 1

Details for - - mitochondrial fission regulator 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67472

Tuberculist Genomic Region

67738 peptidylprolyl isomerase D (cyclophilin D)

Details for - - peptidylprolyl isomerase D (cyclophilin D)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67738

Tuberculist Genomic Region

68646 NAD kinase 2, mitochondrial

Details for - - NAD kinase 2, mitochondrial

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68646

Tuberculist Genomic Region

75570 nonhomologous end-joining factor 1

Details for - - nonhomologous end-joining factor 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 75570

Tuberculist Genomic Region

16880 leukemia inhibitory factor receptor

Details for - - leukemia inhibitory factor receptor

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16880

Tuberculist Genomic Region

20359 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B

Details for - - sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20359

Tuberculist Genomic Region

211651 Fanconi anemia, complementation group D2

Details for - - Fanconi anemia, complementation group D2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 211651

Tuberculist Genomic Region

381318 NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)

Details for - - NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 381318

Tuberculist Genomic Region

80905 polymerase (DNA directed), eta (RAD 30 related)

Details for - - polymerase (DNA directed), eta (RAD 30 related)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 80905

Tuberculist Genomic Region

67041 3-oxoacid CoA transferase 1

Details for - - 3-oxoacid CoA transferase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67041

Tuberculist Genomic Region

98711 retinol dehydrogenase 10 (all-trans)

Details for - - retinol dehydrogenase 10 (all-trans)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 98711

Tuberculist Genomic Region

14211 structural maintenance of chromosomes 2

Details for RP23-122I3.3 - structural maintenance of chromosomes 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14211

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
V_E2_Q6_01_M00928 0.210526 0.0000167

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.00013 AAAAAAAMAAAA NA 400 CTGCGCANGCGC V$ZFP206_01_M01742, V$NRF1_Q6_M00652, NRF1_NRF_full_dimeric_12_1

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.43 ATCGCG NA 1.37 NTCGCGGC NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.4 TCGTAC NA NA 0.55 TTCNTCCN NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
NA

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